Protein Alignment CG3164 and wht-2

DIOPT Version :10

• Sequence 1: NP_722605.1
• Gene: CG3164 / 33171
• FlyBaseID: FBgn0288229
• Length: 699
• Species: Drosophila melanogaster
• Sequence 2: NP_502164.1
• Gene: wht-2 / 178069
• WormBaseID: WBGene00007513
• Length: 610
• Species: Caenorhabditis elegans
• Alignment Length: 690
• Identity: 205/690 - (29%)
• Similarity: 320/690 - (46%)
• Gaps: 162/690 - (23%)

  Fly    45 VDLAFHNLTYRVKEGNRSNAKTILKGVSGRLRSGELTAIMGPSGAGKSTLLNI-----LSGYKTS 104
            |.|.:||::...::    :.|.||:.|||..:.|:|.|:||.|||||:||||:     |.|.:||
 Worm    32 VTLTWHNISIHAEK----SGKQILENVSGIAKPGQLLALMGASGAGKTTLLNMLLSRNLRGLETS 92

  Fly   105 SIEGSVTMNGAE--RNLSAFRKLSAYIMQDNQLHGNLTVQEAMTVATNLKLSKKFSKPEKHSMID 167
               |||.:||.|  |.::|   :|.|..||....|.|||:|.:.:...|:::....|  :...:.
 Worm    93 ---GSVKVNGHELGRGITA---ISGYAQQDELFVGTLTVKEYLDIQAKLRVNGDSEK--RRRRVG 149

  Fly   168 DILLTLSLSEHRYTM------TRNLSGGQKKRLSIALELVSNPPIMFFDEPTSGLDSSTCFQCIH 226
            :::..|.|.:.:.|.      .:.:|||:.:||:.|.||:|||.|:|.||||:||||......:.
 Worm   150 NVMSQLGLYKCQNTRIGTIGGQKGISGGEMRRLTFACELLSNPSILFCDEPTTGLDSFMAESVVQ 214

  Fly   227 LLKMLAAGGRTVICTIHQPSARLFEMFDQLYTLADGQCVYQGSTKQLVPFLSTLNLECPSYHNPA 291
            :|..||..||||||||||||::|:.|||::..:|.|:..:.||.:..:.|.......||...|||
 Worm   215 VLSNLAKSGRTVICTIHQPSSQLYLMFDRVMFMAGGKTAFLGSPRDAIQFFEDAGFACPRNFNPA 279

  Fly   292 SYVIEVSCGEHGDHTRKLVDAIDNGKRDVRSSADYAGLKARNDLVKVQNLKAILDKNDASSVSGR 356
            ..:|         ||.    |:...:.|          |.|      |.::.|..|...||. ||
 Worm   280 DLII---------HTL----AVMPNEED----------KCR------QRIEVIYTKFQNSSY-GR 314

  Fly   357 KYEDNLTLNNGLLNGMVNDIVKEGNVSSALVTTNERGDAMIDVEKSVNCTTALLTEEITSP-ERY 420
                  ||..|                               ||||         :|...| ||:
 Worm   315 ------TLKFG-------------------------------VEKS---------DEGQRPSERH 333

  Fly   421 PTSQFHQFWVVLKRTLLFSYRDWTLMYLRLFAHLLVGFLIGALYY-----DIGNDGAKVLSNL-G 479
            .|....|...:|:|:.:.::|:.:|...::....::|..||.||.     .||      :||| |
 Worm   334 KTGILTQIGALLERSAIDTWRNPSLTRAKVIQKSIMGLFIGLLYLQSPLTSIG------ISNLNG 392

  Fly   480 FLFFNMLFLMYTSMTITILSF-PLEMPVLLKENFNRWYSLKSYYLAISVADLPFQAIFCVIYVSI 543
            .||:.:..|.|::: ..||:| |.:.|::.:|..:..||:.|||:|..::.||......:|.:.:
 Worm   393 ALFYLVCELTYSTI-FGILNFLPADFPLVSREYHDGLYSVFSYYVARCLSYLPLFTADGLIMLLV 456

  Fly   544 VYY---FTSQPWELFRFSMFLSACLLISFVAQS---VGLVVGAAMNVQNGVFLAPVMSVPFL--- 599
            .|:   |:|.      .:..|.|||:...:.||   .|:::..   :...:.:|...:.|.|
 Worm   457 SYWMVGFSSS------ITQVLYACLIAFLIEQSSSACGIMISC---ISPSLPIAMSTAGPMLTLL 512

  Fly   600 -LFSGFFVSFDAIPVYLRWITYLSYIRYGFEGTALATYGYGREKLRCFQTYCHFKSPITTLEELD 663
             |..|.:.:..|:|.|:.||.|||:.|||||..|:..:....|:          .:.|.|.|:.|
 Worm   513 SLTGGLYANVGALPSYISWIQYLSWFRYGFEAFAINQWSSVNEQ----------NTTIWTDEKRD 567

  Fly   664 MVNAN-------FTLDIV---ALIVIF-------VVLRIS 686
            .|.:.       |..|:.   |.|:||       :.||:|
 Worm   568 SVLSQLSFRAEMFYPDLFIMSAFILIFYTIGYAGLALRVS 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3164	NP_722605.1	3a01204	60..699	CDD:273361	201/675 (30%)
wht-2	NP_502164.1	3a01204	44..610	CDD:273361	201/678 (30%)