DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3436 and B0280.9

DIOPT Version :9

Sequence 1:	NP_001285543.1	Gene:	CG3436 / 33180	FlyBaseID:	FBgn0031229	Length:	347	Species:	Drosophila melanogaster
Sequence 2:	NP_498555.1	Gene:	B0280.9 / 175994	WormBaseID:	WBGene00015104	Length:	429	Species:	Caenorhabditis elegans

Alignment Length:	297	Identity:	56/297 - (18%)
Similarity:	106/297 - (35%)	Gaps:	77/297 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 TKRPNNSVILAQEAKRSKNDLMAYTNRDKALLESGV--RRTSNLQAP------------------ 47
            :|.|.:|:.:|.:.    :.::..::|.:.|::..:  |..:.|:.|
Worm   164 SKFPIDSLEIADKG----HSVICSSSRKEYLMQYNMETREVTQLKPPNTVPKQGIRLFAISHDSQ 224

  Fly    48 IMQLEGHEGEIF----TAEFH--------PEGELLLSSGFDRQIYIWQVYEDCENVMAMSGHSGA 100
            .:.:.||...|:    |:..|        ...|:.......|:  ||.:.|..:.|:|..|..|.
Worm   225 FLAIAGHNSHIYVLHATSMEHITTISLPANASEIKFFPSHSRE--IWIICETGQIVIANIGLPGT 287

  Fly   101 VMEAH-FTPDGSHIFTCSTDKTLAFWDIATGQRQRRFKGHGNFVNSVQGSRRGQQLLCSGSDDRT 164
            ....| ||.||:...|     |||            ...||::.  ..||..|...:.||:|.|.
Worm   288 KSSQHTFTDDGAVHGT-----TLA------------ISQHGDYF--ATGSDTGIVNVYSGNDCRN 333

  Fly   165 -------IKIWDARKKHAAHTLESPFQVTAVCFGDTGEQVISGGIDNEVKIWDIRKQAVLHHLRG 222
                   ..:.:.....::....|..|:.|:|         |...||.:::..:..|....:...
Worm   334 STNPRPLFNVSNLVTAVSSIAFNSDAQLMAIC---------SNVKDNHLRLVHVASQTTFKNFPE 389

  Fly   223 HSDTITG---MSLSPEGDFILTNAMDNTLRVWDVRPY 256
            .:..:|.   :..||.|.::.....|..|.|:::..:
Worm   390 RNGKVTHARCVEFSPNGGYMAVGNDDGRLHVFEIHHF 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3436	NP_001285543.1	WD40	<19..346	CDD:225201	52/281 (19%)
		WD40	50..342	CDD:238121	47/230 (20%)
		WD40 repeat	58..96	CDD:293791	10/49 (20%)
		WD40 repeat	102..138	CDD:293791	9/36 (25%)
		WD40 repeat	143..180	CDD:293791	7/43 (16%)
		WD40 repeat	186..221	CDD:293791	6/34 (18%)
		WD40 repeat	227..267	CDD:293791	7/33 (21%)
		WD40 repeat	277..313	CDD:293791
		WD40 repeat	319..342	CDD:293791
B0280.9	NP_498555.1	WD40	<66..424	CDD:225201	56/293 (19%)
		WD40 repeat	122..195	CDD:293791	6/34 (18%)
		WD40	167..423	CDD:295369	55/289 (19%)
		WD40 repeat	168..207	CDD:293791	6/42 (14%)
		WD40 repeat	201..251	CDD:293791	7/49 (14%)
		WD40 repeat	258..296	CDD:293791	10/39 (26%)
		WD40 repeat	303..343	CDD:293791	13/58 (22%)
		WD40 repeat	350..388	CDD:293791	8/46 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910