Protein Alignment Tbc1d15-17 and Tbc1d17

DIOPT Version :9

• Sequence 1: NP_001259806.1
• Gene: Tbc1d15-17 / 33184
• FlyBaseID: FBgn0031233
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_001099728.1
• Gene: Tbc1d17 / 292886
• RGDID: 1309686
• Length: 646
• Species: Rattus norvegicus
• Alignment Length: 663
• Identity: 217/663 - (32%)
• Similarity: 308/663 - (46%)
• Gaps: 107/663 - (16%)

  Fly    41 ILFTHDGVLLKKASAEH-IADLNTSGSLSLVEYSRSIAEMPRRRLLLEWQP----NDSIMIADDS 100
            ::|...||.|..::.:| ..|...:|.|.:||....:        ||.|.|    .|...|....
  Rat     8 VVFEKGGVYLHTSARKHQDPDSLIAGVLRVVEKDNDV--------LLHWAPVEEAGDPTQIFFSK 64

  Fly   101 QD-------------------QGDWALVDRISGRTRTTSECRAFNTRPIEPSGGATTRSRVMRAQ 146
            :|                   :.|||::..:..|.. .:|.|    |..|||  :...|......
  Rat    65 KDPSGGEPSTSEEEPTFDPGYEPDWAVISTVRPRPH-LAEPR----RGAEPS--SPRSSWAFSVS 122

  Fly   147 LEDLSSVEVRHRGQTIRF--MRKGANGVHSEFFFQHGNADLFVRSMRDQHLIENAETSRSGGEVY 209
            |.:|.|:.....|.:..:  :...|.|......|..|.....:|.:....|:   .:|.....:|
  Rat   123 LGELKSIRRSKPGLSWAYLVLVTQAGGSLPALHFHRGGTRALLRVLSRYLLL---ASSPQDSRLY 184

  Fly   210 AILTTENQKLKKTFAELDIGQIKASQLPRESWLPNKLAGILGNIPDYVQPPFQR--SPKSRPGVL 272
            .:...:...|..:|..|.:....:|.:                :..::|.|:..  |..||....
  Rat   185 LVFPQDPSALSDSFHHLQLFDQDSSNV----------------VSRFLQDPYSTTFSSFSRVTNF 233

  Fly   273 ISGDRQTSPDNYQIIGLSGSTNSACSSNGQSRGGSAEKSP--ADSE----LETLNAQDEKIVNNL 331
            ..|..|..|:                      |.|:...|  .|.|    .|.::..:      |
  Rat   234 FRGALQPHPE----------------------GASSPDLPPLPDDEPEPGFEVISCVE------L 270

  Fly   332 PDRQRVERGHPLTETQWLEFQTPDGRISDSARIKELIFRGGVVQSLRPEVWKFLLNYYLWSDTHV 396
            ..|..|||..|:||.:|.....|:||:.:...:|..||.||:...||.|.|||||.|..|..:..
  Rat   271 GQRPTVERAPPVTEEEWNRHVGPEGRLQNVPELKSRIFSGGLSPGLRREAWKFLLGYLSWESSAE 335

  Fly   397 ERIERRKQKSIEYYNMKAQWLAMTTTQEAN---FCGYRERKCQIEKDVKRTDRSLQFFAGEDNPN 458
            |.....::|:.||:.||.||.:::..||..   ..|||.   .||:||.||||:.:|:.|.:||.
  Rat   336 EHKAHVRKKTDEYFRMKLQWKSVSAEQERRNSLLHGYRS---LIERDVSRTDRTNKFYEGPENPG 397

  Fly   459 LTLLQGILMTYVMYNFDLGYVQGMSDLLAPILEIQVNEVDTFWCFVGFMELVFTNFDIDQAGMKT 523
            |.||..||:||.||:|||||||||||||:|||.:..||||.||||.||||||..||:..|..||.
  Rat   398 LGLLNDILLTYCMYHFDLGYVQGMSDLLSPILFVVQNEVDAFWCFCGFMELVHGNFEESQETMKR 462

  Fly   524 QFAQIRRLIEFANAPLFNYMRSHDSDNMYFCFRWLLVWYKRELNSEDVLKLWECLWTRLPCPNFH 588
            |..|:..|:...:.||.:::.|.||.::.|||||||:|:|||....|||:|||.|||.||.||.|
  Rat   463 QLGQLLLLLRVLDQPLCDFLDSQDSGSLCFCFRWLLIWFKREFPFPDVLRLWEVLWTGLPGPNLH 527

  Fly   589 LLFSVAILDQETRVIIDSQYEFTEILKHVNELSGNIDVQKTLQVAEGIYLQLKGSETLPNDIRSI 653
            ||.:.||||.|...::.|.:...|||||:|||:..:.|:..|..||.:|.||.....||::::.|
  Rat   528 LLVACAILDMERDTLMLSGFGSNEILKHINELTMKLSVEDVLTRAEALYRQLTACPELPHNVQEI 592

  Fly   654 IG-----EPLLPA 661
            :|     ||..|:
  Rat   593 LGLAQPEEPSSPS 605

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_001259806.1	DUF3548	37..>191	CDD:192931	37/175 (21%)
		TBC	369..598	CDD:214540	120/231 (52%)
Tbc1d17	NP_001099728.1	DUF3548	3..218	CDD:192931	44/243 (18%)
		TBC	308..543	CDD:214540	122/237 (51%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	252	1.000	Domainoid score	I2022
eggNOG	1	0.900	-	-		E1_COG5210
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1495285at2759
OrthoFinder	1	1.000	-	-		FOG0002107
OrthoInspector	1	1.000	-	-		otm45654
orthoMCL	1	0.900	-	-		OOG6_101355
Panther	1	1.100	-	-	LDO	PTHR22957
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1395
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.780