Protein Alignment CG4822 and abcg4a

DIOPT Version :10

• Sequence 1: NP_608493.2
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: XP_687685.2
• Gene: abcg4a / 564842
• ZFINID: ZDB-GENE-050517-39
• Length: 641
• Species: Danio rerio
• Alignment Length: 611
• Identity: 246/611 - (40%)
• Similarity: 366/611 - (59%)
• Gaps: 22/611 - (3%)

  Fly    45 YLPSWPAVNLQFSELCYVVPDQT--NASKTKTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLA 107
            :||....|:|:|:||.|.:.:..  .....|.:|:.::|.|.|.||..|:|||||||:||:|:||
Zfish    46 HLPRRSTVDLEFTELSYTIREGPCWRRRGFKALLKCLSGKFCSRELIGIMGPSGAGKSTLMNILA 110

  Fly   108 GFGAVCESGEILVNNSPRDMRVFRKMSRYIMQTDVLDSQFTVLEMMILAANLKLGKELNLKQKLE 172
            |:......|:||||..|||:|.|||||.||||.|:|....|..|.|:::|||||.:  |::.|.|
Zfish   111 GYRETGMKGQILVNGRPRDLRTFRKMSCYIMQDDMLLPHLTTREAMMVSANLKLNE--NMEVKKE 173

  Fly   173 VIDEILGMLRLKDTLNTMAQKLSGGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIALLK 237
            :::|||..|.|::...|....||||:.|||.|||||||||||:|.||||:|||..|..|.::|:|
Zfish   174 LVNEILTALGLQECAQTRTISLSGGQCKRLAIALELVNNPPVMFFDEPTSGLDSASCFQVVSLMK 238

  Fly   238 VLAAGGRTVICSIHTPSAKIFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNFGLCCPITYNPADFI 302
            .||.||||:||:||.||||:|||.|.:|:|::|||:|:|....::|:|||.||.||..:||||||
Zfish   239 SLAQGGRTIICTIHQPSAKLFEMFDKLYILSQGQCIYKGTVPYLIPYLKNLGLHCPTYHNPADFI 303

  Fly   303 IEVACLEYGGSYHEPMVEAVGNGKVARWSPPAVEGETTTTKTD-TTSGASSFYERDQFDEEISPK 366
            ||||..|| |..:..:.|||..|..:..|.     :.::.|.| |||..|..|....:.|:.:
Zfish   304 IEVASGEY-GDLNPVLFEAVQGGLCSDDSK-----KNSSDKNDPTTSCPSQCYPDSGYIEKHT-- 360

  Fly   367 LLEAKCSWWLQYKLLLVRMLIQMWRDKSYIKLKFYMNIVLALLVGSLYFGMGTSASKALFNFGFM 431
               ...|...|:.:|..|..|.:.||.....|:...::.:.:|:|.||..:|..|||...|.||:
Zfish   361 ---FATSTLTQFCILFKRTFITICRDVVLTHLRVMSHLCIGVLIGLLYLNIGNDASKVFNNTGFL 422

  Fly   432 FTIVIAYLYLPMMPVLLYFPTEINLLKREYNNQWYRLSSYYAAMVTSKLPSMFILAVIYLSIVYL 496
            |..::..::..:||.:|.||.|:.:..||:.|.||.|.:||.|...:.:|...|..::|.||||.
Zfish   423 FFSMLFLMFAALMPTVLTFPLEMGVFIREHLNYWYSLKAYYLAKTMADIPFQVICPIMYCSIVYW 487

  Fly   497 MSSQPLEWFRFAMLFTIAFVTALTSDSFGLLI-SSRLSLVNAMFMGPVLAVPLILLSIYGIGYGG 560
            |:.||.|..|:.:...::..|||.:.|.|||| ::..||..|.|:|||.|:|::|.|.:.:.:
Zfish   488 MTEQPPEAGRYLLFMALSTSTALVAQSLGLLIGAASTSLQVATFVGPVSAIPVLLFSGFFVNF-- 550

  Fly   561 GTYISPLMRFLMHLSYLRHSMEGLVASLYDYGRADTICEDTEIFCSFKKSKVLLAFLGFENMHYL 625
             ..|...:::..::||:|:..||::.|:|...|::..|..  |.|.|:|.:.:|..|..|:....
Zfish   551 -DTIPKYLQWSSYVSYVRYGFEGVILSIYGMNRSELECPG--IVCKFQKPEEVLQLLDVEDAKLY 612

  Fly   626 WSLSCLMSFYLLFTVAAYFMIRLRLK 651
            .....|..|:|:..:|.||::|.::|
Zfish   613 VDFMVLGVFFLVLRLATYFVLRYKVK 638

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_608493.2	3a01204	67..654	CDD:273361	238/589 (40%)
abcg4a	XP_687685.2	3a01204	38..641	CDD:273361	246/611 (40%)