Protein Alignment Tbc1d15-17 and sgsm1

DIOPT Version :10

• Sequence 1: NP_608503.1
• Gene: Tbc1d15-17 / 33184
• FlyBaseID: FBgn0031233
• Length: 715
• Species: Drosophila melanogaster
• Sequence 2: NP_001106422.2
• Gene: sgsm1 / 100127590
• XenbaseID: XB-GENE-6043600
• Length: 1096
• Species: Xenopus tropicalis
• Alignment Length: 607
• Identity: 141/607 - (23%)
• Similarity: 253/607 - (41%)
• Gaps: 125/607 - (20%)

  Fly    69 LVEYSRSIAEMPRRRLLLEWQPNDSIMIADDSQDQGDWALVDRISGRTRTTSECRAFNTRPIEPS 133
            |..|...:.|..||.:       |..:.|...|...:|...:.|..:....|...|.    ::.|
 Frog   575 LGHYQFGMTEEDRREV-------DEQIRACYEQTMAEWLGCEAIVRQREKESHAAAL----LKCS 628

  Fly   134 GGATTRSRVMRAQLEDLSSVEVRHRGQTIRFMRKGANGVHSEFFFQHGNADLFVRSMRDQHLIEN 198
            .||:...::.|          :.||..|:      :|                          |:
 Frog   629 SGASLDIQIQR----------MMHRDSTV------SN--------------------------ES 651

  Fly   199 AETSRSGGEVYAILTTENQKLKKTFAEL-DIGQIKASQLPRESWLPNKLAGILGNIPDYVQPPFQ 262
            :::..|..:.:|.|.:::....:.|..: :..||:|..   |...|.|::.  |.:.:....|..
 Frog   652 SQSCSSDRQNHARLQSDSSSSTQVFESVEEAEQIEARS---EDSKPTKISN--GTVANGTCSPDS 711

  Fly   263 RSPKSRPGVLISGDRQTSPDNYQIIGLSGSTNSACSSNGQS-----RGGSAE-KSPADSELETLN 321
            ..|.||...:.||        |.....|...|::..:|..|     :.|:|| |..|.|::
 Frog   712 GHPSSRNFSITSG--------YSEQSFSTDDNASLETNKNSLYLHMKQGTAEVKKQATSDI---- 764

  Fly   322 AQDEKIVNNLPDRQRVERGHPLTETQWLEFQTPDGRISDSARIKELIFRGGVVQSLRPEVWKFLL 386
                    .||:.:..| ..|:.::.       ||.::.:..:.:.:........|.|:....:|
 Frog   765 --------ILPENKTAE-VLPIQDSL-------DGEVTANESLDDFLSITESTDDLLPDKETAVL 813

  Fly   387 NYY-LWSDTHVER-----IERRKQKSIEYYNMKAQWLAMTTTQEANFCG---------------- 429
            :.. .|.|:..|:     .|....:..|..::..| |......:|..|.
 Frog   814 SVVETWPDSEAEKESLVGSEDNLSEEPEMESLYPQ-LDSLVVIDATVCEMSPVSSTGVTYSQELL 877

  Fly   430 --YRERKCQIEKDVKRTDRSLQFFAGEDNPNLTLLQGILMTYVMYNFDLGYVQGMSDLLAPILEI 492
              |.....:|||||:|.||:..:|.   ..||..|:.::.:||..:.::||||||.|||||:|.|
 Frog   878 DMYTINLHRIEKDVQRCDRNYWYFT---PANLEKLRNVMCSYVWQHIEIGYVQGMCDLLAPLLVI 939

  Fly   493 QVNEVDTFWCFVGFMELVFTNFDIDQAGMKTQFAQIRRLIEFANAPLFNYMRSH-DSDNMYFCFR 556
            ..:|...|.||...|:.:..||....| |.|.||.:|.||:..::.||..|..: |..:.|||:|
 Frog   940 LDDEAKAFSCFTELMKRMNQNFPHGGA-MDTHFANMRSLIQILDSELFELMHQNGDYTHFYFCYR 1003

  Fly   557 WLLVWYKRELNSEDVLKLWECLWT--RLPCPNFHLLFSVAILDQETRVIIDSQYEFTEILKHVNE 619
            |.|:.:||||..:||..:||.:|.  .:...:|.|..::|:::....:|:::..:||:|:|..||
 Frog  1004 WFLLDFKRELVYDDVFSVWETIWAAKHISSAHFVLFIALALVEVYRDIILENNMDFTDIIKFFNE 1068

  Fly   620 LSGNIDVQKTLQVAEGIYLQLK 641
            ::...:::..|::|:.:..:::
 Frog  1069 MAERHNIKHILKLAQDLVYKVQ 1090

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbc1d15-17	NP_608503.1	TBC	369..598	CDD:214540	77/255 (30%)
sgsm1	NP_001106422.2	RUN_SGSM1	20..196	CDD:439065
		PH_RUTBC	254..424	CDD:275431
		TBC	872..1053	CDD:214540	65/184 (35%)