Protein Alignment CG11617 and IRX4

DIOPT Version :10

• Sequence 1: NP_608502.1
• Gene: CG11617 / 33183
• FlyBaseID: FBgn0031232
• Length: 294
• Species: Drosophila melanogaster
• Sequence 2: NP_001265562.1
• Gene: IRX4 / 50805
• HGNCID: 6129
• Length: 545
• Species: Homo sapiens
• Alignment Length: 192
• Identity: 57/192 - (29%)
• Similarity: 76/192 - (39%)
• Gaps: 37/192 - (19%)

  Fly     1 MDKSTRPKRNRRHSRRAWPPEEELHPASRATKRLFTPDIKRMLKDWLIRRRENPYPSREEKKQLA 65
            ||..||.|.                 |:|.|        ...||.||...|:||||::.||..||
Human   166 MDSGTRRKN-----------------ATRET--------TSTLKAWLQEHRKNPYPTKGEKIMLA 205

  Fly    66 AETGLTYTQICNWFANWRRKLKNSEREKAKKSWGHLIKNYNHN---ARGNVEQFSISSEDSIWEE 127
            ..|.:|.||:..||||.||:||    ::.|.:|....|..:..   |.|..|:   ..|:...||
Human   206 IITKMTLTQVSTWFANARRRLK----KENKMTWPPRNKCADEKRPYAEGEEEE---GGEEEAREE 263

  Fly   128 EMHSCPAEDDEGDDNEEFS-SHSTGSDGNANNEPSSPYKPILFVGSAGLTERISAQTGGKTK 188
            .:.|....:..|.:.:|.. |.....|......|:...||.......|| ||:.|...|..|
Human   264 PLKSSKNAEPVGKEEKELELSDLDDFDPLEAEPPACELKPPFHSLDGGL-ERVPAAPDGPVK 324

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11617	NP_608502.1	homeodomain	29..90	CDD:238039	27/60 (45%)
IRX4	NP_001265562.1	Homeobox_KN	187..225	CDD:428673	19/37 (51%)