Protein Alignment Tbc1d15-17 and Tbc1d25

DIOPT Version :9

• Sequence 1: NP_001259806.1
• Gene: Tbc1d15-17 / 33184
• FlyBaseID: FBgn0031233
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_001100425.1
• Gene: Tbc1d25 / 302552
• RGDID: 1559711
• Length: 688
• Species: Rattus norvegicus
• Alignment Length: 499
• Identity: 139/499 - (27%)
• Similarity: 218/499 - (43%)
• Gaps: 99/499 - (19%)

  Fly   118 TTSECR--AFNTRPIEPSGGATTRSRVMRAQLEDLSSVEVRHRGQTIRFMRKGANGVHSEF---- 176
            |||...  |.:..| .|.|||:..:.|   :.|:...|.||        ::|..:.:..||
  Rat     3 TTSAASDLACSAAP-SPVGGASAAAAV---EEEEREVVRVR--------VKKCESFLSPEFRSFA 55

  Fly   177 ---------FFQHGNADLFVRSMRDQHLIENAETSRSGGEVYAILTTENQKLKKTFA-------- 224
                     ..||.....|..:.:....|......|.|.|.:..|.:: ..|...||
  Rat    56 VDPQITSLDVLQHILIRAFDLNGKKNFGISYLARDRLGQEAFLSLLSD-WDLSTAFATASKPYLQ 119

  Fly   225 -ELDIGQIKASQLPRESWLPNKLAGILGNIPDYVQPPFQRSPKSRPG--VLISGDRQTS------ 280
             .:||...:.|.| .|.|             |.:      |||...|  ||:: |:::|
  Rat   120 LRVDIRPSEDSPL-LEDW-------------DII------SPKDVIGSDVLLA-DKRSSLTTAAL 163

  Fly   281 PDNYQIIGLSGSTNSACSSNGQSRGGSAEKSPADSELETLNAQDEKIVNNLPDRQRVERGHPLTE 345
            |....|:...|.|                .|.....|.....:|.|     |.:.      ||::
  Rat   164 PFTQSILSQVGRT----------------LSKVQQVLSWSYGEDVK-----PFKP------PLSD 201

  Fly   346 TQWLEFQTPDGRISDSARIKELIFRGGVVQSLRPEVWKFLLNYYLWSDTHVERIERRKQKSIEYY 410
            .::..:...:|::|....::..|:.|||..|||..||::|||.|....|..||::..|:||.||.
  Rat   202 AEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKSREYE 266

  Fly   411 NMKAQWLAMTTTQEANFCGYRERKCQIEKDVKRTDRSLQFFAG-EDNPNLTLLQGILMTYVMYNF 474
            .:|::|......::..|.     :..:.|||.||||:..::|| ||.|:|..|..:|.||.:.:.
  Rat   267 QLKSEWAQRVNPEDLEFI-----RSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYAVTHP 326

  Fly   475 DLGYVQGMSDLLAPILEIQVNEVDTFWCFVGFMELVFTNFDIDQAGMKTQFAQIRRLIEFANAPL 539
            .:.|.||||||.:|||.:..:|...|.||.|.|:.:..||..|...|.|:||.::.|:..|:...
  Rat   327 QVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHADPDF 391

  Fly   540 FNYMRSHDSDNMYFCFRWLLVWYKRELNSEDVLKLWECLWTRLP 583
            :.|::...:|:::||:||||:..|||...:|.|::.|..|:.||
  Rat   392 YQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLP 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_001259806.1	DUF3548	37..>191	CDD:192931	20/87 (23%)
		TBC	369..598	CDD:214540	82/216 (38%)
Tbc1d25	NP_001100425.1	TBC	225..454	CDD:214540	82/216 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1495285at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.820