DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4822 and ABCG19

DIOPT Version :9

Sequence 1:	NP_001033861.1	Gene:	CG4822 / 33170	FlyBaseID:	FBgn0031220	Length:	677	Species:	Drosophila melanogaster
Sequence 2:	NP_191073.1	Gene:	ABCG19 / 824679	AraportID:	AT3G55130	Length:	725	Species:	Arabidopsis thaliana

Alignment Length:	763	Identity:	181/763 - (23%)
Similarity:	323/763 - (42%)	Gaps:	173/763 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 SSVKGSTTSQISSLQYSSDI----------NADSLEPDQSEDFQTVLGLK--------------Y 45
            |..|.:.|...:..||.:.|          :.||.....|.|     |:|              |
plant     6 SGRKIAMTRVSAETQYITPIGSPTLDELLKDCDSFRKGDSGD-----GVKSDDPAHHIIDVEALY 65

  Fly    46 LPSWPAVNLQFSELCYVVPDQ-----TNASKTKTILRRVNGMFHSHELTAIIGPSGAGKTTLLNL 105
            :...|.| |.|:.|.|.|..:     :..:..||:|..|:|.....::.|::|.|||||:||::.
plant    66 VKPVPYV-LNFNNLQYDVTLRRRFGFSRQNGVKTLLDDVSGEASDGDILAVLGASGAGKSTLIDA 129

  Fly   106 LAG-------FGAVCESGEILVNNSPRDMRVFRKMSRYIMQTDVLDSQFTVLEMMILAANLKLGK 163
            |||       .|:|..:||.::.:     |:.:.:|.|:||.|:|....||.|.::.|:..:|.:
plant   130 LAGRVAEGSLRGSVTLNGEKVLQS-----RLLKVISAYVMQDDLLFPMLTVKETLMFASEFRLPR 189

  Fly   164 ELNLKQKLEVIDEILGMLRLKDTLNTMA-----QKLSGGERKRLCIALELVNNPPVIFLDEPTTG 223
            .|:..:|:|.::.::..|.|::..||:.     :.:|||||:|:.|.::::::|.|:||||||:|
plant   190 SLSKSKKMERVEALIDQLGLRNAANTVIGDEGHRGVSGGERRRVSIGIDIIHDPIVLFLDEPTSG 254

  Fly   224 LDDLSSSQCIALLKVLAAGGRTVICSIHTPSAKIFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNF 288
            ||..::...:.:||.:|..|..||.|||.|||:|.|:||.:.:|:.|:.|:.|..:::..|..:|
plant   255 LDSTNAFMVVQVLKRIAQSGSIVIMSIHQPSARIVELLDRLIILSRGKSVFNGSPASLPGFFSDF 319

  Fly   289 GLCCPITYNPADFIIEV------------ACLEYGGSYHEPMV---------------------E 320
            |...|...|.::|.:::            |.:::...:.:..:                     |
plant   320 GRPIPEKENISEFALDLVRELEGSNEGTKALVDFNEKWQQNKISLIQSAPQTNKLDQDRSLSLKE 384

  Fly   321 AVGNGKVARWSPPAVEGETTTTKTDTTSGASSFYERDQFDEEISPKLLEAKCSWWLQYKLLLVRM 385
            |: |..|:|....:....:..|..:|.|..:            :|.|.|.         .:|.:.
plant   385 AI-NASVSRGKLVSGSSRSNPTSMETVSSYA------------NPSLFET---------FILAKR 427

  Fly   386 LIQMW-RDKSYIKLKFYMNIVLALLVGSLYFGMG---TSASKALFNFGFMFTIVIAYLYLPMMPV 446
            .::.| |....:..:....:|...|:.::|:.:.   ..|.:.|..|.|:...:. |..|..:||
plant   428 YMKNWIRMPELVGTRIATVMVTGCLLATVYWKLDHTPRGAQERLTLFAFVVPTMF-YCCLDNVPV 491

  Fly   447 LLYFPTEINLLKREYNNQWYRLSSYYAAMVTSKLPSMFILAVIYLSIVY--LMSSQPLEWFRFAM 509
               |..|..:..||..:..||.|||..:.....||.:...::::.:|.:  :..|..||.|.|..
plant   492 ---FIQERYIFLRETTHNAYRTSSYVISHSLVSLPQLLAPSLVFSAITFWTVGLSGGLEGFVFYC 553

  Fly   510 LFTIAFVTALTSDSFGLLISSRLSLVNAMFMGPV--LAVPLILLSIYGIGYGGGTYIS----PLM 568
            |  :.:.:..:..|....||..:..:...:|..:  ||..|:|         .|.|::    |..
plant   554 L--LIYASFWSGSSVVTFISGVVPNIMLCYMVSITYLAYCLLL---------SGFYVNRDRIPFY 607

  Fly   569 RFLMH-LSYLRHSMEG-----------------------LVASLYDYGRA---DTICED-----T 601
            ....| :|.|::..|.                       |:..:.|.|:.   :|:.:.     |
plant   608 WTWFHYISILKYPYEAVLINEFDDPSRCFVRGVQVFDSTLLGGVSDSGKVKLLETLSKSLRTKIT 672

  Fly   602 EIFCSFKKSKVLLAFLGFENMHYLWSLSCLMSFY---LLFTVAAYFMI 646
            |..| .:....|||..|...:. .|  .||...:   |.|.:..||.:
plant   673 ESTC-LRTGSDLLAQQGITQLS-KW--DCLWITFASGLFFRILFYFAL 716

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_001033861.1	ABCG_EPDR	51..276	CDD:213180	83/241 (34%)
		3a01204	67..654	CDD:273361	161/672 (24%)
		ABC2_membrane	381..587	CDD:279410	48/241 (20%)
ABCG19	NP_191073.1	P-loop_NTPase	89..307	CDD:304359	77/222 (35%)
		3a01204	90..724	CDD:273361	161/673 (24%)
		ABC2_membrane	424..627	CDD:279410	47/217 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920