Protein Alignment CG4822 and ABCG2

DIOPT Version :9

• Sequence 1: NP_001033861.1
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_181272.1
• Gene: ABCG2 / 818312
• AraportID: AT2G37360
• Length: 755
• Species: Arabidopsis thaliana
• Alignment Length: 657
• Identity: 149/657 - (22%)
• Similarity: 283/657 - (43%)
• Gaps: 134/657 - (20%)

  Fly     2 ETASSVKGSTTSQISSLQYSSDINADSLEPDQSEDFQTVLGLKYLPSWPAVNLQFSELCYVVPDQ 66
            |:|||......|.|:|.  :|..|:.:..|..|           :.|.|.| |.|::|.|.|..|
plant    60 ESASSRALGIASPINSA--ASSFNSWASAPASS-----------ISSSPFV-LSFTDLTYSVKIQ 110

  Fly    67 --------------TNASKTKTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLAG-------FG 110
                          .::..||.:|..::|.....|:.|::|.||:||:||::.||.       .|
plant   111 KKFNPLACCRRSGNDSSVNTKILLNGISGEAREGEMMAVLGASGSGKSTLIDALANRIAKDSLRG 175

  Fly   111 AVCESGEILVNNSPRDMRVFRKMSRYIMQTDVLDSQFTVLEMMILAANLKLGKELNLKQKLEVID 175
            ::..:||:|      :..:.:.:|.|:||.|:|....||.|.::.:|..:|.:.|:.|:|...:.
plant   176 SITLNGEVL------ESSMQKVISAYVMQDDLLFPMLTVEETLMFSAEFRLPRSLSKKKKKARVQ 234

  Fly   176 EILGMLRLKDTLNTMA-----QKLSGGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIAL 235
            .::..|.|:....|:.     :.:|||||:|:.|..:::::|.::||||||:|||..|:...|.:
plant   235 ALIDQLGLRSAAKTVIGDEGHRGVSGGERRRVSIGNDIIHDPIILFLDEPTSGLDSTSAYMVIKV 299

  Fly   236 LKVLAAGGRTVICSIHTPSAKIFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNFGLCCPITYNPAD 300
            |:.:|..|..||.|||.||.:|..:||.:..|::|..||.|..:::..|...|....|...|..:
plant   300 LQRIAQSGSIVIMSIHQPSYRIMGLLDQLIFLSKGNTVYSGSPTHLPQFFSEFKHPIPENENKTE 364

  Fly   301 FIIE-VACLEYGGSYHEPMVE--------------------------------AVGNGKVARWSP 332
            |.:: :..|||.....:|:||                                ::..||:
plant   365 FALDLIRELEYSTEGTKPLVEFHKQWRAKQAPSYNNNNKRNTNVSSLKEAITASISRGKL----- 424

  Fly   333 PAVEGETTTTKTDTTSGASSFYERDQFDEEISPKLLEAKCSWWLQYKLLLVRMLIQMWRDKSYIK 397
              |.|.|....::.|....:|         .:|        :|::..::..|.::...|....:.
plant   425 --VSGATNNNSSNLTPSFQTF---------ANP--------FWIEMIVIGKRAILNSRRQPELLG 470

  Fly   398 LKFYMNIVLALLVGSLYFGMGTSASKALFNFGFMFTIVIAYLYLPMMPVLLYFPTEINLLKREYN 462
            ::....:|..:::.:::..:..|...|....|| |...::..:......:..|..|..:..||..
plant   471 MRLGAVMVTGIILATMFTNLDNSPKGAQERLGF-FAFAMSTTFYTCAEAIPVFLQERYIFMRETA 534

  Fly   463 NQWYRLSSYYAAMVTSKLPSMFILAVIYLSIVYLM-----SSQPLEWFRFAMLFTI----AFVTA 518
            ...||.|||..:.....:|::.:|:..:.:..:..     .:....:|.|.:|.:.    :|||.
plant   535 YNAYRRSSYVLSQSIISIPALIVLSASFAATTFWAVGLDGGANGFFFFYFTILASFWAGSSFVTF 599

  Fly   519 LTSDSFGLLISSRLSLVNAMFMGPVLAVPLILLSIYGIGYGGGTYIS----PLMRFLMH-LSYLR 578
            |:            .::..:.:|..:.|.::...:...|:    :||    |:.....| :|.::
plant   600 LS------------GVIPNVMLGFTVVVAILAYFLLFSGF----FISRDRIPVYWLWFHYISLVK 648

  Fly   579 HSMEGLV 585
            :..||::
plant   649 YPYEGVL 655

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_001033861.1	ABCG_EPDR	51..276	CDD:213180	79/250 (32%)
		3a01204	67..654	CDD:273361	129/578 (22%)
		ABC2_membrane	381..587	CDD:279410	36/219 (16%)
ABCG2	NP_181272.1	3a01204	95..754	CDD:273361	137/609 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.920