Protein Alignment CG4822 and ADP1

DIOPT Version :10

• Sequence 1: NP_608493.2
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_009937.2
• Gene: ADP1 / 850369
• SGDID: S000000604
• Length: 1049
• Species: Saccharomyces cerevisiae
• Alignment Length: 705
• Identity: 176/705 - (24%)
• Similarity: 305/705 - (43%)
• Gaps: 129/705 - (18%)

  Fly    46 LPSWPAVN------------LQFSELCYVVPDQTNASKTKTILRRVNGMFHSHELTAIIGPSGAG 98
            ||...|||            |.|..:.|.||...:....:|:|..::|:....::.||:|.||||
Yeast   364 LPDEDAVNNFLQNEDDTLATLSFENITYSVPSINSDGVEETVLNEISGIVKPGQILAIMGGSGAG 428

  Fly    99 KTTLLNLLA---GFGAVCESGEILVNNSPRDMRVFRKMSRYIMQTDVLDSQFTVLEMMILAANLK 160
            |||||::||   ..|.|  ||.|.||....|.:.|.|:..::.|.|.|....||.|.::.:|.|:
Yeast   429 KTTLLDILAMKRKTGHV--SGSIKVNGISMDRKSFSKIIGFVDQDDFLLPTLTVFETVLNSALLR 491

  Fly   161 LGKELNLKQKLEVIDEILGMLR---LKDTL--NTMAQKLSGGERKRLCIALELVNNPPVIFLDEP 220
            |.|.|:.:.|...:.::|..||   :||.:  |...:.:||||::|:.||.|||.:|.|:|||||
Yeast   492 LPKALSFEAKKARVYKVLEELRIIDIKDRIIGNEFDRGISGGEKRRVSIACELVTSPLVLFLDEP 556

  Fly   221 TTGLDDLSSSQCI-ALLKVLAAGGRTVICSIHTPSAKIFEMLDAVYVLAEGQCVYQGKGSNIVPF 284
            |:|||..:::..| .|:::.:...||::.|||.|.:.||.:.|.:.:|::|:.||.|....:..|
Yeast   557 TSGLDASNANNVIECLVRLSSDYNRTLVLSIHQPRSNIFYLFDKLVLLSKGEMVYSGNAKKVSEF 621

  Fly   285 LKNFGLCCPITYNPADFIIE----------------VACLEYG-------GSYHEPMVEAVGNGK 326
            |:|.|..||..||.||::|:                ::.||.|       .:.|:....:.....
Yeast   622 LRNEGYICPDNYNIADYLIDITFEAGPQGKRRRIRNISDLEAGTDTNDIDNTIHQTTFTSSDGTT 686

  Fly   327 VARWSPPA---------VEGETTTTKTDTTSGASSF----------YERDQFDEEISPKLLEA-- 370
            ...|:..|         :..|.....||...||:..          |:...:..|:|.::.|.
Yeast   687 QREWAHLAAHRDEIRSLLRDEEDVEGTDGRRGATEIDLNTKLLHDKYKDSVYYAELSQEIEEVLS 751

  Fly   371 ------------------KCSWWLQYKLLLVRMLIQMWRDKSYIKLKFYMNIVLALLVGSLYFGM 417
                              ...:..|..:|..|....|:|:...:...:.:.|:|:|.:|:||:.:
Yeast   752 EGDEESNVLNGDLPTGQQSAGFLQQLSILNSRSFKNMYRNPKLLLGNYLLTILLSLFLGTLYYNV 816

  Fly   418 GTSASKALFNFGF-----MFTIVIAYLYLPMMPVLLYFPTEINLLKREYNNQWYRLSSYYAAMVT 477
            ....|      ||     :|..::.|........|..|..|..:..:|.:|.:|...:||.:.:.
Yeast   817 SNDIS------GFQNRMGLFFFILTYFGFVTFTGLSSFALERIIFIKERSNNYYSPLAYYISKIM 875

  Fly   478 SKLPSMFILAVIYLS-IVYLMSSQPLEWFRFAMLFTIAFVTALTSDSFGLLISSRLSLVNAMFMG 541
            |::..:.::..|.|| |||.|:...::...|.....|..:       |.|.||..:..:..:|..
Yeast   876 SEVVPLRVVPPILLSLIVYPMTGLNMKDNAFFKCIGILIL-------FNLGISLEILTIGIIFED 933

  Fly   542 PVLAVPLILLSIYGIGYGGGTYISP------LMRFLMHLSYLRHSMEGLVASLYDYGRADTICED 600
            ...::.|.:|.:.|.....|.:|:.      ..::|.:.|...::.|.|:           |.|.
Yeast   934 LNNSIILSVLVLLGSLLFSGLFINTKNITNVAFKYLKNFSVFYYAYESLL-----------INEV 987

  Fly   601 TEIFCSFKK--------SKVLLAFLGFENMHYLWSLSCLMSFYLLFTVAAYFMIR 647
            ..:....:|        ...:|:..||...:.::.:..|..|.::|.:..|..::
Yeast   988 KTLMLKERKYGLNIEVPGATILSTFGFVVQNLVFDIKILALFNVVFLIMGYLALK 1042

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_608493.2	3a01204	67..654	CDD:273361	166/672 (25%)
ADP1	NP_009937.2	EGF_CA	<70..>90	CDD:473889
		3a01204	402..1042	CDD:273361	166/665 (25%)