DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11617 and IRX3

DIOPT Version :9

Sequence 1:	NP_001245817.1	Gene:	CG11617 / 33183	FlyBaseID:	FBgn0031232	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	XP_005256196.1	Gene:	IRX3 / 79191	HGNCID:	14360	Length:	529	Species:	Homo sapiens

Alignment Length:	148	Identity:	45/148 - (30%)
Similarity:	70/148 - (47%)	Gaps:	11/148 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 HSRRAWPPEEELHPASRATKRLFTPDIKRMLKDWLIRRRENPYPSREEKKQLAAETGLTYTQICN 77
            |...|:.|..:......:..:..|.:....||.||...|:||||::.||..||..|.:|.||:..
Human   112 HPHPAFYPYGQYQFGDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVST 176

  Fly    78 WFANWRRKLKNSEREKAKKSWGHLIK-NYNHNARGNVEQFSISSEDSIWEEEMHSCPAEDDEGDD 141
            ||||.||:||    ::.|.:|....: :...||.|:..:.....||.  |:.......|::|...
Human   177 WFANARRRLK----KENKMTWAPRSRTDEEGNAYGSEREEEDEEEDE--EDGKRELELEEEELGG 235

  Fly   142 NEEFSSHSTGSDGNANNE 159
            .||    .||.:|.|:::
Human   236 EEE----DTGGEGLADDD 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11617	NP_001245817.1	Homeobox_KN	46..84	CDD:283551	19/37 (51%)
IRX3	XP_005256196.1	Homeobox_KN	145..184	CDD:283551	20/38 (53%)
IRX3	XP_005256196.1	IRO	344..359	CDD:214716
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900