Protein Alignment CG4822 and Abcg5

DIOPT Version :10

• Sequence 1: NP_608493.2
• Gene: CG4822 / 33170
• FlyBaseID: FBgn0031220
• Length: 677
• Species: Drosophila melanogaster
• Sequence 2: NP_114090.1
• Gene: Abcg5 / 27409
• MGIID: 1351659
• Length: 652
• Species: Mus musculus
• Alignment Length: 580
• Identity: 149/580 - (25%)
• Similarity: 243/580 - (41%)
• Gaps: 123/580 - (21%)

  Fly    73 KTILRRVNGMFHSHELTAIIGPSGAGKTTLLNLLAG----FGAVCESGEILVNNSPRDMRVFRKM 133
            :.||:.|:....|.::..|:|.||:||||||:.::|    .|.:  .||:.||........|:..
Mouse    67 RQILKDVSLYIESGQIMCILGSSGSGKTTLLDAISGRLRRTGTL--EGEVFVNGCELRRDQFQDC 129

  Fly   134 SRYIMQTDVLDSQFTVLEMMILAANLKLGK---------------ELNLKQKLEVIDEILGMLRL 183
            ..|::|:||..|..||.|.:...|.|.|.:               ||:|.   .|.|:::|....
Mouse   130 FSYVLQSDVFLSSLTVRETLRYTAMLALCRSSADFYNKKVEAVMTELSLS---HVADQMIGSYNF 191

  Fly   184 KDTLNTMAQKLSGGERKRLCIALELVNNPPVIFLDEPTTGLDDLSSSQCIALLKVLAAGGRTVIC 248
            ..        :|.|||:|:.||.:|:.:|.|:.|||||||||.::::|.:.||..||...|.||.
Mouse   192 GG--------ISSGERRRVSIAAQLLQDPKVMMLDEPTTGLDCMTANQIVLLLAELARRDRIVIV 248

  Fly   249 SIHTPSAKIFEMLDAVYVLAEGQCVYQGKGSNIVPFLKNFGLCCPITYNPADFIIEVACLEYGGS 313
            :||.|.:::|:..|.:.:|..|:.|:.|....::.|..|.|..||...||.||.:::
Mouse   249 TIHQPRSELFQHFDKIAILTYGELVFCGTPEEMLGFFNNCGYPCPEHSNPFDFYMDL-------- 305

  Fly   314 YHEPMVEAVGNGKVARWSPPAVEGETTTTKTDTTSGASSF--YERDQF------DEEISPKLLE- 369
                                        |..||.|.....  |:|.|.      :.:|..|:||
Mouse   306 ----------------------------TSVDTQSREREIETYKRVQMLECAFKESDIYHKILEN 342

  Fly   370 ------AKCSWWLQYK------------LLLVRMLIQMWRDKSYIKLKFYMNIVLALLVGSLYFG 416
                  .|....:.:|            :||.|:...:.|:|..:.::...|:::.|.:......
Mouse   343 IERARYLKTLPTVPFKTKDPPGMFGKLGVLLRRVTRNLMRNKQAVIMRLVQNLIMGLFLIFYLLR 407

  Fly   417 MGTSASKALF--NFGFMFTIVIAYLYLPMMPVLLYFPTEINLLKREYNNQWYRLSSYYAAMVTSK 479
            :..:..|...  ..|.::.:|.|..|..|:..:..||....:..:|..:..|.......|.|...
Mouse   408 VQNNTLKGAVQDRVGLLYQLVGATPYTGMLNAVNLFPMLRAVSDQESQDGLYHKWQMLLAYVLHV 472

  Fly   480 LPSMFILAVIYLSIVYLMSSQPLEWFRFAMLFTIAFVTALTSDSFGLLISSRLSLV------NAM 538
            ||...|..||:.|:.|.......|..||..     |..||.:..   ||...|:||      |..
Mouse   473 LPFSVIATVIFSSVCYWTLGLYPEVARFGY-----FSAALLAPH---LIGEFLTLVLLGIVQNPN 529

  Fly   539 FMGPVLAVPLILLSIYGIGYGGGTYISPL------MRFLMHLSYLRHSMEGLVASLYDYG 592
            .:..::|    ||||.|:..|.| :|..:      ::.|.:.::.::..|.||.:.: ||
Mouse   530 IVNSIVA----LLSISGLLIGSG-FIRNIQEMPIPLKILGYFTFQKYCCEILVVNEF-YG 583

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4822	NP_608493.2	3a01204	67..654	CDD:273361	149/580 (26%)
Abcg5	NP_114090.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..25
		ABCG_White	50..276	CDD:213201	73/221 (33%)
		3a01204	61..646	CDD:273361	149/580 (26%)