DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3164 and PEN3

DIOPT Version :9

Sequence 1:	NP_722605.1	Gene:	CG3164 / 33171	FlyBaseID:	FBgn0025683	Length:	699	Species:	Drosophila melanogaster
Sequence 2:	NP_176196.1	Gene:	PEN3 / 842281	AraportID:	AT1G59870	Length:	1469	Species:	Arabidopsis thaliana

Alignment Length:	709	Identity:	181/709 - (25%)
Similarity:	302/709 - (42%)	Gaps:	136/709 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 TAGAGQLKAQIVPAQPKTLQHLPKRPAVDLAFHNLTYRV-------KEGNRSNAKTILKGVSGRL 75
            :.|||..|..::|..|           :.::|.::.|.|       .:|.......:||||:|..
plant   849 SGGAGNKKGMVLPFTP-----------LAMSFDDVKYFVDMPGEMRDQGVTETRLQLLKGVTGAF 902

  Fly    76 RSGELTAIMGPSGAGKSTLLNILSGYKTSS-IEGSVTMNGAERNLSAFRKLSAYIMQDNQLHGNL 139
            |.|.|||:||.|||||:||:::|:|.||.. |||.|.::|..:....|.::|.|..|.:.....:
plant   903 RPGVLTALMGVSGAGKTTLMDVLAGRKTGGYIEGDVRISGFPKVQETFARISGYCEQTDIHSPQV 967

  Fly   140 TVQEAMTVATNLKLSKKFSKPEKHSMIDDILLTLSLSEHRYTM-----TRNLSGGQKKRLSIALE 199
            ||:|::..:..|:|.|:..|.||...:|.::..:.|...|.::     ...||..|:|||:||:|
plant   968 TVRESLIFSAFLRLPKEVGKDEKMMFVDQVMELVELDSLRDSIVGLPGVTGLSTEQRKRLTIAVE 1032

  Fly   200 LVSNPPIMFFDEPTSGLDSSTCFQCIHLLKMLAAGGRTVICTIHQPSARLFEMFDQLYTL-ADGQ 263
            ||:||.|:|.||||||||:......:..::.....||||:|||||||..:||.||:|..: ..||
plant  1033 LVANPSIIFMDEPTSGLDARAAAIVMRAVRNTVDTGRTVVCTIHQPSIDIFEAFDELMLMKRGGQ 1097

  Fly   264 CVYQG----STKQLVPFLSTLN--LECPSYHNPASYVIEVSCGEHGDHTRKLVDAIDNGKRDVRS 322
            .:|.|    ::.::|.:..:..  .:.|..:|||::::|.|                       |
plant  1098 VIYAGPLGQNSHKVVEYFESFPGVSKIPEKYNPATWMLEAS-----------------------S 1139

  Fly   323 SADYAGLKARNDLVKVQNLKAILDKNDASSVSGRKYEDNLTLNNGLLNGMVNDIVKEGNVSSALV 387
            .|  |.||...|..::.|..|:..:|.|                         :|||.:|..|
plant  1140 LA--AELKLSVDFAELYNQSALHQRNKA-------------------------LVKELSVPPA-- 1175

  Fly   388 TTNERGDAMIDVEKSVNCTTALLTEEITSPERYPTSQFHQ-FWVVLKRTLLFSYRDWTLMY---- 447
                                       .:.:.|..:||.| .|...|..|   ::.|...:
plant  1176 ---------------------------GASDLYFATQFSQNTWGQFKSCL---WKQWWTYWRSPD 1210

  Fly   448 ---LRLFAHLLVGFLIGALYYDIG---NDGAKVLSNLGFLFFNMLFLMYTSMTITILSFPLEMPV 506
               :|....|....|||.:::.||   ::...:...:|.|:..::|:...:.:.......:|..|
plant  1211 YNLVRFIFTLATSLLIGTVFWQIGGNRSNAGDLTMVIGALYAAIIFVGINNCSTVQPMVAVERTV 1275

  Fly   507 LLKENFNRWYSLKSYYLAISVADLPFQAIFCVIYVSIVYYFTSQPWELFRFSMFLSACLLISFVA 571
            ..:|.....||...|.::....:||:..|..|.|..|||......|:..:|..|:..........
plant  1276 FYRERAAGMYSAMPYAISQVTCELPYVLIQTVYYSLIVYAMVGFEWKAEKFFWFVFVSYFSFLYW 1340

  Fly   572 QSVGLV-VGAAMNVQNGVFLAPVMSVPFLLFSGFFVSFDAIPVYLRWITYLSYIRYGFEGTALAT 635
            ...|:: |....|.|.....|......|.||||||:....||.:..|..::..:.:...|..::.
plant  1341 TYYGMMTVSLTPNQQVASIFASAFYGIFNLFSGFFIPRPKIPKWWIWYYWICPVAWTVYGLIVSQ 1405

  Fly   636 YGYGREKLRCFQTYCHFKSPITTLEELDMVNANFTLD----IVALIVIFVVLRISAYLF 690
            ||....:::...     .:|..|:::....:..|..|    :.|:::.|.|  ..|::|
plant  1406 YGDVETRIQVLG-----GAPDLTVKQYIEDHYGFQSDFMGPVAAVLIAFTV--FFAFIF 1457

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3164	NP_722605.1	ABCG_EPDR	44..268	CDD:213180	90/237 (38%)
		3a01204	60..699	CDD:273361	171/660 (26%)
		ABC2_membrane	431..630	CDD:279410	45/209 (22%)
PEN3	NP_176196.1	PLN03140	31..1469	CDD:215599	181/709 (26%)
		ABC_trans_N	89..165	CDD:291196
		ABCG_PDR_domain1	154..426	CDD:213200
		ABC2_membrane	527..733	CDD:279410
		PDR_assoc	740..800	CDD:285559
		ABCG_PDR_domain2	864..1102	CDD:213199	91/248 (37%)
		ABC2_membrane	1197..1404	CDD:279410	45/209 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910