DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4822 and Abca14

DIOPT Version :9

Sequence 1:	NP_001033861.1	Gene:	CG4822 / 33170	FlyBaseID:	FBgn0031220	Length:	677	Species:	Drosophila melanogaster
Sequence 2:	XP_017167760.1	Gene:	Abca14 / 67928	MGIID:	2388708	Length:	1719	Species:	Mus musculus

Alignment Length:	309	Identity:	75/309 - (24%)
Similarity:	135/309 - (43%)	Gaps:	48/309 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 SSDINADSLEPDQSEDFQTVLGLKYLPSWPAVN-----LQFSELCYVVPDQTNASKTKTILRRVN 80
            |.:::..|.|.|...:.:|:|.    ..|.::|     .:..::.:.:|       ....:|.::
Mouse  1362 SEELSGYSEEEDVQNERETILN----HPWRSLNSTVLIKELIKIYFKIP-------PTLAVRNIS 1415

  Fly    81 GMFHSHELTAIIGPSGAGKTTLLNLLAGFGAVCESGEILVN--NSPRDMRVFRKMSRYIMQTDVL 143
            ......|...::|.:||||||...:|.| ..:..||::.:.  :..|::...|....|..|.|.|
Mouse  1416 VAIQKEECFGLLGLNGAGKTTTFKILTG-EEIATSGDVFIEGYSITRNILKVRSKVGYCPQFDAL 1479

  Fly   144 DSQFTVLEMMILAANLKLGKELNLKQKLEVIDEILGMLRLKDTLNTMAQKLSGGERKRLCIALEL 208
            ....|..|::.:.|.:....|.:::   ..:|.:|.||.||...:.....||||.::||..|:.:
Mouse  1480 LDYMTSREILTMYARVWGIPENSIR---AYVDNLLKMLYLKPQADKFIYTLSGGNKRRLSTAIAI 1541

  Fly   209 VNNPPVIFLDEPTTGLDDLSSSQCIALLKVLAAGGRTVICSIHTPSAKIFEMLDA----VYVLAE 269
            :.|..|:|||||:||:|.|:.......:......|:.:|.:.|:     .|..:|    :.::.:
Mouse  1542 MGNSTVVFLDEPSTGMDPLARRMLWNAVIKTRESGKVIIITSHS-----MEECEALCTRLAIMVQ 1601

  Fly   270 GQCVYQGKGSNIVPFLKN-FGLCCPIT------------YNPADFIIEV 305
            |:.|..|...:    ||| ||....:|            .:..|||.||
Mouse  1602 GKFVCLGSPQH----LKNKFGNIYTMTIKFKTDTDDNTVQDLKDFIAEV 1646

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_001033861.1	ABCG_EPDR	51..276	CDD:213180	56/235 (24%)
		3a01204	67..654	CDD:273361	66/258 (26%)
		ABC2_membrane	381..587	CDD:279410
Abca14	XP_017167760.1	rim_protein	<128..1709	CDD:130324	75/309 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000