DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG11617 and MEIS2

DIOPT Version :9

Sequence 1:NP_001245817.1 Gene:CG11617 / 33183 FlyBaseID:FBgn0031232 Length:294 Species:Drosophila melanogaster
Sequence 2:NP_733775.1 Gene:MEIS2 / 4212 HGNCID:7001 Length:477 Species:Homo sapiens


Alignment Length:59 Identity:27/59 - (45%)
Similarity:38/59 - (64%) Gaps:1/59 - (1%)


- Green bases have known domain annotations that are detailed below.


  Fly    29 RATKRLFTPDI-KRMLKDWLIRRRENPYPSREEKKQLAAETGLTYTQICNWFANWRRKL 86
            |..||...|.: ..:::.||.:...:||||.|:|||||.:||||..|:.|||.|.||::
Human   276 RQKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRI 334

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG11617NP_001245817.1 Homeobox_KN 46..84 CDD:283551 21/37 (57%)
MEIS2NP_733775.1 Required for interaction with PBX1. /evidence=ECO:0000250 71..191
Meis_PKNOX_N 110..194 CDD:406806
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 193..283 3/6 (50%)
Homeobox_KN 294..333 CDD:399131 22/38 (58%)
Interaction with DNA. /evidence=ECO:0000305|PubMed:26550823, ECO:0000305|Ref.16 299..333 20/33 (61%)
PAT1 <335..>463 CDD:401645 27/59 (46%)
Transcriptional activation domain 340..477
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0773
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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