DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11617 and Irx3

DIOPT Version :9

Sequence 1:	NP_001245817.1	Gene:	CG11617 / 33183	FlyBaseID:	FBgn0031232	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_001240751.1	Gene:	Irx3 / 16373	MGIID:	1197522	Length:	522	Species:	Mus musculus

Alignment Length:	148	Identity:	46/148 - (31%)
Similarity:	70/148 - (47%)	Gaps:	11/148 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 HSRRAWPPEEELHPASRATKRLFTPDIKRMLKDWLIRRRENPYPSREEKKQLAAETGLTYTQICN 77
            |...|:.|..:......:..:..|.:....||.||...|:||||::.||..||..|.:|.||:..
Mouse   115 HPHPAFYPYGQYQFGDPSRPKNATRESTSTLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVST 179

  Fly    78 WFANWRRKLKNSEREKAKKSWGHLIK-NYNHNARGNVEQFSISSEDSIWEEEMHSCPAEDDEGDD 141
            ||||.||:||    ::.|.:|....: :...||.|:..:.....||.  ||.......|::|...
Mouse   180 WFANARRRLK----KENKMTWAPRSRTDEEGNAYGSEREEEDEEEDE--EESKRELEMEEEELAG 238

  Fly   142 NEEFSSHSTGSDGNANNE 159
            .||    .||.:|.|:::
Mouse   239 EEE----DTGGEGLADDD 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11617	NP_001245817.1	Homeobox_KN	46..84	CDD:283551	19/37 (51%)
Irx3	NP_001240751.1	Homeobox_KN	148..187	CDD:283551	20/38 (53%)
Irx3	NP_001240751.1	IRO	345..362	CDD:214716
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900