DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG3436 and WDR43

DIOPT Version :9

Sequence 1:NP_001285543.1 Gene:CG3436 / 33180 FlyBaseID:FBgn0031229 Length:347 Species:Drosophila melanogaster
Sequence 2:NP_055946.1 Gene:WDR43 / 23160 HGNCID:28945 Length:677 Species:Homo sapiens


Alignment Length:239 Identity:55/239 - (23%)
Similarity:95/239 - (39%) Gaps:75/239 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly    15 EAKRSKNDLMAYTNRDKALLESGVRRTSNLQAPIMQLEGHEGEIF-----TAEFHPEGELLLSSG 74
            :.|:.|::.:..:|                |..::.|....|.|.     ..|.|.:   |:|.|
Human    79 QRKKRKSEAVGMSN----------------QTDLLALGTAVGSILLYSTVKGELHSK---LISGG 124

  Fly    75 FDRQIYIWQVYEDCENVMAMSGHSGAVMEAHFTPDGSHIFTCSTDKTLAFWDIATGQRQRRFKGH 139
            .|.::...|.::|          ||.            :::||.||.:..|::.|.:.:.::||.
Human   125 HDNRVNCIQWHQD----------SGC------------LYSCSDDKHIVEWNVQTCKVKCKWKGD 167

  Fly   140 GNFVNSVQGSRRGQQLLCSGSDDRTIKIWDARKKHA-AHTLESPFQVTAVCF------------- 190
            .:.|:|:..|..|:.||.:|   ||||:|....|.. .|.......|:::.|             
Human   168 NSSVSSLCISPDGKMLLSAG---RTIKLWVLETKEVYRHFTGHATPVSSLMFTTIRPPNESQPFD 229

  Fly   191 GDTGEQVISGGI-DNEVKIWDIR-----KQAVLHHLRGHSDTIT 228
            |.||...:||.: |..:.:|.:|     |.||:      |.|:|
Human   230 GITGLYFLSGAVHDRLLNVWQVRSENKEKSAVM------SFTVT 267

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG3436NP_001285543.1 WD40 <19..346 CDD:225201 54/235 (23%)
WD40 50..342 CDD:238121 51/204 (25%)
WD40 repeat 58..96 CDD:293791 9/42 (21%)
WD40 repeat 102..138 CDD:293791 6/35 (17%)
WD40 repeat 143..180 CDD:293791 14/37 (38%)
WD40 repeat 186..221 CDD:293791 12/53 (23%)
WD40 repeat 227..267 CDD:293791 1/2 (50%)
WD40 repeat 277..313 CDD:293791
WD40 repeat 319..342 CDD:293791
WDR43NP_055946.1 WD 1 11..51
WD40 19..272 CDD:295369 55/239 (23%)
WD40 <19..217 CDD:225201 40/181 (22%)
WD40 repeat 19..57 CDD:293791
WD 2 57..119 9/55 (16%)
WD40 repeat 63..124 CDD:293791 11/63 (17%)
WD 3 124..163 12/60 (20%)
WD40 repeat 129..165 CDD:293791 10/57 (18%)
WD 4 166..205 15/41 (37%)
WD40 repeat 172..205 CDD:293791 13/35 (37%)
WD 5 207..259 10/51 (20%)
WD40 repeat 211..262 CDD:293791 12/50 (24%)
WD 6 267..309 1/1 (100%)
WD40 repeat 271..320 CDD:293791
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 414..445
Utp12 474..570 CDD:281932
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 582..677
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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