Protein Alignment CG4822 and abcg1

DIOPT Version :9

• Sequence 1: NP_001033861.1
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_001103924.1
• Gene: abcg1 / 556979
• ZFINID: ZDB-GENE-070424-84
• Length: 673
• Species: Danio rerio
• Alignment Length: 625
• Identity: 250/625 - (40%)
• Similarity: 370/625 - (59%)
• Gaps: 49/625 - (7%)

  Fly    45 YLPSWPAVNLQFSELCYVVPDQTNASKT--KTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLA 107
            |||..||||::|.:|.|.||:.....|.  ||:|:.::|.|....|.||:|||||||:||:|:||
Zfish    75 YLPRRPAVNIEFKDLSYSVPEGPWWRKKGYKTLLKGISGNFTGGALVAIMGPSGAGKSTLMNILA 139

  Fly   108 GFGAVCESGEILVNNSPRDMRVFRKMSRYIMQTDVLDSQFTVLEMMILAANLKLGKELNLKQKLE 172
            |:......||||:|..|||:|.|||:|.||||.|:|....||.|.|:::|||||.::  .:.:.|
Zfish   140 GYRETGMKGEILINGHPRDLRSFRKVSCYIMQDDMLLPHLTVQEAMMVSANLKLQEK--DEGRRE 202

  Fly   173 VIDEILGMLRLKDTLNTMAQKLSGGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIALLK 237
            ::.|||..|.|.:...|....||||:||||.|||||||||||:|.||||:|||..|..|.::|:|
Zfish   203 MVREILTALGLLECAKTRTSHLSGGQRKRLAIALELVNNPPVMFFDEPTSGLDSSSCFQVVSLMK 267

  Fly   238 VLAAGGRTVICSIHTPSAKIFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNFGLCCPITYNPADFI 302
            .||.|||||||:||.||||:||:.|.:|||::|||:|:||.|:::|:|::.||.||..:||||||
Zfish   268 ALAQGGRTVICTIHQPSAKVFELFDKLYVLSQGQCIYRGKVSSLIPYLRDLGLSCPTYHNPADFI 332

  Fly   303 IEVACLEYGGSYHEPMVEAV--------------GNG--KVARWSPPAVEGETTTTKTDTTSGAS 351
            :|||..|||..... :|:||              |||  ....|..|:.|      ::.::.|..
Zfish   333 MEVASGEYGDQTAR-LVKAVQEHKCEKDYKTEMNGNGVHNPFLWHRPSDE------ESSSSEGCH 390

  Fly   352 SFYERDQFDEEISPKLLEAKCSWWLQYKLLLVRMLIQMWRDKSYIKLKFYMNIVLALLVGSLYFG 416
            ||               .|.|  ..|:.:|..|..:.:.||.....|:...::.:.:|:|.||.|
Zfish   391 SF---------------SASC--LTQFCILFKRTFLSIMRDSVLTHLRIMSHLGIGILIGLLYLG 438

  Fly   417 MGTSASKALFNFGFMFTIVIAYLYLPMMPVLLYFPTEINLLKREYNNQWYRLSSYYAAMVTSKLP 481
            :|..|.|.|.|.||:|..::..::..:||.:|.||.|:.:..||:.|.||.|.:||.|...:.:|
Zfish   439 IGNEAKKVLSNSGFLFFSMLFLMFAALMPTVLTFPLEMGVFLREHLNYWYSLKAYYLAKTMADVP 503

  Fly   482 SMFILAVIYLSIVYLMSSQPLEWFRFAMLFTIAFVTALTSDSFGLLI-SSRLSLVNAMFMGPVLA 545
            ...:..|.|.||||.|:|||.:..||.:...:..:|:|.:.|.|||| ::..||..|.|:|||.|
Zfish   504 FQIVFPVAYCSIVYWMTSQPSDAVRFILFLALGTLTSLVAQSLGLLIGAASTSLQVATFVGPVTA 568

  Fly   546 VPLILLSIYGIGYGGGTYISPLMRFLMHLSYLRHSMEGLVASLYDYGRADTICEDTEIFCSFKKS 610
            :|::|.|.:.:.:   ..|...::::.::||:|:..||::.|:|...|.|..|:..|. |.|:||
Zfish   569 IPVLLFSGFFVSF---DTIPKYLQWISYISYVRYGFEGVILSIYGLDREDLHCDKDET-CHFQKS 629

  Fly   611 KVLLAFLGFENMHYLWSLSCLMSFYLLFTVAAYFMIRLRL 650
            :.:|..|..|:.........|..|::...:.|||::|.::
Zfish   630 EAILKELDVEDAKLYMDFIVLGIFFISLRLIAYFVLRYKI 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_001033861.1	ABCG_EPDR	51..276	CDD:213180	121/226 (54%)
		3a01204	67..654	CDD:273361	238/603 (39%)
		ABC2_membrane	381..587	CDD:279410	70/206 (34%)
abcg1	NP_001103924.1	3a01204	67..673	CDD:273361	250/625 (40%)
		ABCG_EPDR	81..306	CDD:213180	121/226 (54%)
		ABC2_membrane	403..605	CDD:279410	70/204 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574354
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0061
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.810