DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11617 and IRX5

DIOPT Version :9

Sequence 1:	NP_001245817.1	Gene:	CG11617 / 33183	FlyBaseID:	FBgn0031232	Length:	294	Species:	Drosophila melanogaster
Sequence 2:	NP_005844.4	Gene:	IRX5 / 10265	HGNCID:	14361	Length:	483	Species:	Homo sapiens

Alignment Length:	133	Identity:	42/133 - (31%)
Similarity:	59/133 - (44%)	Gaps:	20/133 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 ATKRLFTPDIKRMLKDWLIRRRENPYPSREEKKQLAAETGLTYTQICNWFANWRRKLKNSEREKA 94
            |.::..|.|....||.||...|:||||::.||..||..|.:|.||:..||||.||:||    ::.
Human   115 AYRKNATRDATATLKAWLNEHRKNPYPTKGEKIMLAIITKMTLTQVSTWFANARRRLK----KEN 175

  Fly    95 KKSWGHLIKNYNHNARGNVEQFSISSEDSIWEEEMHSCPAEDDEGDDNEEFSSHSTGSDGNANNE 159
            |.:|         ..|..       |||...||.:.....::||....|:.........|.|..:
Human   176 KMTW---------TPRNR-------SEDEEEEENIDLEKNDEDEPQKPEDKGDPEGPEAGGAEQK 224

  Fly   160 PSS 162
            .:|
Human   225 AAS 227

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11617	NP_001245817.1	Homeobox_KN	46..84	CDD:283551	19/37 (51%)
IRX5	NP_005844.4	Homeobox_KN	131..170	CDD:283551	20/38 (53%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	177..392		13/67 (19%)
		IRO	327..344	CDD:214716
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	423..442
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0773
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900