Protein Alignment CG4822 and abcg2

DIOPT Version :9

• Sequence 1: NP_001033861.1
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_012819987.2
• Gene: abcg2 / 734088
• XenbaseID: XB-GENE-991895
• Length: 682
• Species: Xenopus tropicalis
• Alignment Length: 662
• Identity: 166/662 - (25%)
• Similarity: 307/662 - (46%)
• Gaps: 146/662 - (22%)

  Fly    73 KTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLA------GFGAVCESGEILVNNSPRDMRVFR 131
            :.||..|||:... .|.||:||:|:||::||::||      |.     ||::||:..|:... |:
 Frog    80 RVILNDVNGIMRP-GLNAILGPTGSGKSSLLDVLAARKDPNGL-----SGQVLVDGEPQPSN-FK 137

  Fly   132 KMSRYIMQTDVLDSQFTVLEMMILAANLKLGKELNLKQKLEVIDEI---LGMLRLKDTL--NTMA 191
            .:|.|::|.||:....::.|.:..:|.|:|.:.:..|:|.|.|:::   ||:.::.|:.  ....
 Frog   138 CLSGYVVQDDVVMGTLSIRENLQFSAALRLPRSVKQKEKDERINQVIKELGLTKVADSKVGTQFI 202

  Fly   192 QKLSGGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIALLKVLAAGGRTVICSIHTPSAK 256
            :.:|||||||..|.:||:.:|.::||||||||||..:::..:.|||.::..|:|:|.|||.|...
 Frog   203 RGVSGGERKRTNIGMELITDPGILFLDEPTTGLDASTANAVLLLLKRMSRQGKTIIFSIHQPRYS 267

  Fly   257 IFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNFGLCCPITYNPADFIIEVACLEYGGSYHEPMVEA 321
            ||.:.|::.:||.|:.::.|...:.:.:....|..|....|||||.:::
 Frog   268 IFRLFDSLTLLAGGRLLFHGPSRDALDYFTGLGYECESHNNPADFFLDI---------------- 316

  Fly   322 VGNGKVARWSPPAVEGETTTTKTDTTSGASSFYERDQFDEEISPKLLE------AKCSWWLQYKL 380
                         :.|::|....:.........|:.:.::..|..::|      ...|::|:.|.
 Frog   317 -------------INGDSTAVALNKLEDVELENEQKEVNDNGSKTVVENLSEQFCTTSYYLETKA 368

  Fly   381 LLVRMLI--------------------------------QMWRDKSYIKLKFYMNIVLALLVGSL 413
            .|.:|.:                                .:||:......:..:.:||||:||::
 Frog   369 ELEKMSLGKKIKSNFFARQITYNTSFLHQLKWVCKRSFKNLWRNPQASIAQVMVTLVLALIVGAI 433

  Fly   414 YFGMGTSASKALFNFGFMFTIVIAYLYLPMMPVLLYFPTEINLLKREYNNQWYRLSSY-YAAMVT 477
            :||:....|......|.:|.:.....:..:..:.| |..|..:...||.:.:||||:| :|.:.|
 Frog   434 FFGVKEDVSGIQNRVGSLFFVTTNQCFSSVSAIEL-FIVEKKIFIHEYISGYYRLSAYFFAKLFT 497

  Fly   478 SKLPSMFILAVIYLSIVYLMSSQPLEWFR------FAMLFTIAFVTALTSDSFGLLISSRLSLVN 536
            ..||...:.::|:.|::|.|..     |:      |.|:||:..: |.|:.|..|.:::...
 Frog   498 DLLPMRTLPSIIFTSVIYFMIG-----FKATAGAFFTMMFTLMMI-AYTAASMALAVAAGQD--- 553

  Fly   537 AMFMGPVLAVPLILLSI---YGIGYGG-GTYISPLMRFLMHLSYLRHSMEGLVA-SLYDY----- 591
                  |:||..:|::|   :.|.:.| ...::.:|.::..|.|......||.| .:.::
 Frog   554 ------VVAVANLLMTICFVFMIIFSGLLVNLTSVMDWISWLKYFSIPRYGLTALQINEFTNLNF 612

  Fly   592 --GRADTI-----CEDTEIF--CSFKKSKVLLAFLGFENMHY----LW----SLSCLMSFYLLFT 639
              |...||     |..:..|  |:.::      :|..:.:.:    ||    :|:|:::.:|  |
 Frog   613 CNGLNTTIQGNPNCTGSSPFGTCTGEE------YLTVQGIDFSTWGLWQNHLALACMIAIFL--T 669

  Fly   640 VA---AYFMIRL 648
            :|   .|||.:|
 Frog   670 IAYLKLYFMKKL 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_001033861.1	ABCG_EPDR	51..276	CDD:213180	77/213 (36%)
		3a01204	67..654	CDD:273361	166/662 (25%)
		ABC2_membrane	381..587	CDD:279410	55/249 (22%)
abcg2	XP_012819987.2	3a01204	73..675	CDD:273361	162/654 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010