DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4822 and ABCG24

DIOPT Version :9

Sequence 1:	NP_001033861.1	Gene:	CG4822 / 33170	FlyBaseID:	FBgn0031220	Length:	677	Species:	Drosophila melanogaster
Sequence 2:	NP_175745.4	Gene:	ABCG24 / 841775	AraportID:	AT1G53390	Length:	1109	Species:	Arabidopsis thaliana

Alignment Length:	716	Identity:	193/716 - (26%)
Similarity:	310/716 - (43%)	Gaps:	158/716 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 VKGSTTSQISSLQ-----YSSDINADSLEPDQSEDFQTVLGL-----------KYLPSWPAVNLQ 55
            |||.|.::|...|     |:.|........:|.....|..|:           ::|     :.|.
plant   449 VKGQTLAKIKKTQSQIFKYAYDRIEKEKAMEQENKNLTFSGIVKMATNSETRKRHL-----MELS 508

  Fly    56 FSELCYVVPDQTNASKTKTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLAGFGAVCE-SGEIL 119
            |.:|..     |..|..|.:||.|.|......:||::||||||||:||:.|||....|: ||.||
plant   509 FKDLTL-----TLKSNGKQVLRCVTGSMKPGRITAVMGPSGAGKTSLLSALAGKAVGCKLSGLIL 568

  Fly   120 VNNSPRDMRVFRKMSRYIMQTDVLDSQFTVLEMMILAANLKLGKELNLKQKLEVIDEI---LGML 181
            :|.....:..::|:..::.|.||:....||.|.:...|..:|..:|:...|:.|::.|   ||:.
plant   569 INGKQESIHSYKKIIGFVPQDDVVHGNLTVEENLWFHAKCRLPADLSKADKVLVVERIIDSLGLQ 633

  Fly   182 RLKDTLNTMAQK--LSGGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIALLKVLAAGGR 244
            .::.:|....:|  :|||:|||:.:.||:|..|.|:||||||:|||..||...:..|:..|..|.
plant   634 AVRSSLVGTVEKRGISGGQRKRVNVGLEMVMEPSVLFLDEPTSGLDSASSQLLLRALRHEALEGV 698

  Fly   245 TVICSIHTPSAKIFEMLDAVYVLAE-GQCVYQGKGSNIVPFLKNFGLCCPITYNPADFIIEVACL 308
            .:...:|.||..:|:..:.:.:||: |..||.|..:.:..:....|:..|...||.|:.|:|.
plant   699 NICMVVHQPSYTLFKTFNDLVLLAKGGLTVYHGSVNKVEEYFSGLGIHVPDRINPPDYYIDVL-- 761

  Fly   309 EYGGSYHEPMVEAVGNGKVA------RW------SPP------AVEGETTTTKTDTTS--GASSF 353
                   |.:|.::||..:.      ||      |.|      :..|..|.....|.|  .|...
plant   762 -------EGVVISMGNSGIGYKELPQRWMLHKGYSVPLDMRNNSAAGLETNPDLGTNSPDNAEQT 819

  Fly   354 YERDQF----------DEEISPKLLEAK-------CSWWLQYKLLLVRMLIQMWRDKSYIKLKFY 401
            :.|:.:          .::|....|:::       .|.|||||..|.|:..|..|: :.::...|
plant   820 FARELWRDVKSNFRLRRDKIRHNFLKSRDLSHRRTPSTWLQYKYFLGRIAKQRMRE-AQLQATDY 883

  Fly   402 MNIVLA-LLVGSLYFGMGTSASKALFNF-GFMFTIVIAYLYLPMMPVLLYFPTEINLLKREYNNQ 464
            :.::|| ..:|||     ..||...|.. |:::|| ||...|..:..|..|    :|.|..|
plant   884 LILLLAGACLGSL-----IKASDESFGAPGYIYTI-IAVSLLCKIAALRSF----SLDKLHY--- 935

  Fly   465 W------YRLSSYYAAMVTSKLPSMFILAVIYLSIVYLMSSQPLEWFRFAMLFTIAFVTALTSDS 523
            |      ...|:.:.|..|..:.::.:..::|||:.|..:: |...|....:..:..|..:|..:
plant   936 WRESASGMSSSACFLAKDTIDIFNILVKPLVYLSMFYFFTN-PRSTFFDNYIVLVCLVYCVTGIA 999

  Fly   524 FGLLISSRLSLVNAMFMGPVLA------VPLILLSIYGIGYGGGTYI------SPLMRFLMHLSY 576
            :.|          |:|:.|..|      :|::|           |.:      |.|:|.:..|||
plant  1000 YAL----------AIFLQPSTAQLFSVLLPVVL-----------TLVATQPKNSELIRIIADLSY 1043

  Fly   577 LRHSMEGLV---ASLYDYG-RADTICEDTEIFCSFKKSKVLLAFLGFE-NMHYLWSLSCLMSFYL 636
            .:.::|..|   |..| || ...|.|.      |..||       |:: |.   ||| |:|...|
plant  1044 PKWALEAFVIGNAQKY-YGVWMITRCG------SLMKS-------GYDINK---WSL-CIMILLL 1090

  Fly   637 L 637
            :
plant  1091 V 1091

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_001033861.1	ABCG_EPDR	51..276	CDD:213180	82/231 (35%)
		3a01204	67..654	CDD:273361	178/640 (28%)
		ABC2_membrane	381..587	CDD:279410	52/228 (23%)
ABCG24	NP_175745.4	EcfA2	504..736	CDD:224047	84/241 (35%)
		ABCG_EPDR	505..731	CDD:213180	82/230 (36%)
		ABC2_membrane	867..>1006	CDD:304374	37/163 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	121	1.000	Domainoid score	I1855
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820