Protein Alignment CG4822 and Abcg2

DIOPT Version :10

• Sequence 1: NP_608493.2
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_852046.1
• Gene: Abcg2 / 312382
• RGDID: 631345
• Length: 657
• Species: Rattus norvegicus
• Alignment Length: 668
• Identity: 184/668 - (27%)
• Similarity: 313/668 - (46%)
• Gaps: 115/668 - (17%)

  Fly    54 LQFSELCYVVPDQTN--ASKT--KTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLA------G 108
            |.|..:.|.|..::.  ..||  |.||..:||:. ...|.||:||:|.||::||::||      |
  Rat    37 LSFHHITYRVKVKSGFLVRKTAEKEILSDINGIM-KPGLNAILGPTGGGKSSLLDVLAARKDPRG 100

  Fly   109 FGAVCESGEILVNNSPRDMRVFRKMSRYIMQTDVLDSQFTVLEMMILAANLKLGKELNLKQKLEV 173
            .     ||::|:|.:|:... |:..|.|::|.||:....||.|.:..:|.|:|.|.:...:|.|.
  Rat   101 L-----SGDVLINGAPQPAN-FKCSSGYVVQDDVVMGTLTVRENLQFSAALRLPKAMKTHEKNER 159

  Fly   174 IDEI---LGMLRLKDTL--NTMAQKLSGGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCI 233
            |:.|   ||:.::.|:.  ....:.:|||||||..|.:||:.:|.::||||||||||..:::..:
  Rat   160 INTIIKELGLDKVADSKVGTQFTRGISGGERKRTSIGMELITDPSILFLDEPTTGLDSSTANAVL 224

  Fly   234 ALLKVLAAGGRTVICSIHTPSAKIFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNFGLCCPITYNP 298
            .|||.::..|||:|.|||.|...||::.|::.:||.|:.::.|.....:.:..:.|..|....||
  Rat   225 LLLKRMSKQGRTIIFSIHQPRYSIFKLFDSLTLLASGKLMFHGPAQKALEYFASAGYHCEPYNNP 289

  Fly   299 ADFIIEV-------ACLEYGGSYHE------------PMVEAVGNGKVARWSPPAVEGETTT--- 341
            |||.::|       ..|..|...||            |::|.:....:    ...:.|||..
  Rat   290 ADFFLDVINGDSSAVMLNRGEQDHEANKTEEPSKREKPIIENLAEFYI----NSTIYGETKAELD 350

  Fly   342 --TKTDTTSGASSFYERDQFDEEISPKLLEAKCSW--WL---QYKLLL------VRMLIQMWRDK 393
              .......|:|:|.|         |..:.:.|..  |:   .:|.||      |..||
  Rat   351 QLPVAQKKKGSSAFRE---------PVYVTSFCHQLRWIARRSFKNLLGNPQASVAQLI------ 400

  Fly   394 SYIKLKFYMNIVLALLVGSLYFGMGTSASKALFNFGFMFTIVIAYLYLPMMPVLLYFPTEINLLK 458
                    :.::|.|::|:||||:....:......|..|.:.....:..:..|.| |..|..|..
  Rat   401 --------VTVILGLIIGALYFGLKNDPTGMQNRAGVFFFLTTNQCFTSVSAVEL-FVVEKKLFI 456

  Fly   459 REYNNQWYRLSSY-YAAMVTSKLPSMFILAVIYLSIVYLM--SSQPLEWFRFAMLFTIAFVTALT 520
            .||.:.:||:||| :..:|:..||..|:.:|||..::|.|  ..:.:|.| |.|:||:..| |.|
  Rat   457 HEYISGYYRVSSYFFGKLVSDLLPMRFLPSVIYTCLLYFMLGLKRTVEAF-FIMMFTLIMV-AYT 519

  Fly   521 SDSFGLLISSRLSLVNAMFMGPVLAVPLILLSIY-GIGYGGGTYISPLMRFLMHLSYLRHSMEGL 584
            :.|..|.|::..|:|:...:  ::.:..:.:.:: |:.....| |.|.:.:|.:.|..|:....|
  Rat   520 ASSMALAIAAGQSVVSVATL--LMTISFVFMMLFSGLLVNLRT-IGPWLSWLQYFSIPRYGFTAL 581

  Fly   585 VASLYDYGR---------ADTICEDTEIFCSFKKSKVLLAFLGFENMHY-LW----SLSCLMSFY 635
            ..:.: .|:         .::.|.::...|:   ....|...|.:...: ||    :|:|::
  Rat   582 QHNEF-LGQEFCPGLNVTMNSTCVNSYTICT---GNDYLINQGIDLSPWGLWRNHVALACMI--- 639

  Fly   636 LLFTVAAYFMIRLRLKHS 653
            ::|...||..:....|:|
  Rat   640 IIFLTIAYLKLLFLKKYS 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_608493.2	3a01204	67..654	CDD:273361	180/655 (27%)
Abcg2	NP_852046.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		3a01204	46..651	CDD:273361	179/651 (27%)