Protein Alignment CG3164 and Abcg4

DIOPT Version :9

• Sequence 1: NP_722605.1
• Gene: CG3164 / 33171
• FlyBaseID: FBgn0025683
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_620405.3
• Gene: Abcg4 / 192663
• MGIID: 1890594
• Length: 646
• Species: Mus musculus
• Alignment Length: 681
• Identity: 307/681 - (45%)
• Similarity: 414/681 - (60%)
• Gaps: 77/681 - (11%)

  Fly    23 QLKAQIVPAQPKTLQHLPKRPAVDLAFHNLTYRVKEG---NRSNAKTILKGVSGRLRSGELTAIM 84
            :::..|..||  ...|||||.|||:.|..|:|.|:||   .:...||:||.:||:....||..||
Mouse    39 KVENHITEAQ--RFSHLPKRSAVDIEFVELSYSVREGPCWRKRGYKTLLKCLSGKFCRRELIGIM 101

  Fly    85 GPSGAGKSTLLNILSGYKTSSIEGSVTMNGAERNLSAFRKLSAYIMQDNQLHGNLTVQEAMTVAT 149
            |||||||||.:|||:||:.|.::|.:.:||..|.|..|||:|.|||||:.|..:|||.|||.|:.
Mouse   102 GPSGAGKSTFMNILAGYRESGMKGQILVNGRPRELRTFRKMSCYIMQDDMLLPHLTVLEAMMVSA 166

  Fly   150 NLKLSKKFSKPEKHSMIDDILLTLSLSEHRYTMTRNLSGGQKKRLSIALELVSNPPIMFFDEPTS 214
            |||||:|  :..|..::.:||..|.|....:|.|..|||||:|||:||||||:|||:||||||||
Mouse   167 NLKLSEK--QEVKKELVTEILTALGLMSCSHTRTALLSGGQRKRLAIALELVNNPPVMFFDEPTS 229

  Fly   215 GLDSSTCFQCIHLLKMLAAGGRTVICTIHQPSARLFEMFDQLYTLADGQCVYQGSTKQLVPFLST 279
            ||||::|||.:.|:|.||.||||||||||||||:||||||:||.|:.|||:::|....|:|:|..
Mouse   230 GLDSASCFQVVSLMKSLAHGGRTVICTIHQPSAKLFEMFDKLYILSQGQCIFKGVVTNLIPYLKG 294

  Fly   280 LNLECPSYHNPASYVIEVSCGEHGDHTRKLVDAIDNGKRDVRSSADYAGLKARNDLVKVQNLKAI 344
            |.|.||:|||||.::|||:.||:||....|..|:.||                  |..:...|:.
Mouse   295 LGLHCPTYHNPADFIIEVASGEYGDLNPMLFRAVQNG------------------LCTMAEKKSS 341

  Fly   345 LDKNDASSVSGRKYEDNLTLNNGLLNGMVNDIVKEGNVSSALVTTNERGDAMIDVEKSVNCTTAL 409
            ..||                                                   |...:|.|..
Mouse   342 PGKN---------------------------------------------------ELPAHCPTCP 355

  Fly   410 LTEEITSPERYPTSQFHQFWVVLKRTLLFSYRDWTLMYLRLFAHLLVGFLIGALYYDIGNDGAKV 474
            ...:......:.||...||.::.:||.|...||..|.:||..:|:|:|.|||.||..||:|.:||
Mouse   356 PELDPIESHTFATSTLTQFCILFRRTFLSILRDTVLTHLRFMSHVLIGVLIGLLYLHIGDDASKV 420

  Fly   475 LSNLGFLFFNMLFLMYTSMTITILSFPLEMPVLLKENFNRWYSLKSYYLAISVADLPFQAIFCVI 539
            .:|.|||||:|||||:.::..|:|:|||||.|.::|:.|.||:||:||||.::||:|||.:..|:
Mouse   421 FNNTGFLFFSMLFLMFAALMPTVLTFPLEMAVFMREHLNYWYTLKAYYLAKTMADVPFQVVCPVV 485

  Fly   540 YVSIVYYFTSQPWELFRFSMFLSACLLISFVAQSVGLVVGAA-MNVQNGVFLAPVMSVPFLLFSG 603
            |.||||:.|.||.|..||.:|.:..:..:.||||:||::||| .::|...|:.||.::|.|||||
Mouse   486 YCSIVYWMTGQPAETSRFLLFSALAIATALVAQSLGLLIGAASTSLQVATFVGPVTAIPVLLFSG 550

  Fly   604 FFVSFDAIPVYLRWITYLSYIRYGFEGTALATYGYGREKLRCFQTYCHFKSPITTLEELDMVNAN 668
            |||||..||.||:|.:||||:||||||..|..||..|..|.|....|.|:.|...|.|||:..|.
Mouse   551 FFVSFKTIPTYLQWSSYLSYVRYGFEGLILTIYGMERGHLTCLDEQCPFRDPQIILRELDVEEAK 615

  Fly   669 FTLDIVALIVIFVVLRISAYLFLRWKLKTVR 699
            ..:|.:.|.:.|:.||:.|||.||:::|:.|
Mouse   616 LYMDFLVLGIFFLALRLLAYLVLRYRVKSER 646

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3164	NP_722605.1	ABCG_EPDR	44..268	CDD:213180	131/226 (58%)
		3a01204	60..699	CDD:273361	289/639 (45%)
		ABC2_membrane	431..630	CDD:279410	105/199 (53%)
Abcg4	NP_620405.3	3a01204	44..646	CDD:273361	306/674 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	144	1.000	Domainoid score	I4581
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100076
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R138
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.800