DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11617 and mkxa

DIOPT Version :9

Sequence 1:	NP_001245817.1	Gene:	CG11617 / 33183	FlyBaseID:	FBgn0031232	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001092203.2	Gene:	mkxa / 799136	ZFINID:	ZDB-GENE-080513-1	Length:	349	Species:	Danio rerio

Alignment Length:	302	Identity:	83/302 - (27%)
Similarity:	127/302 - (42%)	Gaps:	56/302 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KSTRPKRNRRHSRRAWPPEEELHPASRATKRLFTPDIKRMLKDWLIRRRENPYPSREEKKQLAAE 67
            |.:...|:||...|.       :|.....||....|:.|.||.||.:.|:||||::.||..||..
Zfish    48 KDSSAIRHRRSGSRQ-------NPGKVRHKRQALQDMARPLKQWLYKHRDNPYPTKTEKILLALG 105

  Fly    68 TGLTYTQICNWFANWRRKLKNSEREKAKKSWGHLIKNYNHNARGNVEQFSISSEDSIWEEEMHSC 132
            :.:|..|:.|||||.||:|||:.|: ...||...||.||...:||.|:.|:||:|        ||
Zfish   106 SQMTLVQVSNWFANARRRLKNTVRQ-PDLSWALRIKLYNKYVQGNAERLSVSSDD--------SC 161

  Fly   133 PAEDDEGDDNEEFSSHSTGSDGNANNEPSSP-YKPILFVGSAGLTERISAQTGGK--------TK 188
                  .||.:..:....|       |.|.| |:.::.....|:...:.|.:...        .|
Zfish   162 ------SDDADPATRAQVG-------EFSKPMYQSVIKKEGGGMGAGLRAASDASLADDYVSPPK 213

  Fly   189 YKHQMMEKYMRDSSTAKTTSQQGTQLNKWLESAAKFTPDRNNYHIEWNMTRQKASSNSSCGQAIF 253
            ||..::.:|:.| |........|....:....:..|:.:      |::......||:.:....|:
Zfish   214 YKSSLLHRYLND-SLRHVMGANGVMDARKRNHSGSFSSN------EYDEDLLSPSSSEAEANFIY 271

  Fly   254 TTDV--SGAGRGGRWMLHHKD---------ELEAAEALANLA 284
            .|:.  .|:.:..|.:...|.         |:.||.|..|||
Zfish   272 RTETVEHGSNKCDRSLQKEKGQRKDETYWREINAAMAPTNLA 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11617	NP_001245817.1	Homeobox_KN	46..84	CDD:283551	18/37 (49%)
mkxa	NP_001092203.2	Homeobox_KN	84..123	CDD:283551	19/38 (50%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586393
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	100	1.000	Inparanoid score	I4993
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D283391at33208
OrthoFinder	1	1.000	-	-		FOG0007188
OrthoInspector	1	1.000	-	-		otm24480
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11211
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5569
SonicParanoid	1	1.000	-	-		X4615
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.930