DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3164 and ABCG26

DIOPT Version :9

Sequence 1:	NP_722605.1	Gene:	CG3164 / 33171	FlyBaseID:	FBgn0025683	Length:	699	Species:	Drosophila melanogaster
Sequence 2:	NP_187928.2	Gene:	ABCG26 / 820512	AraportID:	AT3G13220	Length:	685	Species:	Arabidopsis thaliana

Alignment Length:	733	Identity:	200/733 - (27%)
Similarity:	343/733 - (46%)	Gaps:	129/733 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 NQYSWKQFLENNNLLGTAGAGQLKAQIVPAQPKTLQHLPKRPAVDLAFHNLTYRVKEGNRSNA-- 64
            ||||.:..::.              :.|...|.....||    :.|.|.::.|:|:..:.|:|
plant    38 NQYSSEIDIDE--------------EFVSTYPLEDAPLP----IFLKFEDVEYKVRNSHASSANL 84

  Fly    65 -------------------KTILKGVSGRLRSGELTAIMGPSGAGKSTLLNILSGYKTSSIEGSV 110
                               |.||||::|....||:.|:|||||:||:|||.|:.|..|.:::|.:
plant    85 VKTMVSKVVTHTNPDPDGYKHILKGITGSTGPGEILALMGPSGSGKTTLLKIMGGRLTDNVKGKL 149

  Fly   111 TMNGAERNLSAFRKLSAYIMQDNQLHGNLTVQEAMTVATNLKLSKKFSKPEKHSMIDDILLTLSL 175
            |.|....:.|..|:: .::.||:.|...|||:|.:..|..|:|....||.:|::.|:.|:..|.|
plant   150 TYNDIPYSPSVKRRI-GFVTQDDVLLPQLTVEETLAFAAFLRLPSSMSKEQKYAKIEMIIKELGL 213

  Fly   176 SEHRYT-----MTRNLSGGQKKRLSIALELVSNPPIMFFDEPTSGLDSSTCFQCIHLLKMLAAGG 235
            ...|.|     ..:.:|||::||.|||.|::.:|.::..|||||||||::..:.:|:|:.:|..|
plant   214 ERCRRTRVGGGFVKGISGGERKRASIAYEILVDPSLLLLDEPTSGLDSTSATKLLHILQGVAKAG 278

  Fly   236 RTVICTIHQPSARLFEMFDQLYTLADGQCVYQGSTKQLVPFLSTLNLECPSYHNPASYVIEVSCG 300
            ||||.||||||:|:|.|||:|..:::|...:.|..::.:.:.|:|.:......|||.::::::.|
plant   279 RTVITTIHQPSSRMFHMFDKLLLISEGHPAFYGKARESMEYFSSLRILPEIAMNPAEFLLDLATG 343

  Fly   301 EHGDHTRKLVDAIDNGKRDVRSSADYAGLKARNDLVKV------QNLKAILD-KNDASSVSGRKY 358
            :..|.:  |.|.:            .|...|:.|..:|      |..|..|: |....:...||.
plant   344 QVSDIS--LPDEL------------LAAKTAQPDSEEVLLKYLKQRYKTDLEPKEKEENHRNRKA 394

  Fly   359 EDNLTLNNGLLNGMVNDIVKEGNVSSALVTTNERGDAMIDVEKSVNCTTALLTEEITSPERYPTS 423
            .::|.:                               .|.|:|.                 :..|
plant   395 PEHLQI-------------------------------AIQVKKD-----------------WTLS 411

  Fly   424 QFHQFWVVLKRTLLFSYRDWTLMYLRLFAHLLVGFLIGALYYDIGND-GAKVLSNLGFLFFNMLF 487
            .:.||.::.:||.....||: ...|||...|.|..::|.|::....| .|.:...:|.:|:..:|
plant   412 WWDQFLILSRRTFRERRRDY-FDKLRLVQSLGVAVVLGLLWWKSKTDTEAHLRDQVGLMFYICIF 475

  Fly   488 LMYTSMTITILSFPLEMPVLLKENFNRWYSLKSYYLAISVADLPFQAIFCVIYVSIVYYFTSQPW 552
            ...:|:...:..||.|...|:||.....|.|..||:..::.|:....::...::.|||:......
plant   476 WTSSSLFGAVYVFPFEKIYLVKERKAEMYRLSVYYVCSTLCDMVAHVLYPTFFMIIVYFMAEFNR 540

  Fly   553 ELFRFSMFLSACLLISFVAQSVGLVVGAA-MNVQNGVFLAPVMSVPFLLFSGFFVSFDAIPVYLR 616
            .:..|...:...|||:..:|..|..:||: ::::....:|.::.:.|||..|::|..  ||.:::
plant   541 NIPCFLFTVLTILLIAITSQGAGEFLGASVLSIKRAGMIASLVLMLFLLTGGYYVQH--IPKFMQ 603

  Fly   617 WITYLSYIRYGFEGTALATYGYGREKLRCFQTYCHFKSPITTLE---ELDMVNANFTL-DIVALI 677
            |:.|||::.|||.  .|....|..::|  |:  |..|....||:   ..|.:|.|..| ::..|:
plant   604 WLKYLSFMHYGFR--LLLKVQYSADQL--FE--CGSKGGCRTLQSSSSFDTINLNGGLQELWVLL 662

  Fly   678 VIFVVLRISAYLFLRWKL 695
            .:....|:.||..||.|:
plant   663 AMAFGYRLCAYFCLRKKI 680

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3164	NP_722605.1	ABCG_EPDR	44..268	CDD:213180	92/249 (37%)
		3a01204	60..699	CDD:273361	188/675 (28%)
		ABC2_membrane	431..630	CDD:279410	54/200 (27%)
ABCG26	NP_187928.2	PLN03211	62..678	CDD:215634	191/691 (28%)
		ABCG_EPDR	93..311	CDD:213180	86/218 (39%)
		ABC2_membrane	435..621	CDD:279410	51/189 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	85	1.000	Domainoid score	I2816
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.720