DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4822 and ABCG21

DIOPT Version :9

Sequence 1:	NP_001033861.1	Gene:	CG4822 / 33170	FlyBaseID:	FBgn0031220	Length:	677	Species:	Drosophila melanogaster
Sequence 2:	NP_001189973.1	Gene:	ABCG21 / 822149	AraportID:	AT3G25620	Length:	672	Species:	Arabidopsis thaliana

Alignment Length:	682	Identity:	197/682 - (28%)
Similarity:	322/682 - (47%)	Gaps:	79/682 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 TSQISSLQYSS--------DINADSLEPDQSEDFQTVLGLKYLPSWPAVNLQFSELCYVVPDQTN 68
            ||.:...::||        |.:.|...|.......:||.....|    :.|:|.||.|.:..||.
plant    22 TSPVQENRFSSPSHVNPCLDDDNDHDGPSHQSRQSSVLRQSLRP----IILKFEELTYSIKSQTG 82

  Fly    69 ASK----------TKTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLAGFGAVCESGEILVNNS 123
            ...          .:.:|:.|:|:....||.|::||||:|||||:..|||......||.:..|..
plant    83 KGSYWFGSQEPKPNRLVLKCVSGIVKPGELLAMLGPSGSGKTTLVTALAGRLQGKLSGTVSYNGE 147

  Fly   124 PRDMRVFRKMSRYIMQTDVLDSQFTVLEMMILAANLKLGKELNLKQKLEVIDEILGMLRLKDTLN 188
            |....|.|| :.::.|.|||....||:|.:...|.|:|.|||..|:|||.::.::..|.|....|
plant   148 PFTSSVKRK-TGFVTQDDVLYPHLTVMETLTYTALLRLPKELTRKEKLEQVEMVVSDLGLTRCCN 211

  Fly   189 T-----MAQKLSGGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIALLKVLAAGGRTVIC 248
            :     :.:.:|||||||:.|..|::.||.::.|||||:|||..::::.:|.|:.||.|||||:.
plant   212 SVIGGGLIRGISGGERKRVSIGQEMLVNPSLLLLDEPTSGLDSTTAARIVATLRSLARGGRTVVT 276

  Fly   249 SIHTPSAKIFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNFGLCCPITY-NPADFIIEVACLEYGG 312
            :||.||::::.|.|.|.||:||..:|.|....::.:..:.|.....:: |||||::::|......
plant   277 TIHQPSSRLYRMFDKVLVLSEGCPIYSGDSGRVMEYFGSIGYQPGSSFVNPADFVLDLANGITSD 341

  Fly   313 SYHEPMVEAVGNGKVARWSPPAVEGETTTTKTDTTSG------------ASSFYERDQFDEEISP 365
            :.....:|.  ||::.|..      |..:.|....|.            .|..:.:||.:..:..
plant   342 TKQYDQIET--NGRLDRLE------EQNSVKQSLISSYKKNLYPPLKEEVSRTFPQDQTNARLRK 398

  Fly   366 KLLEAK--CSWWLQYKLLLVRMLIQMWRDKSYIKLKFYMNIVLALLVGSLYFGMGTSASKALFNF 428
            |.:..:  .|||:|:.:||.|.|.:. ..:|:..|:.:|.:.::||.|.|::  .:..:......
plant   399 KAITNRWPTSWWMQFSVLLKRGLKER-SHESFSGLRIFMVMSVSLLSGLLWW--HSRVAHLQDQV 460

  Fly   429 GFMFTIVIAYLYLPMMPVLLYFPTEINLLKREYNNQWYRLSSYYAAMVTSKLPSMFILAVIYLSI 493
            |.:|...|.:.:.|:...:..||.|..:|.:|.::..|||||||.|.....||...||..|:::|
plant   461 GLLFFFSIFWGFFPLFNAIFTFPQERPMLIKERSSGIYRLSSYYIARTVGDLPMELILPTIFVTI 525

  Fly   494 VYLMSSQPLEWFRFAMLFTIAFVTALTSDSFGLLISSRL-SLVNAMFMGPVLAVPLILLSIYGIG 557
            .|.|.........|.|...|.....|.:...||.:.:.| ....|..:..||.:..:|
plant   526 TYWMGGLKPSLTTFIMTLMIVLYNVLVAQGVGLALGAILMDAKKAATLSSVLMLVFLL------- 583

  Fly   558 YGGGTYISPLMRFLMHLSYLRHS---MEGLVASLYDYGRADTICE-DTEIFCSFKKSKVLLAFLG 618
             .||.||..:..|:..|.|:..|   .:.||...|.:   |.:.| .:.:.||      ::.:.|
plant   584 -AGGYYIQHIPGFIAWLKYVSFSHYCYKLLVGVQYTW---DEVYECGSGLHCS------VMDYEG 638

  Fly   619 FENM---HYLWSLSCLMSFYLLFTVAAYFMIR 647
            .:|:   :.:|.:..|....||:.|.||..:|
plant   639 IKNLRIGNMMWDVLALAVMLLLYRVLAYLALR 670

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_001033861.1	ABCG_EPDR	51..276	CDD:213180	92/239 (38%)
		3a01204	67..654	CDD:273361	181/619 (29%)
		ABC2_membrane	381..587	CDD:279410	57/209 (27%)
ABCG21	NP_001189973.1	PLN03211	43..670	CDD:215634	191/659 (29%)
		P-loop_NTPase	89..304	CDD:304359	85/215 (40%)
		ABC2_membrane	416..615	CDD:279410	57/209 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.820