DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3164 and ABCG39

DIOPT Version :9

Sequence 1:	NP_722605.1	Gene:	CG3164 / 33171	FlyBaseID:	FBgn0025683	Length:	699	Species:	Drosophila melanogaster
Sequence 2:	NP_176867.2	Gene:	ABCG39 / 843013	AraportID:	AT1G66950	Length:	1454	Species:	Arabidopsis thaliana

Alignment Length:	731	Identity:	181/731 - (24%)
Similarity:	324/731 - (44%)	Gaps:	152/731 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 KQFLENNNLLGTAGA----------GQLKAQIVPAQPKTLQHLPKRPAVDLAFHNLTYRVK---- 57
            ||..||.   ||.|:          |..:..::|.||           :.|||:|:.|.|.
plant   817 KQKGENR---GTEGSVVELNSSSNKGPKRGMVLPFQP-----------LSLAFNNVNYYVDMPSE 867

  Fly    58 ------EGNRSNAKTILKGVSGRLRSGELTAIMGPSGAGKSTLLNILSGYKTSS-IEGSVTMNGA 115
                  ||:|..   :|:.|.|..|.|.|||::|.|||||:||:::|:|.||.. ||||::::|.
plant   868 MKAQGVEGDRLQ---LLRDVGGAFRPGILTALVGVSGAGKTTLMDVLAGRKTGGYIEGSISISGY 929

  Fly   116 ERNLSAFRKLSAYIMQDNQLHG-NLTVQEAMTVATNLKLSKKFSKPEKHSMIDDILLTLSLSEHR 179
            .:|.:.|.::|.|..| |.:|. ::||.|::..:..|:||.......:...:::::..:.|...|
plant   930 PKNQTTFARVSGYCEQ-NDIHSPHVTVYESLIYSAWLRLSTDIDIKTRELFVEEVMELVELKPLR 993

  Fly   180 YTM-----TRNLSGGQKKRLSIALELVSNPPIMFFDEPTSGLDSSTCFQCIHLLKMLAAGGRTVI 239
            .::     ...||..|:|||:||:|||:||.|:|.||||||||:......:..::.....||||:
plant   994 NSIVGLPGVDGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDARAAAIVMRTVRNTVDTGRTVV 1058

  Fly   240 CTIHQPSARLFEMFDQLYTL-ADGQCVYQGS----TKQLVPFLSTLNLECPSY---HNPASYVIE 296
            |||||||..:||.||:|..: ..||.:|.||    :::||.:...:. ..|..   :|||:::::
plant  1059 CTIHQPSIDIFESFDELLLMKRGGQVIYAGSLGHHSQKLVEYFEAVE-GVPKINDGYNPATWMLD 1122

  Fly   297 VSCGEHGDHTRKLVDAIDNGKRDVRSSADYAGLKARNDLVKVQNLKAILDKNDASSVSGRKYEDN 361
            |:                ....:.:.|.|:|.:.:.:.|                      |..|
plant  1123 VT----------------TPSMESQMSLDFAQIFSNSSL----------------------YRRN 1149

  Fly   362 LTLNNGLLNGMVNDIVKEGNVSSALVTTNERGDAMIDVEKSVNCTTALLTEEITSPERYPTSQFH 426
                        .:::|:       ::|...|      .|.|...|.......|..:.....|:.
plant  1150 ------------QELIKD-------LSTPPPG------SKDVYFKTKYAQSFSTQTKACFWKQYW 1189

  Fly   427 QFWVVLKRTLLFSYRDWTLMYLRLFAHLLVGFLIGALYYDIG--NDGAKVLSN-LGFLFFNMLFL 488
            .:|           |......:|....:::|.|.|.:::.||  .:..:.|:| .|.::..:|||
plant  1190 SYW-----------RHPQYNAIRFLMTVVIGVLFGLIFWQIGTKTENEQDLNNFFGAMYAAVLFL 1243

  Fly   489 MYTSMTITILSFPLEMPVLLKENFNRWYSLKSYYLAISVADLPFQAIFCVIYVSIVYYFTSQPWE 553
            ...:......:..:|..|..:|.....||...|.::....::.:..|...:|..|:|......|.
plant  1244 GALNAATVQPAIAIERTVFYREKAAGMYSAIPYAISQVAVEIMYNTIQTGVYTLILYSMIGCNWT 1308

  Fly   554 LFRFSMFLSACLLISFVAQSV-GLVVGA-AMNVQ-NGVFLAPVMSVPFLLFSGFFVSFDAIPVYL 615
            :.:|..|. ..:|.||:..:: |:::.| ..|.| .|:.::..:|: :.|||||.:....||::.
plant  1309 MAKFLWFY-YYMLTSFIYFTLYGMMLMALTPNYQIAGICMSFFLSL-WNLFSGFLIPRPQIPIWW 1371

  Fly   616 RWITYLSYIRYGFEGTALATYGYGREKLRCFQTYCHFKSPITTLEELDMVNA-----NFTLDIVA 675
            ||..:.:.:.:...|...:..|   :|    .:..|    |:.:.::|:...     .|..|.:.
plant  1372 RWYYWATPVAWTLYGLITSQVG---DK----DSMVH----ISGIGDIDLKTLLKEGFGFEHDFLP 1425

  Fly   676 LIVIFVVLRISAYLFL 691
            ::.:..:..|..:||:
plant  1426 VVAVVHIAWILLFLFV 1441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3164	NP_722605.1	ABCG_EPDR	44..268	CDD:213180	91/241 (38%)
		3a01204	60..699	CDD:273361	162/658 (25%)
		ABC2_membrane	431..630	CDD:279410	44/204 (22%)
ABCG39	NP_176867.2	PLN03140	14..1454	CDD:215599	181/731 (25%)
		ABC_trans_N	94..169	CDD:291196
		P-loop_NTPase	180..430	CDD:304359
		ABC2_membrane	531..737	CDD:279410
		PDR_assoc	744..810	CDD:285559
		ABCG_PDR_domain2	850..1088	CDD:213199	92/252 (37%)
		ABC2_membrane	1183..1388	CDD:279410	47/217 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910