Protein Alignment Tbc1d15-17 and Tbc1d25

DIOPT Version :9

• Sequence 1: NP_001259806.1
• Gene: Tbc1d15-17 / 33184
• FlyBaseID: FBgn0031233
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_001159909.1
• Gene: Tbc1d25 / 209815
• MGIID: 2444862
• Length: 723
• Species: Mus musculus
• Alignment Length: 503
• Identity: 140/503 - (27%)
• Similarity: 216/503 - (42%)
• Gaps: 97/503 - (19%)

  Fly   113 SGRTRTTSEC--RAFNTRPIEPSGGATTRSRVMRAQLEDLSSVEVRHRGQTIRFMRKGANGVHSE 175
            ||...|||..  .|.:..| .|.|||...:.|   :.|:...|.||        ::|..:.:..|
Mouse    33 SGGMATTSAASDSACSAAP-PPVGGAQAAAAV---EEEEREVVRVR--------VKKCESFLSPE 85

  Fly   176 F-------------FFQHGNADLFVRSMRDQHLIENAETSRSGGEVYAILTTENQKLKKTFA--- 224
            |             ..||.....|..:.:....|......|.|.|.:..|.:: ..|...||
Mouse    86 FRSFAVDPQITSLDVLQHILIRAFDLNGKKNFGISYLARDRLGQETFLSLLSD-WDLSTAFATAS 149

  Fly   225 ------ELDIGQIKASQLPRESWLPNKLAGILGNIPDYVQPPFQRSPKSRPG--VLISGDRQT-- 279
                  .:||...:.|.| .|.|             |.:      |||...|  ||::..|.:
Mouse   150 KPYLQLRVDIRPSEDSPL-LEDW-------------DII------SPKDVIGSDVLLAEKRSSLT 194

  Fly   280 ---SPDNYQIIGLSGSTNSACSSNGQSRGGSAEKSPADSELETLNAQDEKIVNNLPDRQRVERGH 341
               .|....|:...|.|                .|.....|.....:|.|     |.:.
Mouse   195 TAALPFTQSILSQVGRT----------------LSKVQQVLSWSYGEDVK-----PFKP------ 232

  Fly   342 PLTETQWLEFQTPDGRISDSARIKELIFRGGVVQSLRPEVWKFLLNYYLWSDTHVERIERRKQKS 406
            ||::.::..:...:|::|....::..|:.|||..|||..||::|||.|....|..||::..|:||
Mouse   233 PLSDAEFHTYLNHEGQLSRPEELRLRIYHGGVEPSLRKVVWRYLLNVYPDGLTGRERMDYMKRKS 297

  Fly   407 IEYYNMKAQWLAMTTTQEANFCGYRERKCQIEKDVKRTDRSLQFFAG-EDNPNLTLLQGILMTYV 470
            .||..:|::|......::..|.     :..:.|||.||||:..::|| ||.|:|..|..:|.||.
Mouse   298 REYEQLKSEWAQRVNPEDLEFI-----RSTVLKDVLRTDRAHPYYAGPEDGPHLRALHDLLTTYA 357

  Fly   471 MYNFDLGYVQGMSDLLAPILEIQVNEVDTFWCFVGFMELVFTNFDIDQAGMKTQFAQIRRLIEFA 535
            :.:..:.|.||||||.:|||.:..:|...|.||.|.|:.:..||..|...|.|:||.::.|:..|
Mouse   358 VTHPQVSYCQGMSDLASPILAVMDHEGHAFVCFCGIMKRLAANFHPDGRAMATKFAHLKLLLRHA 422

  Fly   536 NAPLFNYMRSHDSDNMYFCFRWLLVWYKRELNSEDVLKLWECLWTRLP 583
            :...:.|::...:|:::||:||||:..|||...:|.|::.|..|:.||
Mouse   423 DPDFYQYLQEAGADDLFFCYRWLLLELKREFAFDDALRMLEVTWSSLP 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_001259806.1	DUF3548	37..>191	CDD:192931	22/92 (24%)
		TBC	369..598	CDD:214540	82/216 (38%)
Tbc1d25	NP_001159909.1	TBC	260..489	CDD:214540	82/216 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1495285at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920