Protein Alignment CG4822 and abcg2a

DIOPT Version :10

• Sequence 1: NP_608493.2
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_073794813.1
• Gene: abcg2a / 735312
• ZFINID: ZDB-GENE-050517-35
• Length: 644
• Species: Danio rerio
• Alignment Length: 676
• Identity: 169/676 - (25%)
• Similarity: 308/676 - (45%)
• Gaps: 128/676 - (18%)

  Fly    42 GLKYLPSWPAVNLQFSELCYVVPDQTNASKTKT----ILRRVNGMFHSHELTAIIGPSGAGKTTL 102
            |:...||.....:.|..:.|.:..::...|:|:    ||..:||:. ...|.||:|.:|:||::.
Zfish    21 GVSSSPSRRGATVSFHNINYSLKMKSGFCKSKSTKKNILIGLNGIM-KPGLNAILGATGSGKSSF 84

  Fly   103 LNLL------AGFGAVCESGEILVNNSPRDMRVFRKMSRYIMQTDVLDSQFTVLEMMILAANLKL 161
            |::|      ||.     |||:|::.:|:... |:.:|.|::|.||:....||.|.:..:|.|:|
Zfish    85 LDVLAARKDPAGL-----SGEVLIDGAPQPPN-FKCLSGYVVQDDVVMGTLTVRENLRFSAALRL 143

  Fly   162 GKELNLKQKLEVIDEI---LGMLRLKDTL--NTMAQKLSGGERKRLCIALELVNNPPVIFLDEPT 221
            .|.:..::|.|.::.:   ||:.::.|:.  ..:.:.:|||||||..|.:||:.:|||:||||||
Zfish   144 PKSIKQREKDEKVERLIQELGLSKVADSRVGTQLIRGVSGGERKRTNIGMELIIDPPVLFLDEPT 208

  Fly   222 TGLDDLSSSQCIALLKVLAAGGRTVICSIHTPSAKIFEMLDAVYVLAEGQCVYQGKGSNIVPFLK 286
            ||||..:::..:.|||.:...|||:|.|||.|...|:.:.|::.:|..|:.||.|...:.:.:..
Zfish   209 TGLDASTANSVLMLLKKMGNNGRTIILSIHQPRYSIYRLFDSLTLLVGGKLVYHGPAQDALSYFS 273

  Fly   287 NFGLCCPITYNPADFIIEV-----ACLEYGGSYHE----------------PMVEAVGNGKVARW 330
            ..|..|....|||||.::|     :.:.....|.|                .:||......:.:.
Zfish   274 QIGYTCEPHNNPADFFLDVINGDSSAVTLNKLYEEVVDQDQLSSSLKGIEDRLVEEYQRSSIFQQ 338

  Fly   331 S----PPAVEGE--TTTTKTDTTSGASSFYERDQFDEEISPKLLEAKCSWWLQYKLLLVRMLIQM 389
            :    ...|:|:  :|..|:.|.:.::||                  |.   |:..:|.|....:
Zfish   339 THADLQRIVQGQDYSTRPKSRTITYSTSF------------------CH---QFHWVLKRTFRNL 382

  Fly   390 WRDKSYIKLKFYMNIVLALLVGSLYFGMGTSASKALFNFGFMFTIVIAYLYLPMMPVLLYFPTEI 454
            ..:......:..:.|.|||:||:::||:..::|......|.:|.|.....:..:....| |..|.
Zfish   383 MLNPQTSVAQIGVMIFLALVVGAIFFGVAENSSGIQNRMGALFFITTNQCFSSVSAAEL-FIAER 446

  Fly   455 NLLKREYNNQWYRLSSYYAAMVTSKLPSM-FILAVIYLSIVYLM-SSQPLEWFRFAMLFTIAFVT 517
            .|...||.:.:||:|.|:.:.:.|.:.:: .|.|||:..:.|.| ..:|.....|..||:|..|:
Zfish   447 KLFVHEYISGYYRVSVYFLSKILSDILTLRTIPAVIFSCVAYFMIGLKPAAEAFFIFLFSIIMVS 511

  Fly   518 --------ALTSDSFGLLISSRLSLVNAMFM----GPVLAVPLILLSIYGIGYGGGTYISPLMRF 570
                    |:::|...:.|::....::.:||    |.::.:|.:           .|:::    :
Zfish   512 YTATAMTLAISADQTVVAIANIFMTISFVFMMIFSGLLVNLPSV-----------ATWLN----W 561

  Fly   571 LMHLSYLRHSMEGLVASLY-------DYGRADTICEDTEIFCSFKKSKVLLAFLGFENMHY---- 624
            |.:.|..|:.:..|..:.:       :...:.::|...|            .||..:.:.|
Zfish   562 LKYFSIPRYGLSALQINEFTGLFFCDNRNNSGSVCSSGE------------EFLQEQGIDYSAWG 614

  Fly   625 LWSLSC---LMSFYLLFTVAAYFMIR 647
            ||....   :|:|  :|...||..:|
Zfish   615 LWQNHLALGIMTF--IFLCIAYLKLR 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_608493.2	3a01204	67..654	CDD:273361	164/651 (25%)
abcg2a	XP_073794813.1	None