Protein Alignment CG11617 and IRX6

DIOPT Version :9

• Sequence 1: NP_001245817.1
• Gene: CG11617 / 33183
• FlyBaseID: FBgn0031232
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_077311.2
• Gene: IRX6 / 79190
• HGNCID: 14675
• Length: 446
• Species: Homo sapiens
• Alignment Length: 238
• Identity: 64/238 - (26%)
• Similarity: 90/238 - (37%)
• Gaps: 63/238 - (26%)

  Fly    23 ELHPASRATKRLFTPDIKRMLKDWLIRRRENPYPSREEKKQLAAETGLTYTQICNWFANWRRKL- 86
            ||..|.|  ::..|.:....||.||...|:||||::.||..||..|.:|.||:..||||.||:|
Human   143 ELSGAGR--RKNATRETTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLK 205

  Fly    87 -----------KNSEREKA----KKSWGHLIKN-----YNHNARGNVEQFSISSEDSIWEEEMHS 131
                       |..|..||    :.|.|.|..:     .:..|||    ..:|..:.:.|||...
Human   206 KENKMTWAPKNKGGEERKAEGGEEDSLGCLTADTKEVTASQEARG----LRLSDLEDLEEEEEEE 266

  Fly   132 CPAEDDE-----GDDNEEFSSHSTGSDGN---------------------ANNEPSSPYKPILFV 170
            ..|||:|     ||...||...:....|.                     :.|:||...:
Human   267 EEAEDEEVVATAGDRLTEFRKGAQSLPGPCAAAREGRLERRECGLAAPRFSFNDPSGSEE----- 326

  Fly   171 GSAGLTERISAQTGGKTKYKHQMMEKYMRDSSTAKTTSQQGTQ 213
                 .:.:||:||......|....:..|..|.|.|.:....:
Human   327 -----ADFLSAETGSPRLTMHYPCLEKPRIWSLAHTATASAVE 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11617	NP_001245817.1	Homeobox_KN	46..84	CDD:283551	19/37 (51%)
IRX6	NP_077311.2	Homeobox_KN	164..203	CDD:283551	20/38 (53%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	208..273		17/68 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	362..394		0/3 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900