Protein Alignment CG11617 and PKNOX2

DIOPT Version :10

• Sequence 1: NP_608502.1
• Gene: CG11617 / 33183
• FlyBaseID: FBgn0031232
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_001369252.1
• Gene: PKNOX2 / 63876
• HGNCID: 16714
• Length: 472
• Species: Homo sapiens
• Alignment Length: 138
• Identity: 40/138 - (28%)
• Similarity: 61/138 - (44%)
• Gaps: 40/138 - (28%)

  Fly    42 MLKDWLIRRRENPYPSREEKKQLAAETGLTYTQICNWFANWRRKL-------KNSE-REKAKKSW 98
            :::.||.:...:|||:.:||:|:||:|.||..|:.|||.|.||::       .|.: ..||||
Human   302 IMRSWLFQHLMHPYPTEDEKRQIAAQTNLTLLQVNNWFINARRRILQPMLDASNPDPAPKAKK-- 364

  Fly    99 GHLIKNY---------NHNARGNVEQ------------------FSISSEDSIWEEEMHSCPAED 136
               ||:.         |..|.|.::|                  .|:||:.:....:.....|.|
Human   365 ---IKSQHRPTQRFWPNSIAAGVLQQQGGAPGTNPDGSINLDNLQSLSSDSATMAMQQAMMAAHD 426

  Fly   137 DEGDDNEE 144
            |..|..||
Human   427 DSLDGTEE 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11617	NP_608502.1	homeodomain	29..90	CDD:238039	21/54 (39%)
PKNOX2	NP_001369252.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..62
		PLN02983	<3..>66	CDD:215533
		Meis_PKNOX_N	96..181	CDD:465140
		Homeobox_KN	307..345	CDD:428673	18/37 (49%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	351..371		7/24 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	386..405		1/18 (6%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	422..472		6/13 (46%)