DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG11617 and Tgif2

DIOPT Version :9

Sequence 1:	NP_001245817.1	Gene:	CG11617 / 33183	FlyBaseID:	FBgn0031232	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_775572.1	Gene:	Tgif2 / 228839	MGIID:	1915299	Length:	237	Species:	Mus musculus

Alignment Length:	197	Identity:	48/197 - (24%)
Similarity:	77/197 - (39%)	Gaps:	55/197 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 KRNRRHSRRAWPPEEELHPASRATKRLFTPDIKRMLKDWLIRRRENPYPSREEKKQLAAETGLTY 72
            ||.||.:.    |:|.:                ::|:|||...|.|.|||.:||..|:.:|.|:.
Mouse    18 KRKRRGNL----PKESV----------------KILRDWLYLHRYNAYPSEQEKLSLSGQTNLSV 62

  Fly    73 TQICNWFANWRRK-LKNSEREKAKKSWGHLIKNYNHNA------RGNVEQF---SISSEDSIWEE 127
            .||||||.|.||: |.:..|:..|......|......|      ||:....   |:.:..::...
Mouse    63 LQICNWFINARRRLLPDMLRKDGKDPNQFTISRRGGKASDVALPRGSSPSLLAVSVPAPTNMLSL 127

  Fly   128 EMHSCPAEDDEGDDNEEFSSHSTGSDGNANNEPSSPYKPI-------LFVGSAGLTERISAQTGG 185
            .:.|.|....:|:                  :|::|:..:       |...::.||....|:.|.
Mouse   128 SVCSMPLHSGQGE------------------KPAAPFPQVELESPKALVTPASTLTLLTRAEAGS 174

  Fly   186 KT 187
            .|
Mouse   175 PT 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11617	NP_001245817.1	Homeobox_KN	46..84	CDD:283551	19/37 (51%)
Tgif2	NP_775572.1	Homeobox_KN	36..75	CDD:368670	20/38 (53%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	87..106		2/18 (11%)
		Repressive function	103..237		14/92 (15%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	171..196		2/6 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	212..237
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900