Protein Alignment CG42399 and che-12

DIOPT Version :9

• Sequence 1: NP_608498.3
• Gene: CG42399 / 33176
• FlyBaseID: FBgn0259818
• Length: 1655
• Species: Drosophila melanogaster
• Sequence 2: NP_001256204.1
• Gene: che-12 / 179433
• WormBaseID: WBGene00000491
• Length: 1282
• Species: Caenorhabditis elegans
• Alignment Length: 1138
• Identity: 216/1138 - (18%)
• Similarity: 375/1138 - (32%)
• Gaps: 428/1138 - (37%)

  Fly   572 NISPKVPHKQIEVLHNLQRDPSPRSQRRSEDMDGNGDGKALHATGNPSSSPTQPLISRTRSASTM 636
            |:||:......::..|:|.:       .:|...|:|   .|.|:..|.|...:    |.|.....
 Worm   218 NLSPEKREVLEQITANVQVE-------HTESKAGSG---VLRASAKPQSGGER----RLRFGIVP 268

  Fly   637 SPVSPATPKSWEDLDIVNLKTLLELRSGDWRNRLMGIGQLELALS--SSSNLALVQPYLDSLLRT 699
            |.|.....   ||.|.              ..|:.|:.:::..:.  :...:|.:.|:|.|.| .
 Worm   269 SLVCALIA---EDTDA--------------NQRISGLEKMKQVVDQITPEEIARLVPHLHSYL-L 315

  Fly   700 LLSSERHFEVSDLKRELLVNLISRLPLD-----------NLEERTPQILSGLCRQ-GNAGANRVC 752
            :||:    .:.||..:::|     |.||           ::|....|.::.:.:. ||  ...|.
 Worm   316 MLSN----VLEDLNFKVVV-----LALDIVRATGHHLKGHMEAHIQQFVNLVAKHFGN--QKSVI 369

  Fly   753 K--------ALMQRLPAGTIVAKLTSPEFLHAKSSKFRDHALQMSIFALMTFPGTCFDISLLTTQ 809
            |        .|.|.:...|:...|.  .||..|:|:.|:..:.:...:|||...:.|::..|...
 Worm   370 KQIIMMTFMELFQNINPKTVGGCLR--VFLENKNSRVREEVINIYTASLMTISPSKFNLQPLVNI 432

  Fly   810 AVYSLLNRKRRVRQAALEVLAVLADISSIK-EVLTIVSETTDGVELGPMVLEATSVRLSRLQLPI 873
            .|....:.|:|||.||.|.|:|||.:.:.| |::.......:..:....:.||.:.|:.|..||.
 Worm   433 LVPMFHDVKKRVRLAAFEQLSVLAYLLNGKTEIIMKPVRDFEQDQNSRGLTEAVTARIRRQVLPR 497

  Fly   874 VTPDSGVLFVFNQTDPPGARRF-----------GADVDWIHQGEGSASPNTIKRRRMRAASSQRN 927
            :..|.    :...:.||....|           .||:.||...
 Worm   498 IRYDG----LIEYSTPPMMDSFDLAEAEMSLPSNADLSWIVSN---------------------- 536

  Fly   928 VLGGAEAKNKNDPFPSFRQVNESVHRHSFHSPPETLDMASPINDFSQRLSFGAKTNGGSQSFIER 992
              ||.|.    |||                  ..|:   |||:
 Worm   537 --GGVEP----DPF------------------ERTM---SPIS---------------------- 552

  Fly   993 RFLAKACSDTSMDGRSTDSTTTTCSSGSATDSFIQLTSRTGGRLAGPNSRFPTMNQHADFVNNFM 1057
                                                       |||   ...|:.::
 Worm   553 -------------------------------------------LAG---NLATIRRN-------- 563

  Fly  1058 RSMQRGSKSHSVERPNYPKVSYSIPKSQQMIRKKFQHKDSFTKLGDEPPGQSIENNKFNESQRRK 1122
            |.:|:..::   |:|     |:|:|                     :.|.|...    :::||..
 Worm   564 RVIQQQGQA---EKP-----SFSLP---------------------QQPAQQAS----HQAQRLP 595

