Protein Alignment Tbc1d15-17 and Sgsm1

DIOPT Version :10

• Sequence 1: NP_608503.1
• Gene: Tbc1d15-17 / 33184
• FlyBaseID: FBgn0031233
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: XP_063127295.1
• Gene: Sgsm1 / 288743
• RGDID: 1308178
• Length: 1148
• Species: Rattus norvegicus
• Alignment Length: 1019
• Identity: 191/1019 - (18%)
• Similarity: 307/1019 - (30%)
• Gaps: 463/1019 - (45%)

  Fly     2 DESVRYDRCHQVQL-------------------GVFNESQLSSVEEDVQNLPQQGTGNILFTHDG 47
            ||.|:..|.|...|                   |..::....|..:.|::|.|.....:|:..:.
  Rat   198 DELVQRHRIHSSHLRQDSPTKRPALCIQKRHSSGSMDDRPSISARDYVESLHQNSRATLLYGKNN 262

  Fly    48 VLLKKASAEHIADLN-TSGSLSLVEYSRSIAEMPRRRLLLEWQPNDSI--MIADDSQDQG---DW 106
            ||::...     |:. ..|.|||    ...|::    :.|:|.||..:  .:.|...::.   |:
  Rat   263 VLVQPRD-----DMEAVPGYLSL----HQTADV----MTLKWTPNQLMNGSVGDLDYEKSVYWDY 314

  Fly   107 ALVDRI-------------SGRTRTTSECRAFNTRPIE-PSGGATTRSRVMRAQLEDLSSVEVRH 157
            |:..|:             ||.|............|.. |.||..         |:.||.:|
  Rat   315 AVTIRLEEIVYLHCHQQVDSGGTVVLVSQDGIQRPPFRFPKGGHL---------LQFLSCLE--- 367

  Fly   158 RGQTIRFMRKGANGV--HSE----FFFQHGNADLF--VRSMRDQHLIENAETSRSGGE----VYA 210
                        ||:  |.:    .:.|.|...:|  :|....|...|:..:.:...|    |:.
  Rat   368 ------------NGLLPHGQLDPPLWSQRGKGKVFPKLRKRSPQGSSESTSSDKEDDEATDYVFR 420

  Fly   211 ILTTENQKLKKTFAELDI-------------------------------GQIKASQ-LPRESW-- 241
            |:....|   ..|..||:                               .|.:..| :|..|.
  Rat   421 IIYPGTQ---SEFVTLDLLGSPRPMSVGPAWMMLAAGHSVLVVARGLQWAQTRGCQTVPTRSVKE 482

  Fly   242 ---LPNKLAGI-LGNIPDYVQPPFQRSPKSRPGVLISGDRQTSPDNYQIIGLSGSTNSACSSNGQ 302
               :|..|..: :.|:|...||    ||:.                        |:.|:||.:|.
  Rat   483 QPPMPQDLMDVSMNNLPSLWQP----SPRK------------------------SSCSSCSQSGS 519

  Fly   303 SRGGSA-----EKSP----ADS------------------ELETLNAQDEKIVNNL---PDRQRV 337
            :.|.|.     |::|    .|:                  .|.|:......:||::   ||.. .
  Rat   520 ADGSSTNGCNHERAPLKLLCDNMKYQILSRAFYGWLAYCRHLSTVRTHLSALVNHMIVSPDLP-C 583

  Fly   338 ERGHPLTETQWLEFQTPDGRISDSARIKE-----LIFRGGVVQSLRPEVWKFLLNYYLWSDTHVE 397
            :.|..||.:.|.::      |.||....|     ||:.|||...:|..||.|||.:|.:..|.:|
  Rat   584 DAGQGLTASIWEQY------IQDSTTYPEQELLRLIYYGGVQPEIRRAVWPFLLGHYQFGMTEME 642

  Fly   398 RIERRKQKSIEYYNMKAQWL--------------------------------------AMTTTQE 424
            |.|..:|....|....::||                                      :..:.:.
  Rat   643 RKEVDEQIHACYAQTMSEWLGCEAIVRQRERESHAAALAKCSSGASLDSHLHRMLHRDSTISNES 707

  Fly   425 ANFC--------------------------------GYRERK-------------C--------- 435
            :..|                                |..|.|             |
  Rat   708 SQSCSSGRQNLRLQSDSSSSTQVFESVDEVEQTEAEGRSEEKHPKIPNGNPANGTCSPDSGHPSS 772

  Fly   436 ----------------------------------------------------------------- 435
                                                                             
  Rat   773 HNFSSGLSEHSEPSLSTEDSVLDVQRSLPAVFRPGDSSVEDGQSSEATTSRDEAPREELAVQDSL 837

  Fly   436 ----------------------------------------------------------------- 435
                                                                             
  Rat   838 ESDLLANESLEEFMSIPGSLDVALPEKDGAMMDGWPGEADKHGRADSEDNLSEEPEMESLFPALA 902

  Fly   436 -----------------------------------QIEKDVKRTDRSLQFFAGEDNPNLTLLQGI 465
                                               :|||||:|.|||..:|..   .||..|:.|
  Rat   903 SLAVTSSANNETSPVSSSGVTYSPELLDLYTVNLHRIEKDVQRCDRSYWYFTA---ANLEKLRNI 964

  Fly   466 LMTYVMYNFDLGYVQGMSDLLAPILEIQVNEVDTFWCFVGFMELVFTNFDIDQAGMKTQFAQIRR 530
            :.:|:..:.::||||||.|||||:|.|..:|...|.||...|:.:..||....| |.|.||.:|.
  Rat   965 MCSYIWQHIEIGYVQGMCDLLAPLLVILDDEALAFSCFTELMKRMNQNFPHGGA-MDTHFANMRS 1028

  Fly   531 LIEFANAPLFNYMRSH-DSDNMYFCFRWLLVWYKRELNSEDVLKLWECLWTRLPCPNFH--LLFS 592
            ||:..::.||..|..: |..:.|||:||.|:.:||||..:||..:||.:|......:.|  |..:
  Rat  1029 LIQILDSELFELMHQNGDYTHFYFCYRWFLLDFKRELVYDDVFSVWETIWAAKHVSSAHYVLFIA 1093

  Fly   593 VAILDQETRVIIDSQYEFTEILKHVNELSGNIDVQKTLQVAEGI 636
            :|:::....:|:::..:||:|:|..||::...:.::.||:|..:
  Rat  1094 LALVEVYRDIILENNMDFTDIIKFFNEMAERHNAKQILQLARDL 1137

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_608503.1	TBC	369..598	CDD:214540	88/488 (18%)
Sgsm1	XP_063127295.1	None