Protein Alignment CG11617 and Irx6

DIOPT Version :10

• Sequence 1: NP_608502.1
• Gene: CG11617 / 33183
• FlyBaseID: FBgn0031232
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_071873.2
• Gene: Irx6 / 64379
• MGIID: 1927642
• Length: 439
• Species: Mus musculus
• Alignment Length: 318
• Identity: 77/318 - (24%)
• Similarity: 115/318 - (36%)
• Gaps: 93/318 - (29%)

  Fly    23 ELHPASRATKRLFTPDIKRMLKDWLIRRRENPYPSREEKKQLAAETGLTYTQICNWFANWRRKLK 87
            ||..|.|  ::..|.:....||.||...|:||||::.||..||..|.:|.||:..||||.||:||
Mouse   140 ELSSAGR--RKNATRESTSALKAWLHEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLK 202

  Fly    88 NSEREKAKKSWGHLIKNYNHNARGNVEQFSISSEDSI--------------------------WE 126
                ::.|.:|..  ||     :|..|:.:.|.|||:                          .|
Mouse   203 ----KENKMTWAP--KN-----KGGEERKADSGEDSLGCLNGDTKDATASQEARGLRLSDLEDLE 256

  Fly   127 EEMHSCPAEDDEGDDNEEFSSHSTGSDGNANNEP--------------------SSPYKPILFVG 171
            ||     .|::|.::....|:....:|...:.:|                    ..|........
Mouse   257 EE-----EEEEEAEEEAAVSAARRLADFQKSTQPLPAPCAAAQERCLESRECGLGLPRFSFTEAP 316

  Fly   172 SAGLTERISAQTGGKTKYKHQMMEKYMRDSSTAKTTSQQGTQLNKWLESAAKFTPDRNNYHIEWN 236
            .:|..:.|:|:.||.|...|.......|..|.|.|.:....:       :|..||.|........
Mouse   317 QSGEADFITAEPGGPTMILHYPSGHKPRIWSLAHTAAASAVE-------SAPSTPPRAQSPECHM 374

  Fly   237 MTRQKASSNSSCGQAIFTTDVSGAGRGGRWMLHHKDELEAAEALANLAF-------NC 287
            :.||.    ||..:.:...|..|           :::..||:|..|..|       ||
Mouse   375 IPRQP----SSIRRLLVPRDSEG-----------EEDSPAAKAFGNSTFTLQGLPLNC 417

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11617	NP_608502.1	homeodomain	29..90	CDD:238039	27/60 (45%)
Irx6	NP_071873.2	COG5576	<142..232	CDD:227863	38/102 (37%)
		Homeobox_KN	162..200	CDD:428673	19/37 (51%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	205..270		15/76 (20%)