Protein Alignment CG4822 and abcg4b

DIOPT Version :9

• Sequence 1: NP_001033861.1
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_001104682.1
• Gene: abcg4b / 794238
• ZFINID: ZDB-GENE-080215-10
• Length: 644
• Species: Danio rerio
• Alignment Length: 624
• Identity: 239/624 - (38%)
• Similarity: 353/624 - (56%)
• Gaps: 49/624 - (7%)

  Fly    45 YLPSWPAVNLQFSELCYVVPDQTNASKT--KTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLA 107
            :||....|.|:|.||||.:.:.....|.  |.:|:.::|.|.|.||..|:|||||||:||:|:||
Zfish    50 HLPKRTTVELEFKELCYTIREGPWWKKQGYKALLKCLSGKFSSRELIGIMGPSGAGKSTLMNILA 114

  Fly   108 GFGAVCESGEILVNNSPRDMRVFRKMSRYIMQTDVLDSQFTVLEMMILAANLKLGKELNLKQKLE 172
            |:.....:|:||||...||.|.|||||.||||.|.|....:|.|.|:::|||||.:...:|:  |
Zfish   115 GYRETGMTGQILVNGKLRDPRTFRKMSCYIMQEDKLLPHLSVQEAMMVSANLKLNESSEVKK--E 177

  Fly   173 VIDEILGMLRLKDTLNTMAQKLSGGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIALLK 237
            :|.|||..|.|.:.::|....||||:.|||.|||||||||||:|.||||:|||..|..|.::|:|
Zfish   178 LIKEILTALGLHECVHTRTVSLSGGQCKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 242

  Fly   238 VLAAGGRTVICSIHTPSAKIFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNFGLCCPITYNPADFI 302
            .||.||||:||:||.||||:|||.|.:|:|::|||:|:|....::|:|:..||.||..:||||||
Zfish   243 SLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIYKGSVPYLIPYLRGLGLHCPTYHNPADFI 307

  Fly   303 IEVACLEYGGSYHEPMVEAVGNGKVARWSPPAVEGETTTTKTDTTSGASSFYERDQFDEEISPKL 367
            ||||..|| |..:..:.|||..|..|     ..|......||..||.|
Zfish   308 IEVASGEY-GDLNPVLFEAVQGGMCA-----LEEKCNCIDKTTVTSCA----------------- 349

  Fly   368 LEAKC--------------SWWLQYKLLLVRMLIQMWRDKSYIKLKFYMNIVLALLVGSLYFGMG 418
              |||              |...|:.:|..|..|.:.||:....|:...:|.:.:|:|.||..:|
Zfish   350 --AKCVKDPGHVESHTFATSSLTQFCILFKRTFITICRDQVLTHLRLMSHISIGVLIGLLYLNIG 412

  Fly   419 TSASKALFNFGFMFTIVIAYLYLPMMPVLLYFPTEINLLKREYNNQWYRLSSYYAAMVTSKLPSM 483
            ..|||...|.||:|..::..::..:||.:|.||.|:.:..||:.|.||.|.:||.|...:.:|..
Zfish   413 NDASKVFNNTGFLFFSMLFLMFGALMPTVLTFPLEMAVFLREHLNYWYSLKAYYLAKTMADIPFQ 477

  Fly   484 FILAVIYLSIVYLMSSQPLEWFRFAMLFTIAFVTALTSDSFGLLI-SSRLSLVNAMFMGPVLAVP 547
            .:..::|.||||.|:.||.|..|:.:...::..|||.:.|.|||: ::..||..|.|:|||..:|
Zfish   478 VLCPIMYCSIVYWMTEQPPEASRYLLFLALSICTALVAQSLGLLVGAASTSLQVATFVGPVTGIP 542

  Fly   548 LILLSIYGIGYGGGTYISPLMRFLMHLSYLRHSMEGLVASLYDYGRADTICEDTEIFCSFKKSKV 612
            ::|.|.:.:.:   ..|...:::..::||:|:..|.::.|:|...|.:..|...  .|.|::.:.
Zfish   543 VLLFSGFFVNF---DTIPEYLQWSSYVSYVRYGFEEVILSIYGMNRTERECPGR--VCKFQRPEE 602

  Fly   613 LLAFLGFENMHYLWSLSCLMSFYLLFTVAAYFMIRLRLK 651
            :|..|..|:.........|..|:::..:|.|.::|.::|
Zfish   603 VLQLLDVEDAKLYMDFIVLGIFFVILRLATYVVLRYKIK 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_001033861.1	ABCG_EPDR	51..276	CDD:213180	119/226 (53%)
		3a01204	67..654	CDD:273361	230/602 (38%)
		ABC2_membrane	381..587	CDD:279410	67/206 (33%)
abcg4b	NP_001104682.1	3a01204	42..644	CDD:273361	239/624 (38%)
		ABCG_EPDR	57..281	CDD:213180	119/225 (53%)
		ABC2_membrane	375..574	CDD:279410	66/201 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574362
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177791at33208
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.810