DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG4822 and CG9664

DIOPT Version :9

Sequence 1:	NP_001033861.1	Gene:	CG4822 / 33170	FlyBaseID:	FBgn0031220	Length:	677	Species:	Drosophila melanogaster
Sequence 2:	NP_722889.1	Gene:	CG9664 / 33540	FlyBaseID:	FBgn0031515	Length:	609	Species:	Drosophila melanogaster

Alignment Length:	609	Identity:	201/609 - (33%)
Similarity:	324/609 - (53%)	Gaps:	44/609 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 AVNLQFSELCYVVPDQTNASKTKTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLAGFGAVCES 115
            |:.|.||::.|.:...|..|  ..|:....|:|.|..||||:|||||||:||||.||||.....:
  Fly    20 ALELHFSQVSYSLKGATKGS--TPIINEACGVFKSGRLTAILGPSGAGKSTLLNALAGFKLQGVT 82

  Fly   116 GEILVNNSPRDMRVFRKMSRYIMQTDVLDSQFTVLEMMILAANLKLGKELNLKQKLEVIDEILGM 180
            |:.|:|..|||:..|||||.||.|..|:.:..||.|.:.::.:||:......::|.::||:|:.:
  Fly    83 GQFLLNGRPRDIMSFRKMSAYIAQNFVMLNLLTVEETLRVSTDLKMPSSTAAQEKQKIIDDIIDI 147

  Fly   181 LRLKDTLNTMAQKLSGGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIALLKVLAAGGRT 245
            |:|:....|:.:.|||||.|||.|.:|||.|||::|.||||:|||.:.|.|.|..|:.||..||.
  Fly   148 LQLQSCRRTLVKNLSGGEHKRLSIGIELVTNPPIMFFDEPTSGLDCVGSYQVICHLQRLAHDGRI 212

  Fly   246 VICSIHTPSAKIFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNFGLCCPITYNPADFIIEVACLEY 310
            |:|.:|.|.:::|::.|.|.|||.|:.:|.|:...::|.....|..||..||||||.:|| |.:
  Fly   213 VVCVVHQPGSRLFQLFDDVLVLAHGEVLYAGEQREMLPTFAQSGHICPQYYNPADFALEV-CSQ- 275

  Fly   311 GGSYHEPMVEAVGNGKVARWSPPAVEGETTTTKTDTTSGASSFYERDQFDEEISPKLLEA----- 370
                                |......|:..|:.......:|...:.|.|||.:  |::.
  Fly   276 --------------------SSTTERCESLITQNKMMHSTASNVVKLQVDEETA--LIDVHKDAL 318

  Fly   371 ---------KCSWWLQYKLLLVRMLIQMWRDKSYIKLKFYMNIVLALLVGSLYFGMGTSASKALF 426
                     :..:|.|..:||.|.|..|.||...::::..|::|:|||:|.:|:.:|..|.|.:.
  Fly   319 DLSHLRGKEQVGFWTQLSVLLRRHLRSMSRDMFAVQMRLVMHVVVALLLGVVYWQIGGDAQKIVS 383

  Fly   427 NFGFMFTIVIAYLYLPMMPVLLYFPTEINLLKREYNNQWYRLSSYYAAMVTSKLPSMFILAVIYL 491
            |...:|.:::.......||.:|....:..:..|||.|.||.|.:||.:.|.:.||.......:::
  Fly   384 NVSCLFFVILFVFAGNAMPSILLCMQDSAVFIREYYNGWYSLGAYYLSKVLADLPLQLTCPTMFI 448

  Fly   492 SIVYLMSSQPLEWFRFAMLFTIAFVTALTSDSFGLLISSRLSLVNAMFMGPVLAVPLILLSIYGI 556
            ||.|.|:.||.|:.||||.:.:..:||......|::..|..::..|:|:.|...:|.:|.|.:.|
  Fly   449 SIGYFMTGQPPEFQRFAMCWALCVMTAFIGHFIGVIAGSLFTMQLAIFLVPSATIPFLLFSGFFI 513

  Fly   557 GYGGGTYISPLMRFLMHLSYLRHSMEGLVASLYDYGRADTICEDTEIFCSFKKSKVLLAFLGFEN 621
            ..   ..:|..:|.:..:|:.|:..|||:.::|.|.|.:..|..|..||.::.::..|.....|.
  Fly   514 RL---NELSWFLRPICDVSFFRYIFEGLMRAIYGYDRGELECYATSNFCYYRTAEQFLKDFQMEG 575

  Fly   622 MHYLWSLSCLMSFYLLFTVAAYFM 645
            ..:.|.:: ::..:|:..:.|:|:
  Fly   576 NEFDWDMA-VLGIFLILLLLAFFV 598

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_001033861.1	ABCG_EPDR	51..276	CDD:213180	100/224 (45%)
		3a01204	67..654	CDD:273361	196/593 (33%)
		ABC2_membrane	381..587	CDD:279410	63/205 (31%)
CG9664	NP_722889.1	ABCG_EPDR	20..243	CDD:213180	100/224 (45%)
		EcfA2	23..247	CDD:224047	100/225 (44%)
		ABC2_membrane	338..539	CDD:279410	62/203 (31%)
		YadH	<388..547	CDD:223912	47/161 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	121	1.000	Domainoid score	I1855
eggNOG	1	0.900	-	-		E2759_KOG0061
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1022017at2759
OrthoFinder	1	1.000	-	-		FOG0000053
OrthoInspector	1	1.000	-	-		mtm14984
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48041
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X52
	8	7.920