Protein Alignment CG4822 and PDR12

DIOPT Version :10

• Sequence 1: NP_608493.2
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_015267.1
• Gene: PDR12 / 856049
• SGDID: S000005979
• Length: 1511
• Species: Saccharomyces cerevisiae
• Alignment Length: 720
• Identity: 176/720 - (24%)
• Similarity: 311/720 - (43%)
• Gaps: 153/720 - (21%)

  Fly    25 NADSLEPDQSE----------DFQTVLGLKYLPSWPAVNLQFSELCYVVPDQTNASKTKTILRRV 79
            |||:....:.|          |.:.|:..|.:.:|       :.|.|.:|..   ..|:.:|..|
Yeast   810 NADARTASREEMMEALNGPNVDLEKVIAEKDVFTW-------NHLDYTIPYD---GATRKLLSDV 864

  Fly    80 NGMFHSHELTAIIGPSGAGKTTLLNLLA---GFGAVCESGEILVNNSPRDMRVFRKMSRYIMQTD 141
            .|.....::||::|.||||||||||:||   ..|.:  :|::|||..|.... |.:...|:.|.|
Yeast   865 FGYVKPGKMTALMGESGAGKTTLLNVLAQRINMGVI--TGDMLVNAKPLPAS-FNRSCGYVAQAD 926

  Fly   142 VLDSQFTVLEMMILAANLKLGKELNLKQKLEVIDEILGMLRLKDTLNTMAQKLSGG----ERKRL 202
            ...::.:|.|.:..||.|:....:.|::|.|.:::|:.:|.:::....:..|...|    :||:|
Yeast   927 NHMAELSVRESLRFAAELRQQSSVPLEEKYEYVEKIITLLGMQNYAEALVGKTGRGLNVEQRKKL 991

  Fly   203 CIALELVNNPP-VIFLDEPTTGLDDLSSSQCIALLKVLAAGGRTVICSIHTPSAKIFEMLDAVYV 266
            .|.:|||..|. ::||||||:|||..|:...:..::.||..|::::|:||.|||.:||..|.:.:
Yeast   992 SIGVELVAKPSLLLFLDEPTSGLDSQSAWSIVQFMRALADSGQSILCTIHQPSATLFEQFDRLLL 1056

  Fly   267 LAE-GQCVYQGK-GSNIVPFLKNF----GLCCPITYNPADFIIEVACLEYGGS------YHEPMV 319
            |.: |:.||.|. |.|....||.|    |:.|.::.|||::|:.  |:..|.:      :|:
Yeast  1057 LKKGGKMVYFGDIGPNSETLLKYFERQSGMKCGVSENPAEYILN--CIGAGATASVNSDWHD--- 1116

  Fly   320 EAVGNGKVARW--SPPAVEGETTTTKTDTTSGASSFYERDQFDEEISPKLLEAKCSWWLQYKLLL 382
                     .|  ||..........:...|....:..:    |.|::.:.   ..|:..|.|.:|
Yeast  1117 ---------LWLASPECAAARAEVEELHRTLPGRAVND----DPELATRF---AASYMTQIKCVL 1165

  Fly   383 VRMLIQMWRDKSYIKLKFYMNIVLALLVGSLYFGMGTSASKALFNFGFMF-TIVIAYLYLPMMPV 446
            .|..:|.||...||:.||:..:..||.||..|.|:..|...|:..|..:| .::||...:..:.|
Yeast  1166 RRTALQFWRSPVYIRAKFFECVACALFVGLSYVGVNHSVGGAIEAFSSIFMLLLIALAMINQLHV 1230

  Fly   447 LLYFPTEINLLKREYNN--QWYRLSSYYAAMVT--SKLPSMFILAVIYLSIVY--LMSSQPLEWF 505
            ..|...|:..::...:|  .|..|...:||:..  |.|.........|....:  ..|.....:|
Yeast  1231 FAYDSRELYEVREAASNTFHWSVLLLCHAAVENFWSTLCQFMCFICYYWPAQFSGRASHAGFFFF 1295

  Fly   506 RFAMLFTIAFVTALTSDSFGL-------------LISSRLSLVNAMFMG---PVLAVPL----IL 550
            .:.::|.:.|||      :||             :|:|.|.....:|.|   |...:|.    ::
Yeast  1296 FYVLIFPLYFVT------YGLWILYMSPDVPSASMINSNLFAAMLLFCGILQPREKMPAFWRRLM 1354

  Fly   551 LSIYGIGYGGGTYISPLMRFLMHLSYLRHSMEGLVASLYDYGRAD-------------------- 595
            .::....|.....::||:          |:.: :|.:.::|...|
Yeast  1355 YNVSPFTYVVQALVTPLV----------HNKK-VVCNPHEYNIMDPPSGKTCGEFLSTYMDNNTG 1408

  Fly   596 -----TICEDTEIFCSFKKSKVLLAFLG------FENMHYLWSLSCLMSFYLLFTVAA----YFM 645
                 |..|:.: :|.:.....::|...      :.|..::|:       |:.|.:||    |::
Yeast  1409 YLVNPTATENCQ-YCPYTVQDQVVAKYNVKWDHRWRNFGFMWA-------YICFNIAAMLICYYV 1465

  Fly   646 IRLRL 650
            :|:::
Yeast  1466 VRVKV 1470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_608493.2	3a01204	67..654	CDD:273361	165/668 (25%)
PDR12	NP_015267.1	3a01205	89..1468	CDD:273362	175/716 (24%)