DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tbc1d15-17 and CG8155

DIOPT Version :9

Sequence 1:	NP_001259806.1	Gene:	Tbc1d15-17 / 33184	FlyBaseID:	FBgn0031233	Length:	715	Species:	Drosophila melanogaster
Sequence 2:	NP_611029.3	Gene:	CG8155 / 36698	FlyBaseID:	FBgn0034009	Length:	1098	Species:	Drosophila melanogaster

Alignment Length:	284	Identity:	91/284 - (32%)
Similarity:	141/284 - (49%)	Gaps:	40/284 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   318 ETLNAQDEKIVNNLPDRQRVERGHPLTETQWLEFQTPDGRISDSARIKELIFRGGVVQSLRPEVW 382
            :..|..:|.:. |||.|.      |:.::::..|....|:|.....:..:||.||:..|||..||
  Fly   179 KAFNLSEEHMA-NLPPRP------PMCDSEFRLFLDALGQIQRKDELHRVIFLGGIDPSLRRVVW 236

  Fly   383 KFLLNYY------LWSDTHVERIERRKQKSIEYYNMKAQW------------LAMTTTQEANFCG 429
            |.|||.|      |..|.| :|:|..::||.:|..::..|            ||..|:
  Fly   237 KHLLNVYPGGANGLALDGH-QRMEFMRRKSEQYCRLRDTWKAAVKRGSVAGELAYVTS------- 293

  Fly   430 YRERKCQIEKDVKRTDRSLQFFAG-EDNPNLTLLQGILMTYVMYNFDLGYVQGMSDLLAPILEIQ 493
                  .::|||.||||...|:|| :||.|:..|..||.||.:.:..:.|.|||||:.:|:|...
  Fly   294 ------MVKKDVLRTDRLHPFYAGSDDNQNIAALFNILTTYALNHPSVSYCQGMSDIASPLLVTM 352

  Fly   494 VNEVDTFWCFVGFMELVFTNFDIDQAGMKTQFAQIRRLIEFANAPLFNYMRSHDSDNMYFCFRWL 558
            .:|...:.||...|..:..||.:|...|..:||.:...:.|.:...:.|::|..:|::.||:|||
  Fly   353 NDEAQAYICFCAIMSRMRGNFMLDGIAMTQKFAHLTEALSFYDPEFWEYLKSQQADDLLFCYRWL 417

  Fly   559 LVWYKRELNSEDVLKLWECLWTRL 582
            |:..|||...||.|::.|..|:.|
  Fly   418 LLELKREFPFEDALRMLEVQWSSL 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_001259806.1	DUF3548	37..>191	CDD:192931
Tbc1d15-17	NP_001259806.1	TBC	369..598	CDD:214540	80/233 (34%)
CG8155	NP_611029.3	TBC	225..439	CDD:214540	77/227 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456566
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1495285at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR22957
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850