Protein Alignment CG4822 and abcg2b

DIOPT Version :10

• Sequence 1: NP_608493.2
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_001034155.1
• Gene: abcg2b / 570453
• ZFINID: ZDB-GENE-050517-36
• Length: 618
• Species: Danio rerio
• Alignment Length: 671
• Identity: 192/671 - (28%)
• Similarity: 310/671 - (46%)
• Gaps: 124/671 - (18%)

  Fly    40 VLGLKYLPSW-----------PAVNLQFSELCYVVPDQ----TNASKTKTILRRVNGMFHSHELT 89
            |..:|.||:.           |...|.:..:.|.:.:.    ...:..:.||:.|:|:..: .|.
Zfish     3 VCEIKMLPALESDGATVHVKVPGPILTYQNIHYCIRESRGLCCKKAPERDILKNVSGIMKT-GLN 66

  Fly    90 AIIGPSGAGKTTLLNLLAG----FGAVCESGEILVNNS--PRDMRVFRKMSRYIMQTDVLDSQFT 148
            ||:|.:|:|||:||:::||    .|  ..||::||:|.  ..|:|:   ||.|::|.|||....|
Zfish    67 AIMGATGSGKTSLLDVMAGRKDPRG--LRSGQVLVDNKLVTSDLRL---MSAYVVQDDVLMGTLT 126

  Fly   149 VLEMMILAANLKLGKE----LNLKQKLEVIDEILGMLRLKDT-LNT-MAQKLSGGERKRLCIALE 207
            |.|.::.:.||:|.:|    .:.|:|:|.|.|.||:....|| :.| ..:.:|||||||..|.:|
Zfish   127 VRENLLFSGNLRLPREQFSSADKKKKVESIIEELGLEDCADTKIGTEFIRGVSGGERKRCSIGME 191

  Fly   208 LVNNPPVIFLDEPTTGLDDLSSSQCIALLKVLAAGGRTVICSIHTPSAKIFEMLDAVYVLAEGQC 272
            |:.:|.::||||||||||..:::..||||..|:.||||:|.|||.|...||.:.|.:.::.:|:.
Zfish   192 LITSPTLLFLDEPTTGLDSNTANSIIALLHRLSRGGRTIIFSIHQPRYSIFRLFDYLTLMHKGET 256

  Fly   273 VYQGKGSNIVPFLKNFGLCCPITYNPADFIIEVACLEYGGSYHEPMVEAVGNGKVARWSPPAVEG 337
            ||.|.....:.:.::.|.......|||||.:::.                 ||:
Zfish   257 VYAGPAGKAIDYFQSLGYERDAFNNPADFFLDIT-----------------NGE----------- 293

  Fly   338 ETTTTKTDTTSGASSFYERDQF----DEEI------SPKLLEAK-------CSWWLQYKLLLVRM 385
              |.|...|....:..|...||    |||:      |..|.|||       .|:..|.|::..|.
Zfish   294 --TATSMPTEKSLAELYRESQFCTAVDEELKCITGPSDSLSEAKSKAPSYVTSFSYQLKVVCWRT 356

  Fly   386 LIQMWRDKSYIKLKFYMNIVLALLVGSLYFGMGTSASKALFN-FGFMFTIVIAYLYLPMMPVLLY 449
            .:.:.|:......:..|||:.|||:|.:|:.|..:..:||.| .|..|.::|..::..:..|.|
Zfish   357 GLNVVRNPQTSYAQIAMNILFALLIGLVYYQMPLTLPEALQNRIGAFFFLIINMVFGNLSAVEL- 420

  Fly   450 FPTEINLLKREYNNQWYRLSSYYAAMV-TSKLPSMFILAVIYLSI-VYLMSSQPLEWFRFAMLFT 512
            |..|..:...|.:..:||.|.|:.:.| ...||:..:..:|:.|| .|:|...|..........|
Zfish   421 FINERAIFVHENSGGYYRTSVYFLSKVFVDLLPNRIVPILIFSSISYYMMGLNPAFTSFLCFALT 485

  Fly   513 IAFVTALTSDSFGLLISSRLSLVNAMFMGPVLAV-PLILLSIYGIGYGGGTYISPLMRFLMHLSY 576
            ::.| :|...|...|:|:.   |:...|..:|.| |.:.:.::      |.::..|...|..||:
Zfish   486 VSLV-SLAGVSLAFLVSAS---VSTFAMANILVVLPFVFMMVF------GGFLVNLNSMLNWLSW 540

  Fly   577 LRHSMEGLVASLYDYG-RADTICEDTEIFCSFKKSKVLLA---------FLGFENMHY-LWSL-- 628
            |:.:      |::.|| .|.||.|        .|..||.:         :|..:.:.| :|..
Zfish   541 LKWT------SIFKYGLDAVTINE--------MKGLVLYSGNATLPGELYLESQGIDYSVWGFWQ 591

  Fly   629 --SCLMSFYLLFTVAAYFMIR 647
              ..|:...|:....||..:|
Zfish   592 NEVALLGIVLVCMTFAYIQLR 612

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_608493.2	3a01204	67..654	CDD:273361	185/629 (29%)
abcg2b	NP_001034155.1	3a01204	41..616	CDD:273361	185/633 (29%)