Protein Alignment CG4822 and abcg5

DIOPT Version :9

• Sequence 1: NP_001033861.1
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_001122162.1
• Gene: abcg5 / 557317
• ZFINID: ZDB-GENE-050517-40
• Length: 652
• Species: Danio rerio
• Alignment Length: 694
• Identity: 168/694 - (24%)
• Similarity: 288/694 - (41%)
• Gaps: 139/694 - (20%)

  Fly     1 METASSVKGSTTSQISSLQYSSDINADSLEPDQSEDFQTVLGLKYLPSWPAVNLQFSELCYVVP- 64
            ||||.|                  |.|.:||      .:.|.:|        |:.:|....|.|
Zfish    26 METARS------------------NPDYIEP------SSCLSVK--------NVSYSVSERVGPW 58

  Fly    65 -DQTNASK--TKTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLAG----FGAVCESGEILVNN 122
             |.::..|  |:.||..|:....|.::..|:|.||:||||||:.:||    .|.:  .||:.||.
Zfish    59 WDLSSFRKKWTRQILNEVSFHLDSGQIMGILGNSGSGKTTLLDAIAGRIGNSGNL--QGEVFVNG 121

  Fly   123 SPRDMRVFRKMSRYIMQTDVLDSQFTVLEMMILAANLKLGK---ELNLKQKLEVIDEI-LGMLRL 183
            .......|:....|::|:|.|.|..||.|.:...|.|.|.|   |...|:...|:.|: ||.:..
Zfish   122 RKLKREQFQDCFSYVLQSDNLLSYLTVEETLTYTAQLALRKHSAEAIRKKVTAVMAELSLGHVAH 186

  Fly   184 KDTLNTMAQKLSGGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIALLKVLAAGGRTVIC 248
            ......:...:|||||:|:.||.:|:.:|.||.|||||||||.::::|.:.||..||...|.||.
Zfish   187 SVIGGRVFPGISGGERRRVSIASQLLQDPKVILLDEPTTGLDSMTANQIVMLLAELARRDRIVIV 251

  Fly   249 SIHTPSAKIFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNFGLCCPITYNPADFIIEVACLEYGGS 313
            :||.|.:::|.:.:.:.::::|:.|:.|:...:|.|..:.|..||...||.|..:::..::
Zfish   252 TIHQPRSELFRIFNRIAIMSQGELVFCGEPHKMVDFFSSCGYECPEYCNPFDIYVDLTSVD---- 312

  Fly   314 YHEPMVEAVGNGKVARWSPPAVEGETTTTKT--DTTSGASSFYERDQFDEEISPKLLEAKCSW-- 374
                          .|.|    |.|..|.:.  |.||.    |:..:....:..| :|..|..
Zfish   313 --------------TRCS----EREAATYRRMHDITSA----YQNSEIYTNMQEK-IEQSCQRPD 354

  Fly   375 --WLQYK------------LLLVRMLIQMWRDKSYIKLKFYMNIVLALLVGSLYFGMGTSASKAL 425
              .:.:|            :||.|....:.||:..|.::...|::..|.:......:|...:|..
Zfish   355 KPMIPFKSKESPNCISKLGVLLRRTFRNVSRDRMGILMRLSQNLIYGLFIAFFLMRLGKDVTKGA 419

  Fly   426 F--NFGFMFTIVIAYLYLPMMPVLLYFPTEINLLKREYNNQWYRLSSYYAAMVTSKLPSMFILAV 488
            .  ..|.::..:.|..|..|:..:..||....:..:|..:..|:....:.|.:...||...|...
Zfish   420 VQDRIGLIYQSMGASPYTGMLNAVALFPALRAISDQESKDGLYQKWQMFLAYIIHILPFSIISVF 484

  Fly   489 IYLSIVYL---MSSQPLEWFRFAMLFTIAFVTALTSDSFGLLISSRLSLVNAMFMGPVLAVPLIL 550
            |:.|.:|.   |:..|:   ||.....:..|..:..:...|::...:...|.:..|      :.|
Zfish   485 IFASFLYWTVGMNPDPV---RFLCFSAVVMVPHIIGELLTLVLLGVVQDPNMVNSG------VAL 540

  Fly   551 LSIYGIGYGGG-----TYISPLMRFLMHLSYLRHSMEGLVAS----------------------- 587
            |:|.||..|.|     ..:..:.::|.:|::.::..|.|:.:
Zfish   541 LNIAGIMVGSGFLRGFKQMPVVFQWLSYLTFQKYGCELLIVTEFYGLNFTCTPIAGLPGECLVDS 605

  Fly   588 ---LYDYGRADTICEDTEIFC---SFKKSKVLLAFLGFENMHYL 625
               :.|.|....:...|:.|.   :|..:.|:|..:.|:...:|
Zfish   606 GNMIIDQGYPGALSRYTQDFLLLYAFLPALVILGIISFKIRDHL 649

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_001033861.1	ABCG_EPDR	51..276	CDD:213180	82/236 (35%)
		3a01204	67..654	CDD:273361	152/626 (24%)
		ABC2_membrane	381..587	CDD:279410	44/215 (20%)
abcg5	NP_001122162.1	3a01204	50..645	CDD:273361	155/632 (25%)
		ABCG_White	53..279	CDD:213201	80/227 (35%)
		ABC2_membrane	375..582	CDD:279410	44/215 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.820