Protein Alignment CG3164 and AUS1

DIOPT Version :10

• Sequence 1: NP_722605.1
• Gene: CG3164 / 33171
• FlyBaseID: FBgn0288229
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_014654.1
• Gene: AUS1 / 854175
• SGDID: S000005537
• Length: 1394
• Species: Saccharomyces cerevisiae
• Alignment Length: 750
• Identity: 172/750 - (22%)
• Similarity: 302/750 - (40%)
• Gaps: 168/750 - (22%)

  Fly     6 WKQFLENNNLLGTAGA--------GQLKAQIVPAQPKTLQHLP----------------KRPAVD 46
            |..||  |...||..:        |..|:..|.:...:|..:|                ::|..:
Yeast   680 WLPFL--NKKRGTRSSARNDSKYVGIPKSHSVSSSSSSLSAVPYQISPSNKEMALNDYNEQPITE 742

  Fly    47 --------LAFHNLTYRVKEGNRSNAKTILKGVSGRLRSGELTAIMGPSGAGKSTLLNILS-GYK 102
                    :::.|:.|.|      ..|.::...||.:.|| |||:||.|||||:||||:|| ..:
Yeast   743 TVETQKHIISWKNINYTV------GTKKLINNASGFISSG-LTALMGESGAGKTTLLNVLSQRVE 800

  Fly   103 TSSIEGSVTMNGAE-RNLSAFRKLSAYIMQDNQLHGNLTVQEAMTVATNLKLSKKFSKPEKHSMI 166
            |..:.|.:.::|.. .:..||::...::.|.: ||.:|     ::|..:|::|.........:.:
Yeast   801 TGVVSGEILIDGHPLTDEDAFKRSIGFVQQQD-LHLDL-----LSVKESLEISCLLRGDGDRAYL 859

  Fly   167 DDILLTLSLSEHRYTMTRNLSGGQKKRLSIALELVSNPP-IMFFDEPTSGLDSSTCFQCIHLLKM 230
            |.:...|.|...  .:..:|:..|:|.|||.:|||:.|. ::|.||||||||:......:..||.
Yeast   860 DTVSNLLKLPSD--ILVADLNPTQRKLLSIGVELVTKPSLLLFLDEPTSGLDAEAALTIVKFLKQ 922

  Fly   231 LAAGGRTVICTIHQPSARLFEMFDQLYTL-ADGQCVYQGSTKQLVPFL----STLNLECPSYHNP 290
            |:..|:.:.|||||||..:...||.::.| ..|:||:.|.......:.    :||..: ..:.||
Yeast   923 LSLQGQAIFCTIHQPSKSVISHFDNIFLLKRGGECVFFGPMDDACGYFMSHDNTLVYD-KEHDNP 986

  Fly   291 ASYVIEVSCGEHGDHTRKLVDAIDNGKRDVRSSADYAGLKARNDLVKVQNLKAILDKNDASSVSG 355
            |.:||               ||:.|..                                 ||...
Yeast   987 ADFVI---------------DAVGNSN---------------------------------SSAGK 1003

  Fly   356 RKYEDNLTLNNGLLNGMVNDIVKEGNVSSALV---TTNERGDAMIDVEKSVNCTTALLTEEITSP 417
            ...|:.||||...::.   ..:.|.:|...||   |.....||.   ...|:.||:|..:
Yeast  1004 DTAEEALTLNKEAIDW---SALWESSVEKKLVKKETARLEDDAR---ASGVDYTTSLWKQ----- 1057

  Fly   418 ERYPTSQFHQFWVVLKRTLLFSYRDWTLMYLRLFAHLLVGFLIGALYYDIGNDGAKVLSNLGFLF 482
                .|...|..::.:|..:.:.||.|.:..:...:...|..||..::.|.::   ::.....:|
Yeast  1058 ----PSYLQQLALITRRQYICTKRDMTYVMAKYCLNGGAGLFIGFSFWHIKHN---IIGLQDSIF 1115

  Fly   483 FNMLFLMYTSMTITIL---SFPLEMPVLLKENFNRWYSLKSYYLAISVADLPFQAIFCVIYVSIV 544
            |..:.|..:|..|..:   :...:...:.:|..:..|......|:.|:.:||.......::....
Yeast  1116 FCFMALCVSSPLINQIQDKALKTKEVYVAREARSNTYHWTVLLLSQSIIELPLALTSSTLFFVCA 1180

  Fly   545 YY---FTSQPWELFRFSMFLSACLLISFVAQSVGL-VVGAAMNVQN-GVFLAPVMSV-------- 596
            ::   |.:..|....|  ||:..|..::.: ::|| ::..|.|:|. .||:|.:.|.
Yeast  1181 FFSCGFNNAGWSAGVF--FLNYMLFAAYYS-TLGLWLIYTAPNLQTAAVFVAFIYSFTASFCGVM 1242

  Fly   597 -PFLLFSGFFVSFDAIPVYLRWI-TYLSYIRYGFE----------GTALATYGYGR---EKLRCF 646
             |:.||..|:.....:..|..:: |::|.:.:.:|          |..|.....|:   ..:..:
Yeast  1243 QPYSLFPTFWKFMYRVSPYTYFVETFVSILLHNWEIKCDMSEMVPGQPLTGQSCGQFMEAFIEEY 1307

  Fly   647 QTYCHFKSPIT-------TLEELDMVNANFTLDIV 674
            ..|.|.|:..|       |:.:..:.|.|.:.|.|
Yeast  1308 GGYLHNKNTFTVCAYCTYTVGDDFLKNENMSYDHV 1342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3164	NP_722605.1	3a01204	60..699	CDD:273361	156/663 (24%)
AUS1	NP_014654.1	3a01205	56..1369	CDD:273362	171/749 (23%)