Protein Alignment Tbc1d15-17 and tbc1d14

DIOPT Version :9

• Sequence 1: NP_001259806.1
• Gene: Tbc1d15-17 / 33184
• FlyBaseID: FBgn0031233
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: XP_004911305.1
• Gene: tbc1d14 / 100489752
• XenbaseID: XB-GENE-991334
• Length: 794
• Species: Xenopus tropicalis
• Alignment Length: 755
• Identity: 145/755 - (19%)
• Similarity: 253/755 - (33%)
• Gaps: 229/755 - (30%)

  Fly    48 VLLKKASAEHIADLNTSGSLSLVEYSRSIAEMPRRRLLLEWQPNDSIMIADDSQDQGDWAL---- 108
            :||..:.|:|....|......:..:|....::|.....|.:.....|.|..:....|.|.|
 Frog    87 LLLAMSQAQHEPQQNGGLHSPVTSWSNMNKDVPTNIRNLGFIEVQDISIESEIPALGKWNLKGAP 151

  Fly   109 ---------------------VDRISGRTRTTSECRAFNTRPIEPSGGATTRSRVMRAQL----- 147
                                 |..:..|..|.........:.:.|:..|....||.:...
 Frog   152 SFGPTEFRPSHHFAASGGSPAVSSVDSRIPTLEIAPPEPVQTLRPNSSAAAHERVFQNSKTISGS 216

  Fly   148 ---EDLSSVEVRH---RGQTIRFMRKGANGVHSEFFFQHGNADLF-------------------- 186
               :.|||.|..|   :..|:  .|.|           :..|.|:
 Frog   217 NGPQSLSSTEPDHVVWKASTL--PRSG-----------YDTAKLYSPTSLNRSDDVSDCSISSLS 268

  Fly   187 -----VRSMRDQHLIENAETSRSGGEVYAILTTENQKLKKTFAELDIGQIKASQLP--RESWLPN 244
                 ..|:.::.:::...||.|.    ||:..||.:..  |:|:.:...|.:...  :||:...
 Frog   269 TDFSTTLSVSNEDIVDFVVTSNSS----AIVALENDETH--FSEVTLNSTKDNSTDGIQESFAQE 327

  Fly   245 -------KLAGILGNI-----------------PDYVQPPFQRSPKSRPGVLISGDRQTSPDNYQ 285
                   |:.|.|.|:                 .|.....|.|.|:       .|:.:|....|
 Frog   328 AEVDKKLKIFGSLSNLFNKNIFARKKSFSVEKTDDLGWKLFNRIPQ-------QGNSRTVSKEY- 384

  Fly   286 IIGLSGSTNSACSSNGQSRGGSAEKSPADSE----------LETLNAQDEKIVNNLP-------D 333
                            :.|.|.|.|||:..:          |.|.....|....|||       .
 Frog   385 ----------------EERIGRASKSPSPKQNVRKSLIFEPLSTTALILEDRPANLPAKPAEEAQ 433

  Fly   334 RQRVERGHPLTETQWLEFQTPDGR-------------ISDSA------------------RIKEL 367
            :.|:|....:.:.:..||:....|             |.::|                  |::::
 Frog   434 KHRLEYEEMVAQAKRREFKDAQRRKKQLEERCKLEESIGNAALTWNTEILPNWETMCCSRRVRDM 498

  Fly   368 IFRGGVVQSLRPEVWKFLLNYYLWSDTHVERIERRKQKSIEYYNM-----KAQWLAMTT-TQEA- 425
            .:: |:..|:|..||...:...| :.||            :.|::     |.:|.:::. ||||
 Frog   499 WWQ-GIPPSVRGRVWSLAIGNEL-NITH------------DLYDICLSRAKDRWKSLSMGTQEAD 549

  Fly   426 ---NFCGYRERKCQIEK---DVKRTDRSLQFFAGEDNPNLTLLQGILMTYVMYNFDLGYVQGMSD 484
               :.....:|:..:|.   |:.||..:|..|. ...|...:|..||..|..|..|:|||||||
 Frog   550 NEDSGLSVADREASLESIKLDISRTFPNLCIFQ-RGGPYHDMLHSILGAYTCYRPDVGYVQGMS- 612

  Fly   485 LLAPILEIQVNEVDTFWCFVGFM----ELVFTNFDIDQAGMKTQFAQIRRLIEFANAP-LFNYMR 544
            .:|.:|.:.::..|.|..|...:    ::.|  |.:|...|.|.||......| .|.| ||.:.:
 Frog   613 FIAAVLILNLDTADAFIAFSNLLNKPCQMAF--FRVDHGLMLTYFAAFEVFFE-ENLPKLFAHFK 674

  Fly   545 SHDSDNMYFCFRWLLVWYKRELNSEDVLKLWECLWTRLPC-PNFHLLFSVA--ILDQETRVIID- 605
            .::.....:...|:...|.:.|..:...::|:..     | .....|||.|  ||    |:..|
 Frog   675 KNNLTPDIYLIDWIFTLYSKSLPLDLACRVWDVF-----CRDGEEFLFSTALGIL----RLFEDI 730

  Fly   606 -SQYEFTEILKHVNELSGNIDVQKTLQVAEGIYLQLKGSE 644
             ::.:|..|.:.:.:|..:::.:........|.:|.:..:
 Frog   731 LTRMDFIHIAQFLTKLPEDLNSEDLFASIAAIQMQSRNKK 770

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_001259806.1	DUF3548	37..>191	CDD:192931	31/203 (15%)
		TBC	369..598	CDD:214540	64/249 (26%)
tbc1d14	XP_004911305.1	TBC	499..731	CDD:214540	66/259 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000