DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3164 and CG9663

DIOPT Version :9

Sequence 1:	NP_722605.1	Gene:	CG3164 / 33171	FlyBaseID:	FBgn0025683	Length:	699	Species:	Drosophila melanogaster
Sequence 2:	NP_608760.2	Gene:	CG9663 / 33541	FlyBaseID:	FBgn0031516	Length:	808	Species:	Drosophila melanogaster

Alignment Length:	709	Identity:	287/709 - (40%)
Similarity:	416/709 - (58%)	Gaps:	40/709 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 ENNNLLGTAGAGQLKAQIVP-AQPKTLQHLPKRPAVDLAFHNLTYRVKEG-NRSNAKTILKGVSG 73
            |:.|...||.:|   ..|.| .|.||::      .:::.|.|:.|..|.| .:...|.:|.|::|
  Fly   120 ESRNTSSTATSG---GSIFPHEQYKTIK------KINIGFENIRYTTKFGVFQRETKDVLMGLTG 175

  Fly    74 RLRSGELTAIMGPSGAGKSTLLNILSGYKTSSIEGSVTMNGAERNLSAFRKLSAYIMQDNQLHGN 138
            ..:||||:|::|||||||||||||||||.|....|...:||..|:|.||:...|:|.||..|...
  Fly   176 YFKSGELSAVIGPSGAGKSTLLNILSGYTTYGFTGDFRVNGNRRDLKAFKSNVAFIRQDTSLQAF 240

  Fly   139 LTVQEAMTVATNLKLSKKFSKPEKHSMIDDILLTLSLSEHRYTMTRNLSGGQKKRLSIALELVSN 203
            |:|:|||..|.|||:....:..||...:..||..:.:.|:|:|.|..|||||||||:||||||:|
  Fly   241 LSVKEAMHFAANLKIGTHMTHSEKRERVKCILEAIGMYENRHTRTGQLSGGQKKRLAIALELVNN 305

  Fly   204 PPIMFFDEPTSGLDSSTCFQCIHLLKMLAAGGRTVICTIHQPSARLFEMFDQLYTLADGQCVYQG 268
            ||::..||||:||||.|..|.|:|||.||..|||||||||||||..|.|||.||.:.:|:|:|.|
  Fly   306 PPVLILDEPTTGLDSFTSNQLINLLKKLAIEGRTVICTIHQPSALTFAMFDHLYAIGEGKCIYAG 370

  Fly   269 STKQLVPFLSTLNLECPSYHNPASYVIEVSCGEH----GDHTRKLVDAIDNGK-RDVRSS----- 323
            ..:.|:|||..|||.||..:|||.|::|::..::    .:...|||..:|||: .|.|.|
  Fly   371 GAQNLLPFLGALNLHCPESYNPADYLMEIATHDYDTAEDNQLEKLVALMDNGRNEDYRQSKTARV 435

  Fly   324 ADYAGLKARNDLVKVQNLKAILDKNDASSV-----SGRKYEDNLTLNNGLLNGMVND--IVKEGN 381
            |..|.:|..:.|:....:..:.....::||     .|..::....:|.  |:..|.|  ....||
  Fly   436 AQLAAMKKVDQLMAAGLITPVTAPVMSTSVPAHFMQGNTFKPLTPINE--LSSRVWDSQTAGIGN 498

  Fly   382 VSSALVTTNE-RGDAMIDVEKSVNCTTALLTEEITSPERYPTSQFHQFWVVLKRTLLFSYRDWTL 445
            ..|......: :....|:::.|..|....:         |.|..:.|..::|.||.|..:||.:|
  Fly   499 AGSCCKPKKKNKSRPAIELDPSHLCKRQNI---------YATPFYRQLSILLVRTFLLIWRDSSL 554

  Fly   446 MYLRLFAHLLVGFLIGALYYDIGNDGAKVLSNLGFLFFNMLFLMYTSMTITILSFPLEMPVLLKE 510
            ..:|...||:.|.|||.||:.||||.|:.|:...:||:.::|:||.:.:..::.||||.|::.:|
  Fly   555 TTMRFAIHLITGILIGTLYFGIGNDAAQTLNIFRYLFYTIMFIMYCAFSGILVKFPLEFPIVSRE 619

  Fly   511 NFNRWYSLKSYYLAISVADLPFQAIFCVIYVSIVYYFTSQPWELFRFSMFLSACLLISFVAQSVG 575
            :|||||||::||:||::||||.|.|...:::...|..|.||.||:||.||.....:.:.|:||:|
  Fly   620 HFNRWYSLRAYYVAITLADLPIQIICSALFIVPTYLMTQQPLELWRFGMFFLIVFVTALVSQSIG 684

  Fly   576 LVVGAAMNVQNGVFLAPVMSVPFLLFSGFFVSFDAIPVYLRWITYLSYIRYGFEGTALATYGYGR 640
            |.||||::::.|..|.|....|||.|||||:.....||:|||:..:|:::|..||..:|.:||.|
  Fly   685 LAVGAALSLKLGSILGPFFICPFLQFSGFFLMEKDAPVFLRWMFDISFLKYSLEGATMAIFGYDR 749

  Fly   641 EKLRCFQTYCHFKSPITTLEELDMVNANFTLDIVALIVIFVVLRISAYLFLRWKLKTVR 699
            |.|.|.:.|||.:.|...|:.|||.|.|:||.::.|..:.|.|||.|:..:.::|:..|
  Fly   750 EPLACNELYCHLRHPQFILKSLDMANGNYTLALIFLFGVLVFLRILAFYIMSFRLRLFR 808

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3164	NP_722605.1	ABCG_EPDR	44..268	CDD:213180	117/224 (52%)
		3a01204	60..699	CDD:273361	271/656 (41%)
		ABC2_membrane	431..630	CDD:279410	87/198 (44%)
CG9663	NP_608760.2	ABCG_EPDR	145..370	CDD:213180	117/224 (52%)
		3a01204	149..808	CDD:273361	276/669 (41%)
		ABC2_membrane	540..743	CDD:279410	89/202 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	121	1.000	Domainoid score	I1855
eggNOG	1	0.900	-	-		E2759_KOG0061
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28143
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	1	1.000	-	-		mtm14984
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	1	1.100	-	-	P	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
	10	9.830