Protein Alignment Tbc1d15-17 and Tbc1d14

DIOPT Version :9

• Sequence 1: NP_001259806.1
• Gene: Tbc1d15-17 / 33184
• FlyBaseID: FBgn0031233
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_001106836.1
• Gene: Tbc1d14 / 360956
• RGDID: 1309993
• Length: 714
• Species: Rattus norvegicus
• Alignment Length: 682
• Identity: 138/682 - (20%)
• Similarity: 234/682 - (34%)
• Gaps: 217/682 - (31%)

  Fly    47 GVLLKKASAEHIADLNTSGSL---------------SLVEYSR-SIAEMPRRRLLLEWQPNDSIM 95
            |:::|.:|...:.|.|.|.|:               ||.|... ||..:||...:.::.|...:.
  Rat    10 GLMVKVSSWTKMTDGNLSTSMNGVALMGILDGRPGDSLQELQHLSIKAVPRSLSVPDYGPTLKLG 74

  Fly    96 IADD-----SQDQGDWAL--------------VDRISGRTRTTSECRAFNT-------RPIEPSG 134
            ..:|     |.|.|...|              |.|....:....| |||.:       .|..|:|
  Rat    75 ALEDRHSLQSVDSGIPTLEIGNPEPVPCSVVHVKRKQSESEIIPE-RAFQSACPLPSCTPSAPTG 138

  Fly   135 GATTRSRVMRAQLEDLSSVEVRHRGQTIR----FMRKGANGVHSEFFFQHGNA-----DLFV--- 187
            .                     .|.|.:|    |.|.|.:.|  :.:.....|     |:.|
  Rat   139 S---------------------EREQAVRKSSTFPRTGYDSV--KLYSPTSKALSRSDDVSVCSV 180

  Fly   188 ----------RSMRDQHLIENAETSRSGGEVYAILTTENQKLKKTFAELDIGQIK-ASQLPRESW 241
                      .|:.::.:::...||.|.    ||:|.||.. ...|.::.:..|| .|.|.::..
  Rat   181 SSLGTELSTTLSVSNEDILDLMVTSNSS----AIVTLENDD-DPQFTDVTLSSIKETSDLHQQDC 240

  Fly   242 LPNKLAG-----------------------------------ILGNIP--DYVQPPFQRSPK--- 266
            :.....|                                   :.|.:|  :..|...:::.|
  Rat   241 VAETEEGRKLRLLQPFSHFFTRNLLARKQNARLDRQRDLGWKLFGKVPLRETAQKDSKKTQKEYE 305

  Fly   267 ---SRPGVLISGDRQTSPDNYQIIGLSGSTNSACSSNGQSRGGSAEKSPADSELETLNAQDEKIV 328
               .||      .|..||.......|.....|..:...:.|..:....||:...:.....:|.:|
  Rat   306 DKAGRP------SRPPSPKQNVRKNLDFEPLSTTALILEDRPANLPAKPAEEAQKHRQQYEEMVV 364

  Fly   329 --------------NNLPDRQRVER--GH----------PLTETQWLEFQTPDGRISDSARIKEL 367
                          ..|.:|.:||.  |:          |..||.|.           |.::::|
  Rat   365 QAKKRELKEAQRRKKQLEERCKVEESIGNAVLTWNNEILPNWETMWC-----------SKKVRDL 418

  Fly   368 IFRGGVVQSLRPEVWKFLLNYYLWSDTHVERIERRKQKSIEYYNM-----KAQWLAMTT------ 421
            .:: |:..|:|.:||...:...| :.||            |.:::     |.:|.:::|
  Rat   419 WWQ-GIPPSVRGKVWSLAIGNEL-NITH------------ELFDICLARAKERWRSLSTGGSEVE 469

  Fly   422 TQEANF-CGYRERKCQIEK-DVKRTDRSLQFFAGEDNPNLTLLQGILMTYVMYNFDLGYVQGMSD 484
            .::|.| ...||...::.| |:.||..:|..|. :..|...:|..||..|..|..|:|||||||
  Rat   470 NEDAGFSAADREASLELIKLDISRTFPNLCIFQ-QGGPYHDMLHSILGAYTCYRPDVGYVQGMS- 532

  Fly   485 LLAPILEIQVNEVDTFWCFVGFM----ELVFTNFDIDQAGMKTQFAQIRRLIEFANAP-LFNYMR 544
            .:|.:|.:.::..|.|..|...:    ::.|  |.:|...|.|.||......| .|.| ||.:.:
  Rat   533 FIAAVLILNLDTADAFIAFSNLLNKPCQMAF--FRVDHGLMLTYFAAFEVFFE-ENLPKLFAHFK 594

  Fly   545 SHDSDNMYFCFRWLLVWYKRELNSEDVLKLWE 576
            .::.....:...|:...|.:.|..:...::|:
  Rat   595 KNNLTADIYLIDWIFTLYSKSLPLDLACRIWD 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_001259806.1	DUF3548	37..>191	CDD:192931	40/207 (19%)
		TBC	369..598	CDD:214540	57/226 (25%)
Tbc1d14	NP_001106836.1	DUF4207	147..384	CDD:290615	39/249 (16%)
		TBC	419..651	CDD:214540	57/227 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.810