DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3164 and Abcg3l1

DIOPT Version :9

Sequence 1:	NP_722605.1	Gene:	CG3164 / 33171	FlyBaseID:	FBgn0025683	Length:	699	Species:	Drosophila melanogaster
Sequence 2:	NP_001004076.2	Gene:	Abcg3l1 / 289453	RGDID:	1303294	Length:	646	Species:	Rattus norvegicus

Alignment Length:	684	Identity:	167/684 - (24%)
Similarity:	306/684 - (44%)	Gaps:	95/684 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 AQPKTLQHLPKRPAVDLAFHNLTYR--VKEG----NRSNAKTILKGVSGRLRSGELTAIMGPSGA 89
            :.|:||    .:.|| |:|||::||  |:.|    .::.....|..:||.:..| |.|||||...
  Rat    26 SDPETL----TKEAV-LSFHNISYRETVQSGFPLRQQTRVMERLSSISGIMGPG-LNAIMGPQDG 84

  Fly    90 GKSTLLNILSGYK-TSSIEGSVTMNGAERNLSAFRKLSAYIMQDNQLHGNLTVQEAMTVATNLKL 153
            .:|.||::|:..: ...:.|.:.:||..|..: |:..|.||.|::.:.|.:||::.:..:..|:|
  Rat    85 SRSLLLDVLAARRDPCGLSGDILINGKPRPAN-FKCTSGYIPQNDVVLGTVTVRDNLEFSAALRL 148

  Fly   154 SKKFSKPEKHSMIDDILLTLSLSEHRYTMTRNLSGGQKKRLSIALELVSNPPIMFFDEPTSGLDS 218
            ....::.||...|:::|..|.|.:.:....|  |.|.:||.|||:|||:..||:|.|:||:|||.
  Rat   149 PMTVTRDEKRRRINEVLELLHLEKEQNVKPR--SKGLRKRTSIAMELVTEHPILFLDDPTTGLDL 211

  Fly   219 STCFQCIHLLKMLAAGGRTVICTIHQPSARLFEMFDQLYTLADGQCVYQGSTKQLVPFLSTLNLE 283
            .|....|.:|:.::..|:|:|.:|:||...:|..||.|..:|.|:.::.|..:..:.:.::...:
  Rat   212 RTTTDVISILRRMSMKGKTIIFSINQPQYSIFRFFDSLTLVASGKLMFHGPARDALEYFTSAGYQ 276

  Fly   284 CPSYHNPASYVIEVSCGEHGDHTRKLVDAIDNGKRDVRSSADYAGLKARNDLVKVQNLKAILDKN 348
            ..|::|||.:               .:|.|:.|..|.......|                  |:|
  Rat   277 YESHNNPADF---------------FLDVINGGFPDTEEDGHEA------------------DEN 308

  Fly   349 DASSVSGRKYEDNLTLNNGLLNGMVNDIVKEGNVSSALVTTNERGDAMIDVEKSVNCTTALLTEE 413
            :  ....|:::         :.|.:.::..:..:.||   |..|.|.::. |:.::.::|:.|..
  Rat   309 E--EFVERQHQ---------VTGKLANMYAQSPLHSA---TRARLDQLLG-EQKLDRSSAVETTC 358

  Fly   414 ITSPERYPTSQFHQF-WVVLKRTLLFSYRDWTLMYLRLFAHLLVGFLIGALYYDIGNDGAKVLSN 477
            :       |..:||. |:..:....|....| :..:::...:::..::|..:..:.|...::...
  Rat   359 V-------TPFWHQLGWITRRSFKNFLGFPW-VTTIQVIIIVILAVVVGTAFRLLQNVCTELQMR 415

  Fly   478 LGFLFFNMLFLMYTSMTITILSFPLEMPVLLKENFNRWYSLKSYYLAISVADL-PFQAIFCVIYV 541
            ...:.....|...||:|...| |.::....|.|:.:.:|.:.||:....:|:| |.:.:...|:.
  Rat   416 AILILLLTGFQCITSVTAGEL-FVIDQDRFLHEHTSGYYRVSSYFFGKLLAELIPRRLLPSTIFT 479

  Fly   542 SIVYYFTSQPWELFRFSMFLSACLLISFVAQSVGLVVGAAMNVQN-GVFLAPVMSVPFLLFSGFF 605
            .|.|:.......:..|.......:::::.|.|:.|.:||..||.. ...|..:..|..|.|||..
  Rat   480 LITYFIAGLRTSVRGFFTMTFTIMMLAYSASSLSLSLGAGENVAAITTLLVTIYFVFMLFFSGLS 544

  Fly   606 VSFDAIPVYLRWITYLSYIRYGFEGTALATY-------GYGREKLRCFQTYCHFKSPITTLEE-- 661
            :....:|| |.||.|.|...|||.......:       .|..|::...|.|.     |.|.||
  Rat   545 LDTGFLPV-LSWIRYFSIPHYGFRALLHNEFLGQNFCPEYNTEEVSRCQNYV-----ICTGEEFL 603

  Fly   662 ----LDMVNANFTLDIVALIVIFVVLRISAYLFL 691
                ..:.:..|..:.:||....::|....|:.|
  Rat   604 EIQGFHLSSWGFWENHLALACTMIILLTITYVQL 637

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3164	NP_722605.1	ABCG_EPDR	44..268	CDD:213180	79/230 (34%)
		3a01204	60..699	CDD:273361	154/649 (24%)
		ABC2_membrane	431..630	CDD:279410	45/200 (23%)
Abcg3l1	NP_001004076.2	P-loop_NTPase	35..261	CDD:304359	79/230 (34%)
		3a01204	64..644	CDD:273361	154/641 (24%)
		ABC2_membrane	369..572	CDD:279410	45/205 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.720