Protein Alignment CG4822 and abcg2d

DIOPT Version :9

• Sequence 1: NP_001033861.1
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_009292498.3
• Gene: abcg2d / 735310
• ZFINID: ZDB-GENE-050517-38
• Length: 658
• Species: Danio rerio
• Alignment Length: 671
• Identity: 178/671 - (26%)
• Similarity: 309/671 - (46%)
• Gaps: 87/671 - (12%)

  Fly    29 LEPDQSEDFQTVLGLKYLPSWPAVNLQFSELCYVVPDQT-----NASKTKTILRRVNGMFHSHEL 88
            :||.:.:...||              .|..:.|.|..:|     ..:..|.||..:||:... .|
Zfish    29 MEPMKKQHGATV--------------SFHSIRYRVEQKTGPVCRRTTVQKEILLDLNGIMRP-GL 78

  Fly    89 TAIIGPSGAGKTTLLNLLAG----FGAVCESGEILVNNSPRDMRVFRKMSRYIMQTDVLDSQFTV 149
            .||:||:|:||::.|::|||    .|.   |||:|||.:.:... |:.:|.|::|.|::....||
Zfish    79 NAILGPTGSGKSSFLDVLAGRKDPAGL---SGEVLVNGALQPAN-FKCLSGYVVQDDIVMGTLTV 139

  Fly   150 LEMMILAANLKLGKELNLKQKLEVIDEILGMLRLKDTLNT-----MAQKLSGGERKRLCIALELV 209
            .|.:..:|.|:|...::.::|...::.::..|.|....::     :.:.:|||||||..|.:||:
Zfish   140 RENLSFSAALRLSSHVSPREKEARVNHLISELGLNKVADSKVGTQIIRGISGGERKRTSIGMELI 204

  Fly   210 NNPPVIFLDEPTTGLDDLSSSQCIALLKVLAAGGRTVICSIHTPSAKIFEMLDAVYVLAEGQCVY 274
            .:|.|:||||||||||..::...:.|||.:|..|||:|.|||.|...|:.:.|::.:||.|:.||
Zfish   205 IDPSVLFLDEPTTGLDASTAHSVLLLLKRMAGQGRTIIMSIHQPRFSIYRLFDSLTLLANGKQVY 269

  Fly   275 QGKGSNIVPFLKNFGLCCPITYNPADFIIEVACLEYGGSYHEPMVEAVGNGKVARWSPPAVEGET 339
            .|...:.:.:..|.|..|....|||||.::|    ..||    .|..:.|...|.....||..::
Zfish   270 HGPAQDALDYFSNIGYACEAHNNPADFFLDV----INGS----SVTKIQNNGDAECDVSAVSRQS 326

  Fly   340 TTTKTDTTSGASSFYE--RDQFDEEISPK-----LLEAKC-------SWWLQYKLLLVRMLIQMW 390
            ...:......:.||..  |.:.|..|..|     .:.|:|       |:..|.:.:|.|....:.
Zfish   327 VEDQLMEKYRSCSFARAVRAELDHIIQTKDSSSSSVAAECHSITYSSSFCQQLRWVLWRTFWNLM 391

  Fly   391 RDKSYIKLKFYMNIVLALLVGSLYFGMGTSASKALFNFGFMFTIVIAYLYLPMMPVLLYFPTEIN 455
            .:......:..:..::|.:||::::|:....|.....||.:|.|.....:..:....| |.||..
Zfish   392 LNPQTSVAQLAVTTLMAAIVGAIFYGVKDDQSGIQNRFGVLFFITTNQCFSTLSAAEL-FITERK 455

  Fly   456 LLKREYNNQWYRLSSYYAAMVTS------KLPSMFILAVIYLSIVYLMSSQPLEWFRFAMLFTIA 514
            |...||.:.:||:|.::.:.:.|      .:||:....|:|    :::..:|.....|..:.|:.
Zfish   456 LFIHEYTSGYYRVSVFFLSKILSDIITQRTIPSVLFSCVVY----FMIGLKPTASAFFIFMLTVI 516

  Fly   515 FVTALTSDSFGLLISSRLSLVNAMFMGPVLAVPLILLSIYGIGYGGGTYISPLMRFLMHLSYL-- 577
            .|:. |:.:..:.||:..|:|....:  ::.|..|.:.|:.   |....:..:|.:|..|.||
Zfish   517 LVSC-TAAAMAMAISADQSVVAVANI--LMTVSFIFMMIFS---GLLVNLKSIMDWLSWLKYLSI 575

  Fly   578 -RHSMEGLVASLYDYGRADTICEDTEIFCSFKKSKVLLA----FLGFENMHY----LW-SLSCLM 632
             |:.:|.|..:.: .|.  :.|.:.....:...:.||:.    .|.|:.:.|    || :...|.
Zfish   576 PRYGLEALEINEF-VGL--SFCGNVSESLASPAAHVLMCTGEQHLTFQGIDYSSWGLWQNHVALT 637

  Fly   633 SFYLLFTVAAYFMIRLRLKHS 653
            ...|:|.:.||..:|...|.|
Zfish   638 VMTLIFLIIAYIKLRFISKFS 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_001033861.1	ABCG_EPDR	51..276	CDD:213180	83/238 (35%)
		3a01204	67..654	CDD:273361	171/633 (27%)
		ABC2_membrane	381..587	CDD:279410	47/214 (22%)
abcg2d	XP_009292498.3	PRK10535	56..658	CDD:333000	169/628 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574365
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.850