  Fly  1123 SGISTDHMESLDSKCADV--------IKSVDTETEVNGMTNGSPISASSTSYSQKS---TASAKS 1176
            :||...| |:.::...|:        :||.|:.....|....:|.|::|:..:.|.   :.|.||
 Worm   596 NGIEKSH-ETSENSSLDIGQRIVMTRMKSDDSFVRRQGSAASNPNSSTSSWEAPKRPPISPSEKS 659

  Fly  1177 SISQNEMGKRPFSSTGLWNDCKVEVLNREHNPNEAFGELVVDAIKVQTESEPTAHEELLKLNGSL 1241
            |||..                |.|| |..|                           ::| .|:|
 Worm   660 SISAT----------------KKEV-NNNH---------------------------IVK-KGNL 679

  Fly  1242 NSLHSKTESIKTQLEETTPQLSRAQSVKSLLIEEDIESSNSFVVVEEVENE----LESSPAKGEE 1302
            .|:.::::   |.|.|...:                         ||:||:    .:..|||...
 Worm   680 KSMRARSD---TNLSEDHGE-------------------------EEMENDPPRSFDDRPAKASG 716

  Fly  1303 EVPLQEELATPVKATKLENHTFGPKLVPTHDEIVIHSRSVSLDSLYGTRPASKQGSMDTSTSTAE 1367
            :...|:               |...:||
 Worm   717 QYSFQD---------------FDAAIVP------------------------------------- 729

  Fly  1368 NTSQTGSQIGNTSVPAKAQHTPLKHKSKTSYFLRAQRRISPSKQPIKMSQAELFPQNMVRFDRPR 1432
             :|.....|.:.|:|. ..|.||||.     ..:.|:||:.:...::..|.:. .:::.:..|..
 Worm   730 -SSMGKKSISHHSLPI-TSHPPLKHA-----ISQPQKRINNNGTFLRSGQGQR-TKSVSKPHREL 786

  Fly  1433 EALLKTFDQLDSSNWEVN--------------VSGLKSMVRLIRYHAETLDNQMHMTCIQLTRSV 1483
            .|:.||:..||:||..||              |.||..:..|.......:.:.:....|.:....
 Worm   787 TAVSKTYSLLDTSNMSVNQALKKMSSDEWADKVDGLNMISTLSETQPRMVADNLKEVIIAILNEC 851

  Fly  1484 RNLRSQVARASCQAAAELFSLKSTSLQQECDDLVCALLHRTAD-TNRFLRADANRALESMVDHAQ 1547
            :||||.|:|.:......:....::.:..|.:.:...||.::.| :|.|:|.||..:|..:|..|.
 Worm   852 KNLRSSVSRVAIVTIGTVAQNLNSKIDSEMEKICAVLLSKSGDVSNAFIRDDATDSLNKLVKAAT 916

  Fly  1548 PQKILNILATKGAQHQNALVRTTSAKLLFRLVERLGSDRIY-----------AMGRESRDKFFVV 1601
            ..|.|..:...||:.:|..:|::.|..::.::...||..|.           .:.:.|||:
 Worm   917 AGKALQGIILAGAKSKNNTIRSSCANFVYDIITIQGSSAILNNQNALSNVLPVLLQFSRDQ---- 977

  Fly  1602 GANLLLEGSLETRSYAKSLFRALSENHNYQRLL 1634
                    |.:.|:..|.....||::.|:.||:
 Worm   978 --------SPQVRNPGKQSLCFLSKDPNFDRLM 1002

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG42399	NP_608498.3	CLASP_N	1433..1627	CDD:289144	50/219 (23%)
che-12	NP_001256204.1	CLASP_N	<840..982	CDD:289144	33/153 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	48	1.000	Domainoid score	I8071
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004509
OrthoInspector	1	1.000	-	-		oto20496
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3085
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.030