DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gs1 and GLN1

DIOPT Version :9

Sequence 1:	NP_001162839.1	Gene:	Gs1 / 33172	FlyBaseID:	FBgn0001142	Length:	399	Species:	Drosophila melanogaster
Sequence 2:	NP_015360.2	Gene:	GLN1 / 856147	SGDID:	S000006239	Length:	370	Species:	Saccharomyces cerevisiae

Alignment Length:	359	Identity:	200/359 - (55%)
Similarity:	250/359 - (69%)	Gaps:	17/359 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    43 ALDKS-ILQRYRNLETPANRVQATYLWIDGTGENIRLKDRVLDKVPSSVEDLPDWQYDGSSTYQA 106
            :::|: |||:|..|: ...|:.|.|:|||||| |:|.|.|.|.|..:|::.||:|.:|||||.||
Yeast     5 SIEKTQILQKYLELD-QRGRIIAEYVWIDGTG-NLRSKGRTLKKRITSIDQLPEWNFDGSSTNQA 67

  Fly   107 HGENSDTTLKPRAIYRDPFKPGKNDVIVLCDTYSADGKPTASNKRAAFQAAIDLISDQEPWFGIE 171
            .|.:||..|||.|.|.|||:.|.| ::||...|:.||.|...|.|...........|:|.|||:|
Yeast    68 PGHDSDIYLKPVAYYPDPFRRGDN-IVVLAACYNNDGTPNKFNHRHEAAKLFAAHKDEEIWFGLE 131

  Fly   172 QEYTLLDVDGRPFGWPENGFPAPQGPYYCGVGADRVYARDLVEAHVVACLYAGIDFAGTNAEVMP 236
            |||||.|:....:|||:.|:|||||||||||||.:|||||::|||..||||||::.:|.||||||
Yeast   132 QEYTLFDMYDDVYGWPKGGYPAPQGPYYCGVGAGKVYARDMIEAHYRACLYAGLEISGINAEVMP 196

  Fly   237 AQWEFQIGP-AGIKACDDLWVSRYILQRIAEEYGVVVTFDPKPMEGQWNGAGAHTNFSTKEMRAD 300
            :|||||:|| .||...|.||::||.|.|:|||:|:.::|.|||::|.|||||.|||.||||||..
Yeast   197 SQWEFQVGPCTGIDMGDQLWMARYFLHRVAEEFGIKISFHPKPLKGDWNGAGCHTNVSTKEMRQP 261

  Fly   301 GGIKAIEEAIEKLSKRHERHIKAYDPKEGKDNERRLVGRLETSSIDKFSWGVANRAVSVRVPRGV 365
            ||:|.||:|||||||||..|||.|    |.||:.||.||.||:|:..||.|||||..|:|:||.|
Yeast   262 GGMKYIEQAIEKLSKRHAEHIKLY----GSDNDMRLTGRHETASMTAFSSGVANRGSSIRIPRSV 322

  Fly   366 ATAGKGYLEDRRPSSNCDPY--------AVCNAI 391
            |..|.||.|||||:||.|||        .||.||
Yeast   323 AKEGYGYFEDRRPASNIDPYLVTGIMCETVCGAI 356

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gs1	NP_001162839.1	PLN02284	54..398	CDD:177922	195/347 (56%)
Gs1	NP_001162839.1	Gln-synt_C	151..>385	CDD:278546	142/234 (61%)
GLN1	NP_015360.2	PLN02284	19..352	CDD:177922	190/339 (56%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	200	1.000	Domainoid score	I569
eggNOG	1	0.900	-	-		E1_COG0174
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37567
Inparanoid	1	1.050	433	1.000	Inparanoid score	I271
Isobase	1	0.950	-	0	Normalized mean entropy	S399
OMA	1	1.010	-	-		QHG63024
OrthoFinder	1	1.000	-	-		FOG0000848
OrthoInspector	1	1.000	-	-		otm46897
orthoMCL	1	0.900	-	-		OOG6_100668
Panther	1	1.100	-	-	O	PTHR20852
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X534
TreeFam	1	0.960	-	-
	14	13.780