DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4822 and ABCG39

DIOPT Version :9

Sequence 1:	NP_001033861.1	Gene:	CG4822 / 33170	FlyBaseID:	FBgn0031220	Length:	677	Species:	Drosophila melanogaster
Sequence 2:	NP_176867.2	Gene:	ABCG39 / 843013	AraportID:	AT1G66950	Length:	1454	Species:	Arabidopsis thaliana

Alignment Length:	684	Identity:	178/684 - (26%)
Similarity:	294/684 - (42%)	Gaps:	135/684 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 LPSWPAVNLQFSELCYVV--PDQTNASKTK----TILRRVNGMFHSHELTAIIGPSGAGKTTLLN 104
            ||..| ::|.|:.:.|.|  |.:..|...:    .:||.|.|.|....|||::|.||||||||::
plant   846 LPFQP-LSLAFNNVNYYVDMPSEMKAQGVEGDRLQLLRDVGGAFRPGILTALVGVSGAGKTTLMD 909

  Fly   105 LLAG--FGAVCESGEILVNNSPRDMRVFRKMSRYIMQTDVLDSQFTVLEMMILAANLKLGKELNL 167
            :|||  .|...| |.|.::..|::...|.::|.|..|.|:.....||.|.:|.:|.|:|..::::
plant   910 VLAGRKTGGYIE-GSISISGYPKNQTTFARVSGYCEQNDIHSPHVTVYESLIYSAWLRLSTDIDI 973

  Fly   168 KQKLEVIDEILGMLRLKDTLNTM-----AQKLSGGERKRLCIALELVNNPPVIFLDEPTTGLDDL 227
            |.:...::|::.::.||...|::     ...||..:||||.||:|||.||.:||:||||:|||..
plant   974 KTRELFVEEVMELVELKPLRNSIVGLPGVDGLSTEQRKRLTIAVELVANPSIIFMDEPTSGLDAR 1038

  Fly   228 SSSQCIALLKVLAAGGRTVICSIHTPSAKIFEMLDAVYVLAE-GQCVYQGK----GSNIVPFLK- 286
            :::..:..::.....||||:|:||.||..|||..|.:.::.. ||.:|.|.    ...:|.:.:
plant  1039 AAAIVMRTVRNTVDTGRTVVCTIHQPSIDIFESFDELLLMKRGGQVIYAGSLGHHSQKLVEYFEA 1103

  Fly   287 -------NFGLCCPITYNPADFIIEVACLEYGGSYHEPMVEAVGNGKVARWSPPAVEGETTTTKT 344
                   |.|      ||||.::::|..............:...|..:.|.:...::..:|
plant  1104 VEGVPKINDG------YNPATWMLDVTTPSMESQMSLDFAQIFSNSSLYRRNQELIKDLST---- 1158

  Fly   345 DTTSGASSFYERDQFDEEISPKLLEAKCSWWLQYKLLLVRMLIQMWRDKSYIKLKFYMNIVLALL 409
             ...|:...|.:.::.:..|   .:.|..:|.||        ...||...|..::|.|.:|:.:|
plant  1159 -PPPGSKDVYFKTKYAQSFS---TQTKACFWKQY--------WSYWRHPQYNAIRFLMTVVIGVL 1211

  Fly   410 VGSLYFGMGTSA--SKALFN-FGFMFTIVIAYLYLPMMPVLLYFPTEINLLKREYNNQWYRLSSY 471
            .|.:::.:||..  .:.|.| ||.|:..|:....|....|......|..:..||.....|....|
plant  1212 FGLIFWQIGTKTENEQDLNNFFGAMYAAVLFLGALNAATVQPAIAIERTVFYREKAAGMYSAIPY 1276

  Fly   472 YAAMVTSKLPSMFILAVIYLSIVYLM-----SSQPLEWFRFAMLFTIAFVT-------ALTSD-- 522
            ..:.|..::....|...:|..|:|.|     :.....||.:.||.:..:.|       |||.:
plant  1277 AISQVAVEIMYNTIQTGVYTLILYSMIGCNWTMAKFLWFYYYMLTSFIYFTLYGMMLMALTPNYQ 1341

  Fly   523 SFGLLISSRLSLVNAMFMGPVLAVPLILLSIYGIGYGGGTYISPL-MRFLMHLSYLRHSMEGLVA 586
            ..|:.:|..|||.| :|.|.::..|.|                |: .|:....:.:..::.||:.
plant  1342 IAGICMSFFLSLWN-LFSGFLIPRPQI----------------PIWWRWYYWATPVAWTLYGLIT 1389

  Fly   587 SLYDYGRADTICE-----DTEIFCSFKKSKVLLAFLGFEN--------MHYLWSLSCLMSFYLLF 638
            |  ..|..|::..     |.::....|:.      .|||:        :|..|.|..|.
plant  1390 S--QVGDKDSMVHISGIGDIDLKTLLKEG------FGFEHDFLPVVAVVHIAWILLFLF------ 1440

  Fly   639 TVAAYFMIRLRLKHSEVSPIFAYVIQLLTKYFNF 672
                               :|||.|    |:.||
plant  1441 -------------------VFAYGI----KFLNF 1451

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_001033861.1	ABCG_EPDR	51..276	CDD:213180	86/238 (36%)
		3a01204	67..654	CDD:273361	163/641 (25%)
		ABC2_membrane	381..587	CDD:279410	51/223 (23%)
ABCG39	NP_176867.2	PLN03140	14..1454	CDD:215599	178/684 (26%)
		ABC_trans_N	94..169	CDD:291196
		P-loop_NTPase	180..430	CDD:304359
		ABC2_membrane	531..737	CDD:279410
		PDR_assoc	744..810	CDD:285559
		ABCG_PDR_domain2	850..1088	CDD:213199	87/239 (36%)
		ABC2_membrane	1183..1388	CDD:279410	53/229 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100151
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810