DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11617 and irx3

DIOPT Version :9

Sequence 1:	NP_001245817.1	Gene:	CG11617 / 33183	FlyBaseID:	FBgn0031232	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001001216.1	Gene:	irx3 / 407888	XenbaseID:	XB-GENE-480486	Length:	448	Species:	Xenopus tropicalis

Alignment Length:	228	Identity:	57/228 - (25%)
Similarity:	92/228 - (40%)	Gaps:	28/228 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 HSRRAWPPEEELHPASRATKRLFTPDIKRMLKDWLIRRRENPYPSREEKKQLAAETGLTYTQICN 77
            |...|:.|..:......:..:..|.:....||.||...|:||||::.||..||..|.:|.||:..
Frog    93 HPHAAFYPYGQYQFGDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVST 157

  Fly    78 WFANWRRKLK---------NSEREKAKKSWGHLIKNYNHNARGNVEQFSISSEDSIWEEEMHSCP 133
            ||||.||:||         .|..::...::|...:...|.....::..:|.:||...:|::.. |
Frog   158 WFANARRRLKKENKMTWAPRSRTDEEGNAYGSDHEEDKHEDDEEIDLENIDTEDIESKEDLDD-P 221

  Fly   134 AEDDEGDDNEEFSSHSTGSDGNAN-NEPSSPYKPILFVGSAGLTERISAQTGGKTKYKHQMMEKY 197
            ..|...|...:..|.|..|||..: |.|.               :|:.....|:.:..::..:..
Frog   222 DTDIHSDSKTDARSDSEASDGFEDLNAPE---------------DRLLKSVVGQRQVLNEEPQDK 271

  Fly   198 MRDSSTAKTTSQQGTQLNKWLESAAKFTPDRNN 230
            ...||.||.:.....|:.  |:......|..||
Frog   272 CALSSDAKASQPACEQIK--LDRIPSSPPLENN 302

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11617	NP_001245817.1	Homeobox_KN	46..84	CDD:283551	19/37 (51%)
irx3	NP_001001216.1	Homeobox_KN	126..165	CDD:310480	20/38 (53%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	171..250		16/79 (20%)
		IRO	304..321	CDD:214716
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	387..410
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000